Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Maria P. Varela"'
Autor:
Syed M. Faisal, Jarred E. Clewner, Brooklyn Stack, Maria L. Varela, Andrea Comba, Grace Abbud, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) remains a challenge in Neuro‐oncology, with a poor prognosis showing only a 5% survival rate beyond two years. This is primarily due to its aggressiveness and intra‐tumoral heterogeneity, which limits complete surgical
Externí odkaz:
https://doaj.org/article/1538c238cfc34c618bb0253cf99982f3
Publikováno v:
SLAS Discovery, Vol 29, Iss 3, Pp 100149- (2024)
The purpose of the protocol reported in this work is the solubility profiling of large chemical libraries using nephelometry. This technique allows the qualitative classification of compounds as highly, moderately, or poorly water-soluble. The descri
Externí odkaz:
https://doaj.org/article/2eb26bff2dc948e3abacc5552d6a6141
Autor:
Maria Helena VARELA
Publikováno v:
Reflexão, Vol 24, Iss 75 (2024)
A autora trata de caracterizar a racionalidade tal como se apresenta nos textos filosóficos e poéticos de língua portuguesa, centrando a discussão no conceito de heterologos, - pensamento impuro, entre o logos e o mythos, o poético e o profétic
Externí odkaz:
https://doaj.org/article/0f06d0bdb21c4d978cf11df8f7aaf587
Autor:
Maria Helena VARELA
Publikováno v:
Reflexão, Vol 24, Iss 73 (2024)
A relação poesia e filosofia nos dois grandes mestres do togocentrismo ocidental. Enquanto Platão, expulsando os poetas da cidade, definirá a poesia como uma mimesis infiel, arte dos simutacros, o poema aquém do materna e do filosofema, Aristót
Externí odkaz:
https://doaj.org/article/b3fa3570f1124ed8a207fb5d18757b3a
Publikováno v:
Electronic Journal of Differential Equations, Vol Special Issues, Iss 02, Pp 193-207 (2023)
Externí odkaz:
https://doaj.org/article/74fd06ac23b5421d80b494664cef619e
Autor:
Andrea Comba, Maria Luisa Varela, Syed M. Faisal, Clifford C. Abel, II, Anna E. Argento, Wajd N. Al-Holou, Todd C. Hollon, Jacqueline D. Perelman, Patrick J. Dunn, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102174- (2023)
Summary: Development of spatial-integrative pre-clinical models is needed for glioblastoma, which are heterogenous tumors with poor prognosis. Here, we present an optimized protocol to generate three-dimensional ex vivo explant slice glioma model fro
Externí odkaz:
https://doaj.org/article/2c43e2be55634ce0ab0275ab171a6f0b
Autor:
Andrea Comba, Syed M. Faisal, Patrick J. Dunn, Anna E. Argento, Todd C. Hollon, Wajd N. Al-Holou, Maria Luisa Varela, Daniel B. Zamler, Gunnar L. Quass, Pierre F. Apostolides, Clifford Abel, Christine E. Brown, Phillip E. Kish, Alon Kahana, Celina G. Kleer, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
It is essential to improve our understanding of the features that influence aggressiveness and invasion in high grade gliomas (HGG). Here, the authors characterize dynamic anatomical structures in HGG called oncostreams, which are associated with tum
Externí odkaz:
https://doaj.org/article/3b351a9de1174a41bae1168e3664c972
Autor:
Sarah Crestian Cunha, Fernanda Eid, Lucas Peiro, Maria Florencia Varela, Jose L. Peiro, Marcio Lopes Miranda
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 90, Iss , Pp 102554- (2023)
Human tails or caudal appendages are rare anomalies defined as lumbo-sacrococcygeal skin-covered appendages. They can be classified as true tails (vestigial structures containing normal tissues and not associated with other anomalies) or pseudo-tails
Externí odkaz:
https://doaj.org/article/61f4f1044fbb44bc8fcdcb9e6c346118
Autor:
Syed M. Faisal, Andrea Comba, Maria L. Varela, Anna E. Argento, Emily Brumley, Clifford Abel, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastoma (GBM), an aggressive high-grade glial tumor, is resistant to therapy and has a poor prognosis due to its universal recurrence rate. GBM cells interact with the non-cellular components in the tumor microenvironment (TME), facilitating the
Externí odkaz:
https://doaj.org/article/ab3ac9d856fb4768a00c709bfdd97349
Autor:
Andrea Franson, Brandon L. McClellan, Maria Luisa Varela, Andrea Comba, Mohammad Faisal Syed, Kaushik Banerjee, Ziwen Zhu, Nazareno Gonzalez, Marianela Candolfi, Pedro Lowenstein, Maria Graciela Castro
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The preclinical and clinical development of novel immunotherapies for the treatment of central nervous system (CNS) tumors is advancing at a rapid pace. High-grade gliomas (HGG) are aggressive tumors with poor prognoses in both adult and pediatric pa
Externí odkaz:
https://doaj.org/article/aa190e5206994038b0c0a18dd0e91df3