Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Maria Mudryj"'
Autor:
Thomas M. Steele, Maria Malvina Tsamouri, Salma Siddiqui, Christopher A. Lucchesi, Demitria Vasilatis, Benjamin A. Mooso, Blythe P. Durbin-Johnson, Ai-Hong Ma, Nazila Hejazi, Mamta Parikh, Maria Mudryj, Chong-xian Pan, Paramita M. Ghosh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cisplatin-based combination chemotherapy is the foundation for treatment of advanced bladder cancer (BlCa), but many patients develop chemoresistance mediated by increased Akt and ERK phosphorylation. However, the mechanism by which cisplati
Externí odkaz:
https://doaj.org/article/e7fd4fc41429405c9cbe1caf0f8d8467
Autor:
Kimberley D. Katleba, Maria-Malvina Tsamouri, Maitreyee Jathal, Han Bit Baek, Rebecca B. Armenta, Clifford G. Tepper, Gino Cortopassi, Paramita M. Ghosh, Maria Mudryj
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The observed sex disparity in bladder cancer (BlCa) argues that androgen receptor (AR) signaling has a role in these malignancies. BlCas express full-length AR (FL-AR), constitutively active AR splice variants, including AR-v19, or both, and
Externí odkaz:
https://doaj.org/article/808e9dbfa3f84e6190abe7c760f86466
Autor:
Maria Mudryj, Paramita M. Ghosh
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/6881b847bc1d458687d999671dca8dd6
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2215 (2023)
Multiple studies have demonstrated the importance of androgen receptor (AR) splice variants (SVs) in the progression of prostate cancer to the castration-resistant phenotype and their utility as a diagnostic. However, studies on AR expression in non-
Externí odkaz:
https://doaj.org/article/c2ab9bea70ea4ba08174cddca8a6000c
Autor:
Christopher A. Lucchesi, Demitria M. Vasilatis, Saisamkalpa Mantrala, Thenappan Chandrasekar, Maria Mudryj, Paramita M. Ghosh
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11395 (2023)
Multiple risk factors have been associated with bladder cancer. This review focuses on pesticide exposure, as it is not currently known whether agricultural products have a direct or indirect effect on bladder cancer, despite recent reports demonstra
Externí odkaz:
https://doaj.org/article/2b6586a30b57449a9a096501cd5778a0
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1472 (2021)
Muscle-invasive urothelial carcinoma (MIUC) is the most common type of bladder malignancy in humans, but also in dogs that represent a naturally occurring model for this disease. Dogs are immunocompetent animals that share risk factors, pathophysiolo
Externí odkaz:
https://doaj.org/article/8a27dff416884503974f69929aa40da8
Autor:
Elisabeth A. Messner, Thomas M. Steele, Maria Malvina Tsamouri, Nazila Hejazi, Allen C. Gao, Maria Mudryj, Paramita M. Ghosh
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 422 (2020)
The androgen receptor (AR) plays a predominant role in prostate cancer (PCa) pathology. It consists of an N-terminal domain (NTD), a DNA-binding domain (DBD), a hinge region (HR), and a ligand-binding domain (LBD) that binds androgens, including test
Externí odkaz:
https://doaj.org/article/35004da794404d229d70334322341d91
Publikováno v:
Genes & cancer, vol 11, iss 1-2
Genes & Cancer
Genes & Cancer
While many genes specifically act as oncogenes or tumor suppressors, others are tumor promoters or suppressors in a context-dependent manner. Here we will review the basic-helix-loop-helix (BHLH) protein BHLHE40, (also known as BHLHB2, STRA13, DEC1,
Publikováno v:
Biomedicines, vol 9, iss 10
Biomedicines
Biomedicines, Vol 9, Iss 1472, p 1472 (2021)
Biomedicines
Biomedicines, Vol 9, Iss 1472, p 1472 (2021)
Muscle-invasive urothelial carcinoma (MIUC) is the most common type of bladder malignancy in humans, but also in dogs that represent a naturally occurring model for this disease. Dogs are immunocompetent animals that share risk factors, pathophysiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4451806059ab93d9c05c120d3dc674a2
https://escholarship.org/uc/item/8cd6j0zx
https://escholarship.org/uc/item/8cd6j0zx
Autor:
Alexander J. Platero, Alan P. Lombard, Maria Mudryj, Paramita M. Ghosh, Ai Hong Ma, Stephen J. Libertini, Kristine S. Nishida, Chong-Xian Pan, Kimberley Katleba, Han Bit Baek, Maria Malvina Tsamouri
Publikováno v:
Cancer Lett
Bladder cancer (BlCa) exhibits a gender disparity where men are three times more likely to develop the malignancy than women suggesting a role for the androgen receptor (AR). Here we report that BlCa cells express low molecular weight (LMW) AR isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df581cc7afca6041c7c65a9f5c7d94fb
https://escholarship.org/uc/item/5rn509g0
https://escholarship.org/uc/item/5rn509g0