Výsledky vyhledávání - "Maria Noelia Chao"

Akademický článek

A Convenient Route to New (Radio)Fluorinated and (Radio)Iodinated Cyclic Tyrosine Analogs

Autor: Maria Noelia Chao, Jean-Michel Chezal, Eric Debiton, Damien Canitrot, Tiffany Witkowski, Sophie Levesque, Françoise Degoul, Sébastien Tarrit, Barbara Wenzel, Elisabeth Miot-Noirault, Audrey Serre, Aurélie Maisonial-Besset

Publikováno v: Pharmaceuticals, Vol 15, Iss 2, p 162 (2022)

The use of radiolabeled non-natural amino acids can provide high contrast SPECT/PET metabolic imaging of solid tumors. Among them, radiohalogenated tyrosine analogs (i.e., [123I]IMT, [18F]FET, [18F]FDOPA, [123I]8-iodo-L-TIC(OH), etc.) are of particul

Externí odkaz: https://doaj.org/article/939943005baa4438ab347be942640403

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Synthetic and Mechanistic Studies on 2,3-Dihydrobenzo[b][1,4]-oxaselenines Formation from Selenocyanates

Autor: Sergio M. Bonesi, Jonathan Sánchez González, Sergio H. Szajnman, Mauricio Cattaneo, Maria Noelia Chao, Juan B. Rodriguez

Publikováno v: Synthesis. 52:1643-1658

An expedient preparation of selenium-containing heterocycles via an m-chloroperbenzoic acid-mediated seleno-annulation starting from selenocyanate derivatives is described. In spite of its significance, this cyclization reaction is virtually unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::831065788f682c1b6e39f6a47047c603
https://doi.org/10.1055/s-0039-1690800

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Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors ofTrypanosoma cruziandToxoplasma gondii

Autor: Juan B. Rodriguez, Melissa Storey, Roberto Docampo, Catherine Li, Sergio H. Szajnman, Carolina Exeni Matiuzzi, Maria Noelia Chao, Silvia N.J. Moreno

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

As a part of our project aimed at searching new safe chemotherapeutic agents against parasitic diseases, several compounds structurally related to the antiparasitic agent WC-9 (4-phenoxyphenoxyethyl thiocyanate), which were modified at the terminal p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8f66ef347890a7088d3add1658b800
https://doi.org/10.1002/cmdc.201500100

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Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents

Autor: Pablo Damián Elicio, Silvia N.J. Moreno, Juan B. Rodriguez, Melina Galizzi, Catherine Li, Sergio H. Szajnman, Maria Noelia Chao, Roberto Docampo

Publikováno v: European Journal of Medicinal Chemistry. 69:480-489

As a part of our project pointed at the search of new safe chemotherapeutic and chemoprophylactic agents against parasitic diseases, several compounds structurally related to 4-phenoxyphenoxyethyl thiocyanate (WC-9), which were modified at the termin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63988db30ec1ae1ab795340f4a47e94d
https://doi.org/10.1016/j.ejmech.2013.09.009

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Activity of Fluorine-Containing Analogues of WC-9 and Structurally Related Analogues against Two Intracellular Parasites: Trypanosoma cruzi and Toxoplasma gondii

Autor: Silvia N.J. Moreno, Sergio M. Bonesi, Melissa Storey, Sergio H. Szajnman, Roberto Docampo, Maria Noelia Chao, Juan B. Rodriguez, Catherine Li, Bruno Nicolas Falcone

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Two obligate intracellular parasites, Trypanosoma cruzi, the agent of Chagas disease, and Toxoplasma gondii, an agent of toxoplasmosis, upregulate the mevalonate pathway of their host cells upon infection, which suggests that this host pathway could

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41b1142e459fa1e5ba8769e1d209ae1
Wiley Online Library

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In Vitro and In Vivo Activities of Sulfur-Containing Linear Bisphosphonates against Apicomplexan Parasites

Autor: Zhu-Hong Li, Silvia N.J. Moreno, Catherine Li, Boris Striepen, Nathan M. Howell, Maria Noelia Chao, Tamila Pavlivna Galaka, Sergio H. Szajnman, Juan B. Rodriguez, Vasant Muralidharan

Publikováno v: Antimicrobial agents and chemotherapy. 61(2)

We tested a series of sulfur-containing linear bisphosphonates against Toxoplasma gondii , the etiologic agent of toxoplasmosis. The most potent compound (compound 22; 1-[( n -decylsulfonyl)ethyl]-1,1-bisphosphonic acid) is a sulfone-containing compo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee1b32a9f4021a91e0530c65bf5f348
https://pubmed.ncbi.nlm.nih.gov/27895021

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