Výsledky vyhledávání - "Maria Pelliccia"

Akademický článek

The different ways to chitosan/hyaluronic acid nanoparticles: templated vs direct complexation. Influence of particle preparation on morphology, cell uptake and silencing efficiency

Autor: Arianna Gennari, Julio M. Rios de la Rosa, Erwin Hohn, Maria Pelliccia, Enrique Lallana, Roberto Donno, Annalisa Tirella, Nicola Tirelli

Publikováno v: Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2594-2608 (2019)

This study is about linking preparative processes of nanoparticles with the morphology of the nanoparticles and with their efficiency in delivering payloads intracellularly. The nanoparticles are composed of hyaluronic acid (HA) and chitosan; the for

Externí odkaz: https://doaj.org/article/6c810137231e4d0e90644af28977b353

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Akademický článek

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

Autor: Maria Pelliccia, Patrizia Andreozzi, Jayson Paulose, Marco D’Alicarnasso, Valeria Cagno, Manuela Donalisio, Andrea Civra, Rebecca M. Broeckel, Nicole Haese, Paulo Jacob Silva, Randy P. Carney, Varpu Marjomäki, Daniel N. Streblow, David Lembo, Francesco Stellacci, Vincenzo Vitelli, Silke Krol

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)

Keeping viral vaccines cold from the manufacturers to patients is problematic and costly. Here, Krol and others show additives that can significantly improve at very low concentrations the storage of adenovirus type 5 at ambient and elevated temperat

Externí odkaz: https://doaj.org/article/6897222ac66a4957bef12c2b0a62fd79

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The different ways to chitosan/hyaluronic acid nanoparticles: templated vs direct complexation. Influence of particle preparation on morphology, cell uptake and silencing efficiency

Autor: Roberto Donno, Erwin Hohn, Maria Pelliccia, Nicola Tirelli, Arianna Gennari, Julio M. Rios de la Rosa, Annalisa Tirella, Enrique Lallana

Publikováno v: Gennari, A, Rios de la Rosa, J M, Hohn, E, Pelliccia, M, Lallana, E, Donno, R, Tirella, A & Tirelli, N 2019, ' The different ways to chitosan/hyaluronic acid nanoparticles: templated vs. direct complexation. Influence of particle preparative processes on morphology, cell uptake and silencing efficiency ', Beilstein Journal of Nanotechnology, vol. 2019, no. 10, pp. 2594–2608 . https://doi.org/10.3762/bjnano.10.250
Beilstein Journal of Nanotechnology
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2594-2608 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47242911cb7a0e165d188efb24257c24
https://doi.org/10.3762/bjnano.10.250

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Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

Autor: Maria Pelliccia, Brenton A. G. Hammer, Tanja Weil, Patrizia Andreozzi, Weina Liu, Johanna Simon, Sabyasachi Chakrabortty, Klaus Müllen, Seah Ling Kuan, Jessica Wagner, Francesco Stellacci, Silke Krol, Katharina Landfester, Yuzhou Wu, Florian Kreppel, Marco D'Alicarnasso, Longjie Li, Larissa Frank

Publikováno v: ACS Nano

The surface of proteins is heterogeneous with sophisticated but precise hydrophobic and hydrophilic patches, which is essential for their diverse biological functions. To emulate such distinct surface patterns on macromolecules, we used rigid spheric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa20e93c6cf2b5bc8a6100c684e1c17
http://europepmc.org/articles/PMC6716120

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Tyrosinase-Mediated Bioconjugation. A Versatile Approach to Chimeric Macromolecules

Autor: Elita Montanari, Maria Pelliccia, Neil J. Oldham, Andrew S. MacDonald, Roberto Donno, Arianna Gennari, Nicola Tirelli, Lucio Manzi

Publikováno v: Bioconjugate Chemistry. 29:2550-2560

We present a method for tyrosine-selective and reversible bioconjugation; tyrosines are enzymatically converted into catechols and in situ "clicked" onto boronic acids. Importantly, our process selectively produces catechols and avoids quinones, ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cc91c4fea393b229c7fd59e6d60266
https://doi.org/10.1021/acs.bioconjchem.8b00227

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Self-replicating RNA vaccine functionality modulated by fine-tuning of polyplex delivery vehicle structure

Autor: Kenneth C. McCullough, Nicolas Ruggli, Thomas Ebensen, Carlos Guzmán, Maria Pelliccia, Pavlos C. Englezou, Kai Schulze, Thomas Démoulins

Publikováno v: Journal of Controlled Release. 266:256-271

The major limitations with large and complex self-amplifying RNA vaccines (RepRNA) are RNase-sensitivity and inefficient translation in dendritic cells (DCs). Condensing RepRNA with polyethylenimine (PEI) gave positive in vitro readouts, but was larg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b6f58ef30851001f0e1a773e635ea7
https://doi.org/10.1016/j.jconrel.2017.09.018

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Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation

Autor: Maria Pelliccia, Sarah J. Butcher, Visa Ruokolainen, Aušra Domanska, Varpu Marjomäki, Mira Laajala

There is limited information about the molecular triggers leading to the uncoating of enteroviruses under physiological conditions. Using real-time spectroscopy and sucrose gradients with radioactively labeled virus, we show at 37°C, the formation o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b705fccaa7d5a78419d45bf5c7b1f6b
https://europepmc.org/articles/PMC6694817/

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Correction to Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

Autor: Francesco Stellacci, Katharina Landfester, Sabyasachi Chakrabortty, Yuzhou Wu, Johanna Simon, Longjie Li, Maria Pelliccia, Florian Kreppel, Patrizia Andreozzi, Jessica Wagner, Weina Liu, Tanja Weil, Silke Krol, Larissa Frank, Brenton A. G. Hammer, Seah Ling Kuan, Marco D'Alicarnasso, Klaus Müllen

Publikováno v: ACS Nano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bbd0a1cfdb1a74a59b9b91b790f11f
https://doi.org/10.1021/acsnano.0c10327

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Enteral Nutrition Support Reduces the Necessity of Total Parenteral Nutrition to Reach Patient-Specific Caloric Goals Postpancreaticoduodenectomy

Autor: Maria Pelliccia, Natalie G. Coburn, Myles Smith, Paul J. Karanicolas, Katherine Vandenbussche, Mario H Mueller, Sherif S. Hanna, Calvin Law

Publikováno v: Southern Medical Journal. 108:748-753

Objectives Pancreaticoduodenectomy (PD) is associated with significant rates of postoperative complications. Although there is evidence that enteral nutrition support (ENS) may reduce postoperative sepsis, the true value of ENS in the abrogation of s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73464a40e4b90ac2a01011d66c0d8093
https://doi.org/10.14423/smj.0000000000000385

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Chitosan/Hyaluronic Acid Nanoparticles: Rational Design Revisited for RNA Delivery

Autor: Sanyogitta Puri, Maria Pelliccia, Arianna Gennari, Marianne Ashford, Julio M. Rios de la Rosa, Annalisa Tirella, Ian J. Stratford, Nicola Tirelli, Enrique Lallana

Publikováno v: Molecular pharmaceutics. 14(7)

Chitosan/hyaluronic acid (HA) nanoparticles can be used to deliver an RNA/DNA cargo to cells overexpressing HA receptors such as CD44. For these systems, unequivocal links have not been established yet between chitosan macromolecular (molecular weigh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a097045c3fb522e916598240f0a5bc03
https://pubmed.ncbi.nlm.nih.gov/28597662

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