The Sirolimus-Eluting Cypher Select Coronary Stent for the Treatment of Bare-Metal and Drug-Eluting Stent Restenosis

Autor: Philip Urban, Runlin Gao, Alexandre Abizaid, Franz-Josef Neumann, Stephen G. Ellis, Maria Nyakern, Stephen G. Worthley, Vladimir Dzavik, David R. Holmes, Adrian P. Banning, Victor Legrand, Christian Spaulding, J. Ribamar Costa, Amy Orlick, Antonio L. Bartorelli, Muyng Ho Jeong

Publikováno v: JACC: Cardiovascular Interventions. 5(1):64-71

Objectives This study sought to compare the 1-year safety and efficacy of Cypher Select or Cypher Select Plus (Cordis Corporation, Bridgewater, New Jersey) sirolimus-eluting stents (SES) with the treatment of bare-metal stents (BMS) and drug-eluting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d2386ab408ed6f37e220dc58861135

The Phosphoinositide 3-Kinase (PI3K)/AKT Signaling Pathway as a Therapeutic Target for the Treatment of Human Acute Myeloid Leukemia (AML)

Autor: Roberta Bortul, Maria Nyakern, Camilla Evangelisti, Pier Luigi Tazzari, Lucio Cocco, Alberto M. Martelli, Giovanna Tabellini

Publikováno v: Current Signal Transduction Therapy. 2:246-256

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6191da028c20b826992c829e2fc9d697
https://doi.org/10.2174/157436207781745373

Stent thrombosis and bleeding complications after implantation of sirolimus-eluting coronary stents in an unselected worldwide population: a report from the e-SELECT (Multi-Center Post-Market Surveillance) registry

Autor: Philip, Urban, Alexandre, Abizaid, Adrian, Banning, Antonio L, Bartorelli, Ana Cebrian, Baux, Vladimír, Džavík, Stephen, Ellis, Runlin, Gao, David, Holmes, Myung Ho, Jeong, Victor, Legrand, Franz-Josef, Neumann, Maria, Nyakern, Christian, Spaulding, Stephen, Worthley, Andres, Lairet

Publikováno v: Journal of the American College of Cardiology. 57(13)

The aim of this study was to ascertain the 1-year incidence of stent thrombosis (ST) and major bleeding (MB) in a large, unselected population treated with sirolimus-eluting stents (SES).Stent thrombosis and MB are major potential complications of dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78f174576f4104af0ad82a62e594d89f
https://pubmed.ncbi.nlm.nih.gov/21435513

Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia

Autor: P. L. Tazzari, Roberta Bortul, Camilla Evangelisti, Maria Nyakern, Giovanna Tabellini, Am Martelli, Lucio Cocco

Publikováno v: Leukemia 20:6 (2006): 911–928.
info:cnr-pdr/source/autori:A.M. MARTELLI, M. NYAKERN, G. TABELLINI, R. BORTUL, P.L. TAZZARI, C. EVANGELISTI, L. COCCO,/titolo:Phosphoinositide 3-kinase%2FAkt signaling pathway and its therapeutical implications for human acute myeloid leukaemia,/doi:/rivista:Leukemia/anno:2006/pagina_da:911/pagina_a:928/intervallo_pagine:911–928/volume:20:6

The phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is crucial to many aspects of cell growth, survival and apoptosis, and its constitutive activation has been implicated in the both the pathogenesis and the progression of a wide variety of ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4a486e434b6d96e736e58051437748
https://pubmed.ncbi.nlm.nih.gov/16642045

Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways

Autor: Alberto M. Martelli, Irina Mantovani, Maria Nyakern, Alessandra Cappellini

Publikováno v: Molecular cancer therapeutics 5:6 (2006): 1559–1570.
info:cnr-pdr/source/autori:M. NYAKERN, A. CAPPELLINI, I. MANTOVANI, A.M. MARTELLI,/titolo:Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways,/doi:/rivista:Molecular cancer therapeutics/anno:2006/pagina_da:1559/pagina_a:1570/intervallo_pagine:1559–1570/volume:5:6

Perifosine is an Akt inhibitor displaying strong antineoplastic effects in human tumor cell lines and is currently being tested in phase II clinical trials for treatment of major human cancers. Several recent studies showed the apoptotic effect of pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e771ee0d58daac44ef2c9ffe9a465f
http://hdl.handle.net/11580/9824