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Autor:
Marja Jäättelä, David A. Egan, Christoffel Dinant, Tiina Naumanen Dietrich, Inger Ødum Nielsen, Maria Postol, Kenji Maeda, Siri Amanda Tvingsholm, Tuula Kallunki, Malene Hansen, Pietri Puustinen, Robert Strauss
Publikováno v:
Hansen, M B, Postol, M, Tvingsholm, S, Nielsen, I Ø, Dietrich, T N, Puustinen, P, Maeda, K, Dinant, C, Strauss, R, Egan, D, Jäättelä, M & Kallunki, T 2021, ' Identification of lysosome-targeting drugs with anti-inflammatory activity as potential invasion inhibitors of treatment resistant HER2 positive cancers ', Cellular Oncology, vol. 44, pp. 805–820 . https://doi.org/10.1007/s13402-021-00603-2
Cellular Oncology (Dordrecht)
Cellular Oncology (Dordrecht)
Purpose Most HER2 positive invasive cancers are either intrinsic non-responsive or develop resistance when treated with 1st line HER2 targeting drugs. Both 1st and 2nd line treatments of HER2 positive cancers are aimed at targeting the HER2 receptor