Reduced plasma amino acid levels during allogeneic haematopoietic stem cell transplantation are associated with systemic inflammation and treatment-related complications

Autor: Christian Mølgaard, Douglas G. Burrin, Katrine Kielsen, Carsten Heilmann, Klaus Müller, Maria Nederby, Henrik Sengeløv, Marianne Ifversen, Lotte Schmidt, Sarah Weischendorff

Publikováno v: Weischendorff, S, Kielsen, K, Nederby, M, Schmidt, L, Burrin, D, Heilmann, C, Ifversen, M, Sengeløv, H, Mølgaard, C & Müller, K 2019, ' Reduced plasma amino acid levels during allogeneic haematopoietic stem cell transplantation are associated with systemic inflammation and treatment-related complications ', Biology of Blood and Marrow Transplantation, vol. 25, no. 7, pp. 1432-1440 . https://doi.org/10.1016/j.bbmt.2019.03.018

Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) are challenged by cytotoxic effects of the conditioning regimen, resulting in tissue damage, systemic inflammation, and increased metabolic demands for amino acids to regen

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