Výsledky vyhledávání - "Maria Pazos-Gil"

Akademický článek

Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response

Autor: Arabela Sanz-Alcázar, Marta Portillo-Carrasquer, Fabien Delaspre, Maria Pazos-Gil, Jordi Tamarit, Joaquim Ros, Elisa Cabiscol

Publikováno v: Redox Biology, Vol 76, Iss , Pp 103339- (2024)

Friedreich ataxia (FA) is a rare neurodegenerative disease caused by decreased levels of the mitochondrial protein frataxin. Frataxin has been related in iron homeostasis, energy metabolism, and oxidative stress. Ferroptosis has recently been shown t

Externí odkaz: https://doaj.org/article/9b59a3a421f5404c971987defaf49e32

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Deficient mitochondrial respiration impairs sirtuin activity in dorsal root ganglia in Friedreich Ataxia mouse and cell models

Autor: Arabela Sanz-Alcázar, Elena Britti, Fabien Delaspre, Marta Medina-Carbonero, Maria Pazos-Gil, Jordi Tamarit, Joaquim Ros, Elisa Cabiscol

Friedreich ataxia (FA) is a rare, recessive neuro-cardiodegenerative disease caused by deficiency of the mitochondrial protein frataxin. Mitochondrial dysfunction, a reduction in the activity of iron-sulfur enzymes, iron accumulation, and increased o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11690086071ba22b0e8bd95fbb1cadd7
https://doi.org/10.1101/2023.02.01.526688

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Evolution of an Iron-Detoxifying Protein: Eukaryotic and

Autor: Rui, Alves, Maria, Pazos-Gil, Marta, Medina-Carbonero, Arabela, Sanz-Alcázar, Fabien, Delaspre, Jordi, Tamarit

Publikováno v: International journal of molecular sciences. 23(21)

Friedreich's ataxia is a neurodegenerative disease caused by mutations in the frataxin gene. Frataxin homologues, including bacterial CyaY proteins, can be found in most species and play a fundamental role in mitochondrial iron homeostasis, either pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3212a204785e098a7028b8841018bfb8
https://pubmed.ncbi.nlm.nih.gov/36361939

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Evolution of an Iron-Detoxifying Protein: Eukaryotic and Rickettsia Frataxins Contain a Conserved Site Which Is Not Present in Their Bacterial Homologues

Autor: Rui Alves, Maria Pazos-Gil, Marta Medina-Carbonero, Arabela Sanz-Alcázar, Fabien Delaspre, Jordi Tamarit

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13151

Friedreich’s ataxia is a neurodegenerative disease caused by mutations in the frataxin gene. Frataxin homologues, including bacterial CyaY proteins, can be found in most species and play a fundamental role in mitochondrial iron homeostasis, either

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed72e0e7262c5aa3697d7d69aeea2c0f
https://hdl.handle.net/10459.1/84485

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