Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Maria Ormhøj"'
Autor:
Marco Donia, Özcan Met, Julie Westerlin Kjeldsen, Sine Reker Hadrup, Inge Marie Svane, Arianna Draghi, Anders Handrup Kverneland, Christina Heeke, Siri Amanda Tvingsholm, Marcus Svensson Frej, Vibeke Mindahl Rafa, Ulla Kring Hansen, Maria Ormhøj, Alexander Tyron, Agnete W P Jensen, Mohammad Kadivar, Amalie Kai Bentzen, Kamilla K Munk, Gitte N Aasbjerg, Jeppe S H Ternander, Tripti Tamhane, Christian Schmess, Samuel A. Funt, Søren Nyboe Jakobsen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Adoptive cell therapy (ACT) has shown promising results for the treatment of cancer and viral infections. Successful ACT relies on ex vivo expansion of large numbers of desired T-cells with strong cytotoxic capacity and in vivo persistence
Externí odkaz:
https://doaj.org/article/a25dad34aae2492e8875e883c1894921
Autor:
Marcela V. Maus, Matthew J. Frigault, Torben Barington, David M. Weinstock, Henrik J. Ditzel, Morten F. Gjerstorff, Jacob H. Christensen, Charlotte G. Nyvold, Oriane Cédile, Rikke S. Andersen, Bryan D. Choi, Andrea Schmidts, Lauren S. Riley, Rebecca C. Larson, Ana P. Castano, Amanda A. Bouffard, Selena J. Lorrey, Stefanie R. Bailey, Maria L. Cabral, Irene Scarfò, Maria Ormhøj
Supplementary Materials and Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4582e5857ca892ad3132a1732e1514a3
https://doi.org/10.1158/1078-0432.22471292.v1
https://doi.org/10.1158/1078-0432.22471292.v1
Autor:
Marcela V. Maus, Matthew J. Frigault, Torben Barington, David M. Weinstock, Henrik J. Ditzel, Morten F. Gjerstorff, Jacob H. Christensen, Charlotte G. Nyvold, Oriane Cédile, Rikke S. Andersen, Bryan D. Choi, Andrea Schmidts, Lauren S. Riley, Rebecca C. Larson, Ana P. Castano, Amanda A. Bouffard, Selena J. Lorrey, Stefanie R. Bailey, Maria L. Cabral, Irene Scarfò, Maria Ormhøj
Purpose:T cells engineered to express a chimeric antigen receptor (CAR) against CD19 have recently been FDA approved for the treatment of relapsed or refractory large B-cell lymphoma. Despite the success and curative potential of CD19 CAR T cells, se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1dd747a9509cb3fb9a52f5ceb15ca80
https://doi.org/10.1158/1078-0432.c.6527840.v1
https://doi.org/10.1158/1078-0432.c.6527840.v1
Autor:
Amanda A. Bouffard, Kenneth C. Anderson, Lauren S. Riley, Bryan D. Choi, Ana P. Castano, Rebecca C. Larson, Wolfgang W. A. Schamel, Yu-Tzu Tai, Matthew J. Frigault, Andrea Schmidts, Marcela V. Maus, Sean G Mackay, Maria Ormhøj, Maria L. Cabral, Rubí M.-H. Velasco Cárdenas, Jing Zhou, Irene Scarfò, Kathleen Gallagher, Angela C. Boroughs, Allison Taylor
Publikováno v:
Schmidts, A, Ormhøj, M, Choi, B D, Taylor, A O, Bouffard, A A, Scarfò, I, Larson, R C, Frigault, M J, Gallagher, K, Castano, A P, Riley, L S, Cabral, M L, Boroughs, A C, Velasco Cárdenas, R M H, Schamel, W, Zhou, J, Mackay, S, Tai, Y T, Anderson, K C & Maus, M V 2019, ' Rational design of a trimeric April-based CAR-binding domain enables efficient targeting of multiple myeloma ', Blood Advances, vol. 3, no. 21, pp. 3248-3260 . https://doi.org/10.1182/bloodadvances.2019000703
Chimeric antigen receptor (CAR) T cells (CARTs) have shown tremendous potential for the treatment of certain B-cell malignancies, including patients with relapsed/refractory multiple myeloma (MM). Targeting the B-cell maturation antigen (BCMA) has pr
Autor:
Matthew J. Frigault, Scott J. Rodig, Alexandra J. Shay, Ana P. Castano, Alexandria Van Scoyk, Maria Ormhøj, Frederic I. Preffer, David M. Weinstock, Irene Scarfò, Jon C. Aster, Marcela V. Maus, Selena J. Lorrey, Amanda A. Bouffard
Publikováno v:
Scarfò, I, Ormhøj, M, Frigault, M J, Castano, A P, Lorrey, S, Bouffard, A A, Van Scoyk, A, Rodig, S J, Shay, A J, Aster, J C, Preffer, F I, Weinstock, D M & Maus, M V 2018, ' Anti-CD37 chimeric antigen receptor T cells are active against B-A nd T-cell lymphomas ', Blood, vol. 132, no. 14, pp. 1495-1506 . https://doi.org/10.1182/blood-2018-04-842708
Chimeric antigen receptor (CAR) T cells have emerged as a novel form of treatment of patients with B-cell malignancies. In particular, anti-CD19 CAR T-cell therapy has effected impressive clinical responses in B-cell acute lymphoblastic leukemia and
Publikováno v:
Nielsen, A Y, Ormhøj, M, Traynor, S & Gjerstorff, M F 2020, ' Augmenting engineered T-cell strategies in solid cancers through epigenetic priming ', Cancer Immunology, Immunotherapy, vol. 69, pp. 2169–2178 . https://doi.org/10.1007/s00262-020-02661-1
Nielsen, A Y, Ormhøj, M, Traynor, S & Gjerstorff, M F 2020, ' Augmenting engineered T-cell strategies in solid cancers through epigenetic priming ', Cancer Immunology, Immunotherapy, vol. 69, no. 11, pp. 2169-2178 . https://doi.org/10.1007/s00262-020-02661-1
Nielsen, A Y, Ormhøj, M, Traynor, S & Gjerstorff, M F 2020, ' Augmenting engineered T-cell strategies in solid cancers through epigenetic priming ', Cancer Immunology, Immunotherapy, vol. 69, no. 11, pp. 2169-2178 . https://doi.org/10.1007/s00262-020-02661-1
T-cell receptor (TCR)- and chimeric antigen receptor (CAR)-based adoptive cell transfer (ACT) has shown promising results in hematological malignancies, but remains immature in solid cancers. The challenges associated with identification of tumor-spe
Autor:
Matthew J. Frigault, Rikke Sick Andersen, Charlotte Guldborg Nyvold, Irene Scarfò, Morten F. Gjerstorff, Selena J. Lorrey, Andrea Schmidts, Marcela V. Maus, Oriane Cédile, Amanda A. Bouffard, Henrik J. Ditzel, Lauren S. Riley, Maria L. Cabral, Maria Ormhøj, David M. Weinstock, Stefanie R. Bailey, Torben Barington, Rebecca C. Larson, Jacob Haaber Christensen, Bryan D. Choi, Ana P. Castano
Publikováno v:
Clin Cancer Res
Ormhøj, M, Scarfò, I, Cabral, M L, Bailey, S R, Lorrey, S J, Bouffard, A A, Castano, A P, Larson, R C, Riley, L S, Schmidts, A, Choi, B D, Andersen, R S, Cédile, O, Nyvold, C G, Haaber, J, Gjerstorff, M F, Ditzel, H J, Weinstock, D M, Barington, T, Frigault, M J & Maus, M V 2019, ' Chimeric Antigen Receptor T Cells Targeting CD79b Show Efficacy in Lymphoma with or without Cotargeting CD19 ', Clinical Cancer Research, vol. 25, no. 23, pp. 7046-7057 . https://doi.org/10.1158/1078-0432.CCR-19-1337
Ormhøj, M, Scarfò, I, Cabral, M L, Bailey, S R, Lorrey, S J, Bouffard, A A, Castano, A P, Larson, R C, Riley, L S, Schmidts, A, Choi, B D, Andersen, R S, Cédile, O, Nyvold, C G, Haaber, J, Gjerstorff, M F, Ditzel, H J, Weinstock, D M, Barington, T, Frigault, M J & Maus, M V 2019, ' Chimeric Antigen Receptor T Cells Targeting CD79b Show Efficacy in Lymphoma with or without Cotargeting CD19 ', Clinical Cancer Research, vol. 25, no. 23, pp. 7046-7057 . https://doi.org/10.1158/1078-0432.CCR-19-1337
PURPOSE: T cells engineered to express a chimeric antigen receptor (CAR) against CD19 have recently been FDA-approved for the treatment of relapsed or refractory large B cell lymphoma. Despite the success and curative potential of CD19 CAR T cells, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0343f4be45aa193077097c36ef8b53
https://europepmc.org/articles/PMC6891163/
https://europepmc.org/articles/PMC6891163/
Autor:
Torben Barington, Maria Ormhøj
Publikováno v:
Barington, T & Ormhøj, M 2018, ' Emerging Cellular Therapies: T Cells and Beyond (B6) ', Keystone Symposia Conference, Keystone, Colorado, USA, Colorado, United States, 10/02/2018-16/02/2018 .
University of Southern Denmark
University of Southern Denmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5e76dfc3f846841bf6148f4140bef888
https://portal.findresearcher.sdu.dk/da/publications/d3930bda-9250-4c31-bdcc-299906213d0b
https://portal.findresearcher.sdu.dk/da/publications/d3930bda-9250-4c31-bdcc-299906213d0b
Publikováno v:
Ormhøj, M, Bedoya, F, Frigault, M J & Maus, M V 2017, ' CARs in the Lead Against Multiple Myeloma ', Current Hematologic Malignancy Reports, vol. 12, no. 2, pp. 119–125 . https://doi.org/10.1007/s11899-017-0373-2
The recent clinical success of CD19-directed chimeric antigen receptor (CAR) T cell therapy in chronic and acute leukemia has led to increased interest in broadening this technology to other hematological malignancies and solid tumors. Now, advances
Autor:
Bettina Hjelm Clausen, Yvonne Couch, Christine Kring, Maja Møller, Kate Lykke Lambertsen, Maria Ormhøj, Maria Gammelstrup Andersen
Publikováno v:
F1000Research. 7:1430
Background:Stroke is a devastating neurological injury, which can result in significant cognitive and behavioural deficits. Modelling the disease processes associated with stroke in animals is key to the development of novel therapeutic approaches. H