Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Maria Plana"'
Autor:
Sandra Llop, Maria Plana, Sara Tous, Angelica Ferrando-Díez, Jesús Brenes, Marc Juarez, Zara Vidales, Esther Vilajosana, Isabel Linares, Lorena Arribas, Maria Duch, Marta Fulla, Aina Brunet, Alicia Lozano, Beatriz Cirauqui, Ricard Mesía, Marc Oliva
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectivesAnti-PD-(L)1 agents changed the landscape of recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) treatment. Previous studies showed improved response rates to salvage chemotherapy (SCT) after progression to anti-PD-(L)
Externí odkaz:
https://doaj.org/article/d28979b34c654b3691bc6bfc78e1d85b
Autor:
Ana Varges Gomes, Gilberto Castro, Thiago Bueno de Oliveira, Ana Medina Colmenero, Leonor Ribeiro, Amanda Psyrri, Nicolas Magné, Maria Plana Serrahima, Joana Marinho, Raul Giglio, Leticia Iglesias Rey, Martín Angel, Ana M. Macedo
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionSquamous cell carcinoma of the head and neck (SCCHN) is a multifactorial disease involving genetic and environmental factors representing one of the most frequent cancer-related deaths worldwide. Tobacco and alcohol use account for most S
Externí odkaz:
https://doaj.org/article/50416f7b34e94d5d9d3fe2911ba07be2
Autor:
Jordi Rubió-Casadevall, Beatriz Cirauqui Cirauqui, Javier Martinez Trufero, Maria Plana Serrahima, Almudena García Castaño, Alberto Carral Maseda, Lara Iglesias Docampo, Pedro Pérez Segura, Isaac Ceballos Lenza, Vanesa Gutiérrez Calderón, José Fuster Salvà, Carolina Pena Álvarez, Irene Hernandez, Edel del Barco Morillo, Manuel Chaves Conde, Joaquina Martínez Galán, Marisa Durán Sánchez, Vanesa Quiroga, Eugenia Ortega, Ricard Mesia
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectivesThe aim of this study was to confirm the efficacy of the ERBITAX scheme (paclitaxel 80 mg/m2 weekly and cetuximab 400 mg/m2 loading dose, and then 250 mg/m2 weekly) as first-line treatment for patients with recurrent/metastatic squamous cel
Externí odkaz:
https://doaj.org/article/2c2ce3b877f44930902325a31aadefe0
Autor:
Juan A. Marín-Jiménez, Marc Oliva, Paloma Peinado Martín, Santiago Cabezas-Camarero, Maria Plana Serrahima, Gonzalo Vázquez Masedo, Alicia Lozano Borbalas, María N. Cabrera Martín, Anna Esteve, María C. Iglesias Moreno, Esther Vilajosana Altamis, Lorena Arribas Hortigüela, Miren Taberna Sanz, Pedro Pérez-Segura, Ricard Mesía
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesInduction chemotherapy (ICT) followed by definitive treatment is an accepted non-surgical approach for locoregionally advanced head and neck squamous cell carcinoma (LA-HNSCC). However, ICT remains a challenge for cisplatin-unfit patients.
Externí odkaz:
https://doaj.org/article/9d6af13842bf47e6b926fa2e5a09c1cc
Autor:
Lorena Arribas, Maria Plana, Miren Taberna, Maria Sospedra, Noelia Vilariño, Marc Oliva, Natalia Pallarés, Ana Regina González Tampán, Luis Miguel Del Rio, Ricard Mesia, Vickie Baracos
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundReduced muscle mass has been associated with increased treatment complications in several tumor types. We evaluated the impact of skeletal muscle index (SMI) on prognosis and immune-related adverse events (IrAEs) in a cohort of recurrent/me
Externí odkaz:
https://doaj.org/article/4461a9fc8b9f49d893d56b35fd55aad4
Autor:
Estefania Alcaraz, Jordi Vilardell, Christian Borgo, Eduard Sarró, Maria Plana, Oriano Marin, Lorenzo A Pinna, José R Bayascas, Anna Meseguer, Mauro Salvi, Emilio Itarte, Maria Ruzzene
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227340 (2020)
The PI3K/Akt pathway is interconnected to protein kinase CK2, which directly phosphorylates Akt1 at S129. We have previously found that, in HK-2 renal cells, downregulation of the CK2 regulatory subunit β (shCK2β cells) reduces S129 Akt phosphoryla
Externí odkaz:
https://doaj.org/article/69543d1d78a64740811782633ddbd0bf
Autor:
Laura Ferrer-Font, Lucia Villamañan, Nuria Arias-Ramos, Jordi Vilardell, Maria Plana, Maria Ruzzene, Lorenzo A. Pinna, Emilio Itarte, Carles Arús, Ana Paula Candiota
Publikováno v:
Pharmaceuticals, Vol 10, Iss 1, p 24 (2017)
Glioblastoma (GBM) causes poor survival in patients even with aggressive treatment. Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment but resistance always ensues. Protein kinase CK2 (CK2) contributes to tumour development
Externí odkaz:
https://doaj.org/article/e670bbaecb9a42958d9d85d51579d85e
Autor:
Olga Tornavaca, Eduard Sarró, Gloria Pascual, Beatriz Bardaji, M Angeles Montero, M Teresa Salcedo, Maria Plana, Joan López-Hellin, Emilio Itarte, Anna Meseguer
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25746 (2011)
The use of cyclosporine A (CsA) is limited by its severe nephrotoxicity that includes reversible vasoconstrictor effects and proximal tubule cell injury, the latter associated whith chronic kidney disease progression. The mechanisms of CsA-induced tu
Externí odkaz:
https://doaj.org/article/ba9429455e464ae4a4261e9e29aa6d92
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