Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maria Michelle Fernando"'
Autor:
Timothy W. Behrens, Adam J. de Smith, Lachlan J. M. Coin, Alexandra I. F. Blakemore, Maria Michelle Fernando, David L. Morris, Jonathan Mangion, Timothy J. Vyse, Philippe Froguel, Robert R. Graham
Publikováno v:
Annals of Human Genetics. 75:383-397
We undertook a candidate locus study of the HIN200 gene cluster on 1q21-23 in UK systemic lupus erythematosus (SLE) families. To date, despite mounting evidence demonstrating the importance of these proteins in autoimmune disease, cancer, apoptosis,
Publikováno v:
Rheumatology. 45:1062-1067
Defining the polymorphisms that contribute to the development of complex genetic disease traits is a challenging, although increasingly tractable problem. Historically, the technical difficulties in conducting association studies across the entire hu
Publikováno v:
British Journal of Dermatology. 147:554-557
Treatment of recalcitrant psoriasis and psoriatic arthritis can be challenging, with treatment options limited by drug intolerance or poor efficacy. High-dose intravenous immunoglobulin (hdIVIg) has been used successfully in Kawasaki's disease and id
Lateral medullary syndrome with anti-neuronal antibodies (anti-Ta/Ma2) in primary Sjogren's syndrome
Autor:
Sophie Molloy, Maria Michelle Fernando, Puja K. Mehta, C Bernard Colaço, Yannoulla Wilson, Matthew C. Pickering
Publikováno v:
Rheumatology. 48:1174-1176
Publisher Summary Human leukocyte antigen (HLA) class I and class II molecules are critical in mediating host defense responses through antigen presentation and immune tolerance by means of self/non-self recognition. Major histocompatibility complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72658408f1e64910ab0552b680c0285b
https://doi.org/10.1016/b978-0-12-374994-9.10001-4
https://doi.org/10.1016/b978-0-12-374994-9.10001-4
Publikováno v:
Annals of the Rheumatic Diseases. 74:75.2-75
Background Systemic lupus erythematosus (SLE) is a complex genetic autoimmune disease characterised by B cell hyperactivity and up-regulation of type I IFN. The DRB1*03:01 extended haplotype confers the greatest genetic risk for SLE in Europeans, but
Autor:
David L. Morris, Javier Martín, Josefina Cortés-Hernández, Lora Boteva, Timothy J. Vyse, Maria Michelle Fernando
Publikováno v:
The American Journal of Human Genetics. (3):445-456
Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease. Complete deficiency of complement component C4 confers strong genetic risk for SLE. Partial C4 deficiency states have also shown association with SLE, but despite much e