Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria Pia, Polito"'
Autor:
Maria Pia Polito, Alessio Romaldini, Lorenzo Tagliazucchi, Grazia Marini, Federica Radice, Gaia Andrea Gozza, Giulia Bergamini, Maria Paola Costi, Elena Enzo
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract The complex network governing self-renewal in epidermal stem cells (EPSCs) is only partially defined. FOXM1 is one of the main players in this network, but the upstream signals regulating its activity remain to be elucidated. In this study,
Externí odkaz:
https://doaj.org/article/665845e23c074f57b29992a9da55e292
Coordinating energy metabolism and signaling pathways in epithelial self-renewal and differentiation
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Epidermal stem cells (EPSCs) are essential for maintaining skin homeostasis and ensuring a proper wound healing. During in vitro cultivations, EPSCs give rise to transient amplifying progenitors and differentiated cells, finally forming a st
Externí odkaz:
https://doaj.org/article/7be09cfcace941baa12b3bf3a0216e02
Autor:
Maria Pia Polito, Grazia Marini, Alessandra Fabrizi, Laura Sercia, Elena Enzo, Michele De Luca
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-10 (2024)
Abstract Epidermal stem cells orchestrate epidermal renewal and timely wound repair through a tight regulation of self-renewal, proliferation, and differentiation. In culture, human epidermal stem cells generate a clonal type referred to as holoclone
Externí odkaz:
https://doaj.org/article/c421b30b8308404a98973d249cce780e
Autor:
Elena Enzo, Alessia Secone Seconetti, Mattia Forcato, Elena Tenedini, Maria Pia Polito, Irene Sala, Sonia Carulli, Roberta Contin, Clelia Peano, Enrico Tagliafico, Silvio Bicciato, Sergio Bondanza, Michele De Luca
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Epidermal cultures can treat skin diseases, such as Junctional Epidermolysis Bullosa, but the signature of stem cells is unclear. By single cell RNAseq analyses on human keratinocytes, the authors identify the molecular profile of holoclones and the
Externí odkaz:
https://doaj.org/article/24ade267e8ad41b39a4b9790df32c377
Publikováno v:
International Journal of Molecular Sciences. 24:8544
The epidermis is one of the largest tissues in the human body, serving as a protective barrier. The basal layer of the epidermis, which consists of epithelial stem cells and transient amplifying progenitors, represents its proliferative compartment.
Autor:
Elena, Enzo, Camilla, Cattaneo, Federica, Consiglio, Maria Pia, Polito, Sergio, Bondanza, Michele, De Luca
Regenerative medicine has its roots in harnessing stem cells for permanent restoration of damaged or diseased tissues. The first procedure for the transplantation of epidermal cultures in massive full-thickness burns was established in the 1980s. Sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::96af619608cdc90bdb4af62809fac8a6
https://hdl.handle.net/11380/1279605
https://hdl.handle.net/11380/1279605