Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maria Pagratis"'
Autor:
Dylan J. Taatjes, Zachary C. Poss, Helen Simpson, Maria Pagratis, William M. Old, Steven E. Guard, Christopher C. Ebmeier
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
The chromosome 21 encoded protein kinase DYRK1A is essential for normal human development. Mutations in DYRK1A underlie a spectrum of human developmental disorders, and increased dosage in trisomy 21 is implicated in Down syndrome related pathologies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488515d4ece93d83a3b7808638d72218
https://doi.org/10.1038/s41598-019-42990-5
https://doi.org/10.1038/s41598-019-42990-5
Autor:
Maria Pagratis, Dylan J. Taatjes, Zachary C. Poss, Christopher C. Ebmeier, William M. Old, Steven E. Guard
Loss of function mutations in the protein kinase DYRK1A lead to a syndromic form of autism spectrum disorder and intellectual disability. Conversely, increased DYRK1A dosage is implicated in atypical brain development and neurocognitive deficits in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0a72a7e67f2b92f5f1617994f511e6
Autor:
Zachary C. Poss, Maria Pagratis, Helen Simpson, Tristan D. McClure-Begley, Christopher C. Ebmeier, William M. Old
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c182a4ac110d3eebb9a3ee749f29b3d
https://doi.org/10.1096/fasebj.2018.32.1_supplement.662.22
https://doi.org/10.1096/fasebj.2018.32.1_supplement.662.22
Autor:
Jennifer M. Gardner, Andreas Hoenger, Christopher J. Ackerson, Mark Winey, Eileen T. O'Toole, Sue L. Jaspersen, Janet B. Meehl, J R McIntosh, Cynthia Page, Mary K. Morphew, Maria Pagratis, Thomas H. Giddings
Publikováno v:
Journal of Microscopy. 260:20-29
A benign, clonable tag for the localization of proteins by electron microscopy of cells would be valuable, especially if it provided labelling with high signal-to-noise ratio and good spatial resolution. Here we explore the use of metallothionein as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c0434bace4cc1344c470b6cba98bf9f
https://doi.org/10.1111/jmi.12262
https://doi.org/10.1111/jmi.12262
Autor:
Maria Pagratis, Chad G. Pearson, Eric J. Verbeke, Loren E. Hough, Geoffrey S. Armstrong, Jeremy L. Balsbaugh, Kathryn P. Wall
Publikováno v:
ACS chemical biology. 11(11)
Tubulin is important for a wide variety of cellular processes including cell division, ciliogenesis, and intracellular trafficking. To perform these diverse functions, tubulin is regulated by post-translational modifications (PTM), primarily at the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653972dc4616e11bc6490ca85bc0bdcb
https://pubmed.ncbi.nlm.nih.gov/27541566
https://pubmed.ncbi.nlm.nih.gov/27541566
Publikováno v:
Biophysical Journal. 110(3)
Microtubules made from α-β tubulin heterodimers are important for cell migration, long range transport in cells, and cell division. The disordered C-terminal tails (CTT) are a primary site of tubulin regulation. Tubulin CTT affect microtubule (MT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a19fba1d63d9f9570f93c6eaba044c
Publikováno v:
Neuroscience. 167:135-142
Fusion of synaptic vesicles with the plasma membrane is mediated by the SNARE (soluble NSF attachment receptor) proteins and is regulated by synaptotagmin (syt). There are at least 17 syt isoforms that have the potential to act as modulators of membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f78f9fc57c4f7d86070c608f7f632f
https://doi.org/10.1016/j.neuroscience.2010.01.056
https://doi.org/10.1016/j.neuroscience.2010.01.056
Autor:
Kathryn P. Wall, Maria Pagratis, Jeremy L. Balsbaugh, Chad G. Pearson, Loren E. Hough, Geoffrey S. Armstrong
Publikováno v:
Biophysical Journal. 112:563a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1247d0c43a6d33c9c30b33a845ddf03b
https://doi.org/10.1016/j.bpj.2016.11.3033
https://doi.org/10.1016/j.bpj.2016.11.3033
Publikováno v:
Applied and Environmental Microbiology. 65:640-647
High-level expression of soluble recombinant human hemoglobin (rHb) in Escherichia coli was obtained with several hemoglobin variants. Under identical conditions, two rHbs containing the Presbyterian mutation (Asn-108→Lys) in β-globin accumulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7229b36e96966631c594a3e8fdb497e
https://doi.org/10.1128/aem.65.2.640-647.1999
https://doi.org/10.1128/aem.65.2.640-647.1999
Publikováno v:
Applied and Environmental Microbiology. 63:4313-4320
Accumulation of soluble recombinant hemoglobin (rHb1.1) in Escherichia coli requires proper protein folding, prosthetic group (heme) addition, and subunit assembly. This served as a new model system for the study of the effects of temperature, protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f616f46a0d435e529cf462a013963b16
https://doi.org/10.1128/aem.63.11.4313-4320.1997
https://doi.org/10.1128/aem.63.11.4313-4320.1997