Alpha-catenin-dependent recruitment of the centrosomal protein CAP350 to adherens junctions allows epithelial cells to acquire a columnar shape.

Autor: Maria P Gavilan, Marina Arjona, Angel Zurbano, Etienne Formstecher, Juan R Martinez-Morales, Michel Bornens, Rosa M Rios

Publikováno v: PLoS Biology, Vol 13, Iss 3, p e1002087 (2015)

Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton. How this complex process is controlled at the molecular level is still largely unknown. Here, we report that the centrosomal microtubule (MT)-binding protein

Externí odkaz: https://doaj.org/article/8931271437e747d2be72f57d64e338ad

Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c

Autor: Antonio Díaz-Quintana, Rosa M. Ríos, Irene Díaz-Moreno, Miguel A. De la Rosa, Alejandro Velázquez-Cruz, Katiuska González-Arzola, Francisco Rivero-Rodríguez, Adrián Velázquez-Campoy, Maria P. Gavilan

Publikováno v: Redox Biology
Redox Biology, Vol 43, Iss, Pp 101967-(2021)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Digital.CSIC. Repositorio Institucional del CSIC

17 pags., 9 figs., 1 tab.
Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by Protein Phosphatase 2A (PP2A). Typical histone chaperones are the Acidic leucine-rich Nuclear Pho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff76eab6460b646f7099b403c216fe6
http://zaguan.unizar.es/record/112040

The dual role of the centrosome in organizing the microtubule network in interphase

Autor: Maria P. Gavilan, Michel Bornens, Rosa M. Ríos, Fernando R. Balestra, Francisco Arias, Pablo Gandolfo

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Here, we address the regulation of microtubule nucleation during interphase by genetically ablating one, or two, of three major mammalian γ‐TuRC‐binding factors namely pericentrin, CDK5Rap2, and AKAP450. Unexpectedly, we find that while all of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192b5d5ae3532e2f798ba2880cb4b07d
https://pubmed.ncbi.nlm.nih.gov/30224411

The Centrosome Controls the Number and Spatial Distribution of Microtubules by Negatively Regulating Alternative MTOCs

Autor: Francisco Arias, Pablo Gandolfo, Fernando R. Balestra, Rosa M. Ríos, Maria P. Gavilan, Michel Bornens

In this work, we have investigated in mammalian cells how microtubule nucleation at centrosome and Golgi apparatus are coordinated, using genetic ablation of three γ-TuRC binding proteins -AKAP450, Pericentrin and CDK5Rap2- and the PLK4 inhibitor ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e28845513ee8502e44c5d64bd0119f4

Link between Cell Junctions and Microtubule Cytoskeleton Is Critical for Epithelial Morphogenesis

Autor: Juan Ramón Martínez-Morales, Michel Bornens, Ángel Zurbano, Maria P. Gavilan, Rosa M. Ríos, Marina Arjona, Etienne Formstecher

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Biology, Vol 13, Iss 3, p e1002087 (2015)
PLoS Biology

Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton. How this complex process is controlled at the molecular level is still largely unknown. Here, we report that the centrosomal microtubule (MT)-binding protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3362000114d0dfb785384bf2d7c0f364
http://hdl.handle.net/10261/123668