Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Maria Pujantell"'
Autor:
Maria Pujantell, Nikolaos-Taxiarchis Skenteris, Janna Marieke Claussen, Benjamin Grünhagel, Rebecca-Jo Thiele, Marcus Altfeld
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells are important antiviral effector cells and also involved in tumor clearance. NK cells express IFNAR, rendering them responsive to Type I IFNs. To evaluate Type I IFN-mediated modulation of NK cell functions, individual Type
Externí odkaz:
https://doaj.org/article/9fb70753e1bd49c698bbfbb5552c40fc
Autor:
Benjamin Grünhagel, Malte Borggrewe, Sven Hendrik Hagen, Susanne M. Ziegler, Florian Henseling, Laura Glau, Rebecca-Jo Thiele, Maria Pujantell, Varshi Sivayoganathan, Benedetta Padoan, Janna M. Claussen, Arne Düsedau, Jana Hennesen, Madeleine J. Bunders, Stefan Bonn, Eva Tolosa, Christian F. Krebs, Christoph Dorn, Marcus Altfeld
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108209- (2023)
Summary: Type I interferons (IFN-I) are important mediators of antiviral immunity and autoimmune diseases. Female plasmacytoid dendritic cells (pDCs) exert an elevated capacity to produce IFN-I upon toll-like receptor 7 (TLR7) activation compared to
Externí odkaz:
https://doaj.org/article/3e9659bff4ad40d09be5365c3478f73a
Autor:
Chloé Pasin, Camila R. Consiglio, Jana S. Huisman, Ann-Marie G. de Lange, Hannah Peckham, Enriqueta Vallejo-Yagüe, Irene A. Abela, Ulrika Islander, Nadia Neuner-Jehle, Maria Pujantell, Olivia Roth, Melanie Schirmer, Burcu Tepekule, Marius Zeeb, Anna Hachfeld, Karoline Aebi-Popp, Roger D. Kouyos, Sebastian Bonhoeffer
Publikováno v:
Royal Society Open Science, Vol 10, Iss 7 (2023)
Although sex and gender are recognized as major determinants of health and immunity, their role is rarely considered in clinical practice and public health. We identified six bottlenecks preventing the inclusion of sex and gender considerations from
Externí odkaz:
https://doaj.org/article/5fc47d8be8ec4bdd9319e0dcba11b120
Autor:
Maria Pujantell, Marcus Altfeld
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The immune system protects us from pathogens, such as viruses. Antiviral immune mechanisms aim to limit viral replication, and must maintain immunological homeostasis to avoid excessive inflammation and damage to the host. Sex differences in the mani
Externí odkaz:
https://doaj.org/article/91e8d955d28b47579e79ce29550dcdb1
Autor:
Roger Badia, Ester Ballana, Marc Castellví, Edurne García-Vidal, Maria Pujantell, Bonaventura Clotet, Julia G. Prado, Jordi Puig, Miguel A. Martínez, Eva Riveira-Muñoz, José A. Esté
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
CD32 has been previously shown to be expressed preferentially by CD4 T cells latently harbouring HIV-1. Here the authors show that CD32 expression in CD4 T cells is associated with T cell activation, is up-regulated by HIV-1 infection and importantly
Externí odkaz:
https://doaj.org/article/7e50053306594d9bbbe279cb0c8a7902
Autor:
Maria Pujantell, Eva Riveira-Muñoz, Roger Badia, Marc Castellví, Edurne Garcia-Vidal, Guillem Sirera, Teresa Puig, Cristina Ramirez, Bonaventura Clotet, José A. Esté, Ester Ballana
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. H
Externí odkaz:
https://doaj.org/article/b5349f651b58471ab2d3235a717d05d0
Autor:
Maria Pujantell, Eva Riveira-Muñoz, Edurne García-Vidal, Lucía Gutiérrez-Chamorro, Roger Badia, Bonaventura Clotet, Ester Ballana
Publikováno v:
Proceedings, Vol 50, Iss 1, p 34 (2020)
Viral infection induces innate intracellular antiviral defenses, aimed at restricting virus replication and spread. Therefore, understanding the role and function of innate immune modulators can help to establish novel strategies for viral control. H
Externí odkaz:
https://doaj.org/article/78a4df2d543245b78c3e3a4f3ba84030
Autor:
Ifeanyi Ezeonwumelu, Marc Castellví, Eudald Felip, Maria Pujantell, Edurne Garcia-Vidal, Eva Riveira-Muñoz, Roger Badia, Bonaventura Clotet, Mireia Margelí, Ester Ballana
Publikováno v:
Proceedings, Vol 50, Iss 1, p 58 (2020)
Nucleos(t)ide analogues are commonly used in the treatment of infectious disease and cancer. SAMHD1 is a deoxyribonucleotide (dNTP) triphosphohydrolase which is involved in the regulation of the intracellular dNTP pool, whose function has been linked
Externí odkaz:
https://doaj.org/article/650677a9fc06475694185e6f4c7dc69b
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186277 (2017)
The enzyme tRNase Z, a member of the metallo-β-lactamase family, endonucleolytically removes 3' trailers from precursor tRNAs, preparing them for CCA addition and aminoacylation. The short form of tRNase Z, tRNase ZS, functions as a homodimer and is
Externí odkaz:
https://doaj.org/article/1bea47bb74834e998137b49b6f1762c9
Autor:
Roger Badia, Maria Pujantell, Eva Riveira-Muñoz, Teresa Puig, Javier Torres-Torronteras, Ramón Martí, Bonaventura Clotet, Rosa M Ampudia, Marta Vives-Pi, José A Esté, Ester Ballana
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005829 (2016)
Macrophages are a heterogeneous cell population strongly influenced by differentiation stimuli that become susceptible to HIV-1 infection after inactivation of the restriction factor SAMHD1 by cyclin-dependent kinases (CDK). Here, we have used primar
Externí odkaz:
https://doaj.org/article/8d8f703dd2734ebc939401a5815668b2