Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maria P Blasco-Conesa"'
Autor:
Maria P. Blasco Conesa, Frank W. Blixt, Pedram Peesh, Romeesa Khan, Janelle Korf, Juneyoung Lee, Gayathri Jagadeesan, Alexander Andersohn, Tushar K. Das, Chunfeng Tan, Claudia Di Gesu, Gabriela Delevati Colpo, Jose Félix Moruno-Manchón, Louise D. McCullough, Robert Bryan, Bhanu P. Ganesh
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract Stroke is the most common cause of long-term disability and places a high economic burden on the global healthcare system. Functional outcomes from stroke are largely determined by the extent of ischemic injury, however, there is growing rec
Externí odkaz:
https://doaj.org/article/a01c98fa47ff4cffb5d68a961eb269c6
Autor:
Pedram Honarpisheh, Juneyoung Lee, Anik Banerjee, Maria P. Blasco-Conesa, Parisa Honarpisheh, John d’Aigle, Abdullah A. Mamun, Rodney M. Ritzel, Anjali Chauhan, Bhanu P. Ganesh, Louise D. McCullough
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background The ability to distinguish resident microglia from infiltrating myeloid cells by flow cytometry-based surface phenotyping is an important technique for examining age-related neuroinflammation. The most commonly used surface marker
Externí odkaz:
https://doaj.org/article/d8172234ec4a413297ce211b0f9dd08d
Autor:
Brian Noh, Maria P. Blasco-Conesa, Yun-Ju Lai, Bhanu Priya Ganesh, Akihiko Urayama, Ines Moreno-Gonzalez, Sean P. Marrelli, Louise D. McCullough, Jose Felix Moruno-Manchon
Publikováno v:
Frontiers in Aging, Vol 2 (2022)
Senescence in the cerebral endothelium has been proposed as a mechanism that can drive dysfunction of the cerebral vasculature, which precedes vascular dementia. Cysteine-rich angiogenic inducer 61 (Cyr61/CCN1) is a matricellular protein secreted by
Externí odkaz:
https://doaj.org/article/6c4b12423416476bb2ad2cf9f5bf97fa
Autor:
Janelle M. Korf, Pedram Honarpisheh, Eric C. Mohan, Anik Banerjee, Maria P. Blasco-Conesa, Parisa Honarpisheh, Gary U. Guzman, Romeesa Khan, Bhanu P. Ganesh, Amy L. Hazen, Juneyoung Lee, Aditya Kumar, Louise D. McCullough, Anjali Chauhan
Publikováno v:
The Journal of Immunology. 209:288-300
Recent studies have highlighted the deleterious contributions of B cells to post-stroke recovery and cognitive decline. Different B cell subsets have been proposed on the basis of expression levels of transcription factors (e.g., T-bet) as well as sp
Autor:
Pedram Honarpisheh, Caroline R. Reynolds, Maria P. Blasco Conesa, Jose F. Moruno Manchon, Nagireddy Putluri, Meenakshi B. Bhattacharjee, Akihiko Urayama, Louise D. McCullough, Bhanu P. Ganesh
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1711 (2020)
Amyloid plaques in Alzheimer’s disease (AD) are associated with inflammation. Recent studies demonstrated the involvement of the gut in cerebral amyloid-beta (Aβ) pathogenesis; however, the mechanisms are still not well understood. We hypothesize
Externí odkaz:
https://doaj.org/article/1a74b020f6a54b9283e7c76bc0cc5c4b
Autor:
Tushar K. Das, Maria P. Blasco-Conesa, Janelle Korf, Pedram Honarpisheh, Matthew R. Chapman, Bhanu P. Ganesh
Publikováno v:
J Alzheimers Dis
Background: Substantial evidence from recent research suggests an influential and underappreciated force in Alzheimer’s disease (AD) pathogenesis: the pathological signals originate from outside the brain. Pathogenic bacteria produce amyloid-like p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33ed93794f2f5d6203125b029b2a423
https://doi.org/10.3233/aiad220010
https://doi.org/10.3233/aiad220010
Autor:
William W. Won, Frank Blixt, Pedram Honarpisheh, Bhanu P. Ganesh, J. Weldon Furr, Robert M. Bryan, Jacob Hudobenko, Louise D. McCullough, Alexis S. Mobley, Katherine E. Brannick, M.S.D.V.M. Liang Zhu, Yashasvee Munshi, Amy L. Hazen, Maria P. Blasco Conesa, M.S. Juneyoung Lee, John d'Aigle
Publikováno v:
Brain Behav Immun
Aging is associated with dysfunction of the gut microbiota-immune-brain axis, a major regulatory axis in both brain health and in central nervous system (CNS) diseases. Antigen presenting cells (APCs) play a major role in sensing changes in the gut m
Autor:
Janelle Korf, Anna St Denis, Pedram Honarpisheh, Anik Banerjee, Eric Mohan, Frank Blixt, Romana Sharmeen, Juneyoung Lee, Maria P Blasco-Conesa, Louise McCullough, Bhanu P Ganesh
Publikováno v:
Stroke. 53
Introduction: Neonatal Hypoxic Ischemic Encephalopathy (nHIE) is a major cause of mortality and morbidity in infants, occurring in 1.5/1000 live births. Inflammation persists years after injury and detrimentally affects neurocognitive outcomes in chi
Autor:
Janelle Korf, Pedram Honarpisheh, Eric Mohan, Anik Banerjee, Maria P Blasco-Conesa, Mian Ahmad, Bhanu P Ganesh, Amy Hazen, Juneyoung Lee, Aditya Kumar, Louise McCullough, Anjali Chauhan
Publikováno v:
Stroke. 53
CD11b expression is essential for immunity due to its role in cell motility and phagocytosis. Leukocytes, including monocytes, neutrophils and macrophages, express CD11b. B lymphocytes, which are both adaptive immune cells and antigen presenting cell
Autor:
Maria P Blasco-Conesa, Frank Blixt, Pedram Honarpisheh, Janelle Korf, Juneyoung Lee, Louise McCullough, Anik Banerjee, Bhanu P Ganesh
Publikováno v:
Stroke. 53
Background: Clinically, ~65% of stroke patients are left with functional impairments after stroke and 15% die shortly after their stroke. Increasing evidence suggests that peripheral inflammatory responses after stroke play an important role in deter