Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Maria Michelina Raso"'
Autor:
Giampiero Batani, Giacomo Vezzani, Sabrina Lashchuk, Abdelmounaaim Allaoui, Dario Cardamone, Maria Michelina Raso, Elena Boero, Emanuele Roscioli, Matteo Ridelfi, Gianmarco Gasperini, Mariagrazia Pizza, Omar Rossi, Francesco Berlanda Scorza, Francesca Micoli, Rino Rappuoli, Claudia Sala
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionShigella is the etiologic agent of a bacillary dysentery known as shigellosis, which causes millions of infections and thousands of deaths worldwide each year due to Shigella’s unique lifestyle within intestinal epithelial cells. Cell a
Externí odkaz:
https://doaj.org/article/c47a2121f1054a28836f50d00d418ed9
Autor:
Omar Rossi, Francesco Citiulo, Carlo Giannelli, Emilia Cappelletti, Gianmarco Gasperini, Francesca Mancini, Alessandra Acquaviva, Maria Michelina Raso, Luigi Sollai, Renzo Alfini, Maria Grazia Aruta, Claudia Giorgina Vitali, Mariagrazia Pizza, Francesca Necchi, Rino Rappuoli, Laura B. Martin, Francesco Berlanda Scorza, Anna Maria Colucci, Francesca Micoli
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Shigellosis is a leading cause of diarrheal disease in low-middle-income countries (LMICs). Effective vaccines will help to reduce the disease burden, exacerbated by increasing antibiotic resistance, in the most susceptible population repres
Externí odkaz:
https://doaj.org/article/8f06585515e04904964eb15408b696d7
Autor:
Rebecca Nappini, Renzo Alfini, Salvatore Durante, Laura Salvini, Maria Michelina Raso, Elena Palmieri, Roberta Di Benedetto, Martina Carducci, Omar Rossi, Paola Cescutti, Francesca Micoli, Carlo Giannelli
Publikováno v:
Vaccines, Vol 12, Iss 7, p 707 (2024)
Glycoconjugation is a well-established technology for vaccine development: linkage of the polysaccharide (PS) antigen to an appropriate carrier protein overcomes the limitations of PS T-independent antigens, making them effective in infants and provi
Externí odkaz:
https://doaj.org/article/55affb9a06504de7ac9d8c53e73d826c
Autor:
Gianmarco Gasperini, Luisa Massai, Daniele De Simone, Maria Michelina Raso, Elena Palmieri, Renzo Alfini, Omar Rossi, Neil Ravenscroft, Michelle M. Kuttel, Francesca Micoli
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionDifferent serovars of Salmonella enterica cause systemic diseases in humans including enteric fever, caused by S. Typhi and S. Paratyphi A, and invasive nontyphoidal salmonellosis (iNTS), caused mainly by S. Typhimurium and S. Enteritidis
Externí odkaz:
https://doaj.org/article/35cad51a0ebe43bea77726b50d883391
Autor:
Francesca Nonne, Mariagrazia Molfetta, Rebecca Nappini, Chiara La Guidara, Roberta Di Benedetto, Siwaphiwe Mfana, Barbara Bellich, Maria Michelina Raso, Gianmarco Gasperini, Renzo Alfini, Paola Cescutti, Francesco Berlanda Scorza, Neil Ravenscroft, Francesca Micoli, Carlo Giannelli
Publikováno v:
Biology, Vol 13, Iss 4, p 256 (2024)
Klebsiella pneumoniae (Kp) is a Gram-negative bacterium, and a leading cause of neonatal sepsis in low- and middle-income countries, often associated with anti-microbial resistance. Two types of polysaccharides are expressed on the Kp cell surface an
Externí odkaz:
https://doaj.org/article/adc10b896e684480a1b47e5587ca9a5f
Autor:
Gianmarco Gasperini, Maria Michelina Raso, Fabiola Schiavo, Maria Grazia Aruta, Neil Ravenscroft, Barbara Bellich, Paola Cescutti, Francesca Necchi, Rino Rappuoli, Francesca Micoli
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Generalized modules for membrane antigens (GMMA) are exosomes released from engineered Gram-negative bacteria and represent an attractive vaccine platform for the delivery of the O-Antigen (OAg), recognized as the key target for protective i
Externí odkaz:
https://doaj.org/article/4ee5f5a7e3d24503b789d72b843465ba
Autor:
Sandra Van Puyvelde, Gianmarco Gasperini, Michael Biggel, Marie-France Phoba, Maria Michelina Raso, Tessa de Block, Leen N. Vanheer, Stijn Deborggraeve, Olivier Vandenberg, Nicholas Thomson, Neil Ravenscroft, Calman A. Maclennan, Barbara Bellich, Paola Cescutti, Gordon Dougan, Jan Jacobs, Octavie Lunguya, Francesca Micoli
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Salmonella enterica serovar Typhimurium causes a devastating burden of invasive disease in sub-Saharan Africa with high levels of antimicrobial resistance. No licensed vaccine is available, but O-antigen-based candidates are in development,
Externí odkaz:
https://doaj.org/article/f07235cd09194128ad4447c78c129175
Autor:
Francesca Mancini, Gianmarco Gasperini, Omar Rossi, Maria Grazia Aruta, Maria Michelina Raso, Renzo Alfini, Massimiliano Biagini, Francesca Necchi, Francesca Micoli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract GMMA are exosomes released from engineered Gram-negative bacteria resembling the composition of outer membranes. We applied the GMMA technology for the development of an O-Antigen (OAg) based vaccine against Shigella sonnei, the most epidemi
Externí odkaz:
https://doaj.org/article/0a9858c796534422bc600eb1b85c85dd
Toward a Shigella Vaccine: Opportunities and Challenges to Fight an Antimicrobial-Resistant Pathogen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4649 (2023)
Shigellosis causes more than 200,000 deaths worldwide and most of this burden falls on Low- and Middle-Income Countries (LMICs), with a particular incidence in children under 5 years of age. In the last decades, Shigella has become even more worrisom
Externí odkaz:
https://doaj.org/article/957022dfdbfa4f98b8c7da9e8ac2423d
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12160 (2021)
Shigella is a leading diarrheal cause of morbidity and mortality worldwide, especially in low- and middle-income countries and in children under five years of age. Increasing levels of antimicrobial resistance make vaccine development an even higher
Externí odkaz:
https://doaj.org/article/0f77f58ebcc1413f9b61e7f2f82376bc