Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Maria Marta Facchinetti"'
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 1, Pp 197-204 (1998)
In rat skeletal muscle, calcitriol, the hormonal form of vitamin D3, rapidly stimulates the biphasic formation of diacylglycerol (DAG), the second phase being independent of phosphoinositide hydrolysis driven by phospholipase C. In this work we showe
Externí odkaz:
https://doaj.org/article/8830437deb024effa7bcfbc75e5a97d3
Autor:
Maria Marta Facchinetti
Publikováno v:
Antioxidants & Redox Signaling. 32:1239-1242
This Forum issue “Heme Oxygenase” (HO) includes original research articles and reviews that are aimed at understanding the role of HO-1 in several pathophysiological conditions, specially addressing those involving inflammation and oxidative dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82ca86aa0a074fb88178bcfd0c15e23
https://doi.org/10.1089/ars.2020.8065
https://doi.org/10.1089/ars.2020.8065
Autor:
Maria Marta Facchinetti, Eliana Noelia Alonso, Alejandro Carlos Curino, Marilina Mascaró, Ezequiel Lacunza, Exequiel Alonso
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 87, p 87 (2021)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Antioxidants, Vol 10, Iss 87, p 87 (2021)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Heme Oxygenase-1 (HO-1) is a type II detoxifying enzyme that catalyzes the rate-limiting step in heme degradation leading to the formation of equimolar quantities of carbon monoxide (CO), free iron and biliverdin. HO-1 was originally shown to localiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d20e6604315816363baea8f86d09a0
http://europepmc.org/articles/PMC7826503
http://europepmc.org/articles/PMC7826503
Vitamin D analogues exhibit antineoplastic activity in breast cancer patient-derived xenograft cells
Autor:
Giuliana Paolillo, Mercedes Nadal Serrano, Marilina Mascaró, Alejandro Carlos Curino, Cristian Vitale, Yagamare Fall, Enrique Javier Arenas Lahuerta, Alex Martinez-Sabadell Aliguer, Hugo Santalla, Maria Marta Facchinetti, Cristina Bernadó Morales, Joaquín Arribas, María Julia Ferronato
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Despite advances in breast cancer (BC) treatment, its mortality remains high due to intrinsic or acquired resistance to therapy. Several ongoing efforts are being made to develop novel drugs to treat this pathology with the aim to overcome resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a88ffc6564418f180f19d19b9b0716
https://www.sciencedirect.com/science/article/abs/pii/S0960076020302600
https://www.sciencedirect.com/science/article/abs/pii/S0960076020302600
Autor:
Julian Naipauer, Martín Carlos Abba, Edith C. Kordon, Norberto Ariel Gandini, Maria Marta Facchinetti, Romina Canzoneri, A. Rodriguez Peña, Micaela Nadia Stedile, Ezequiel Lacunza, Alejandro Carlos Curino, Omar A. Coso
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
It has been established that ZFP36 (also known as Tristetraprolin or TTP) promotes mRNA degradation of proteins involved in inflammation, proliferation and tumor invasiveness. In mammary epithelial cells ZFP36 expression is induced by STAT5 activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc013df10613f3f2f0f3135b235db8c5
https://pubmed.ncbi.nlm.nih.gov/32248342/
https://pubmed.ncbi.nlm.nih.gov/32248342/
Autor:
Alejandro Carlos Curino, Yagamare Fall, Mario Alfredo Quevedo, Cristian Vitale, Sergio R. Ribone, Maria Marta Facchinetti, María Julia Ferronato
The vitamin D receptor (VDR) constitutes a promising therapeutic target for the treatment of cancer. Unfortunately, its natural agonist calcitriol does not have clinical utility due to its potential to induce hypercalcemic effects at the concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dee002db523e09d771d4bde51e8a7de
https://linkinghub.elsevier.com/retrieve/pii/S0960076019307241
https://linkinghub.elsevier.com/retrieve/pii/S0960076019307241
Autor:
María Julia Ferronato, Mario Alfredo Quevedo, Alejandro Carlos Curino, Eliana Noelia Alonso, Santiago Armando Stabile, Evangelina Mascaró, Gabriel Radivoy, Maria Marta Facchinetti, Silvina Mariela Grioli, Cristian Vitale
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 17(3)
Background:1α,25-dihydroxy vitamin D3 (calcitriol) shows potent growth-inhibitory properties on different cancer cell lines, but its hypercalcemic effects have severely hampered its therapeutic application. Therefore, it is important to develop synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505b0d91a6f4320d41be472d9dbc9252
https://pubmed.ncbi.nlm.nih.gov/32819231
https://pubmed.ncbi.nlm.nih.gov/32819231
Autor:
Georgina Pamela Coló, Marilina Mascaró, Maria Marta Facchinetti, Martín Carlos Abba, Norberto Ariel Gandini, María Eugenia Fermento, María Julia Ferronato, Eliana Noelia Alonso, Julián Arévalo, Myriam Nuñez, Pamela Pichel, Alejandro Carlos Curino, Josefina Alejandra Guevara
Publikováno v:
Antioxidants & Redox Signaling. 30
Aims:Heme oxygenase-1 (HO-1) is an enzyme involved in cellular responses to oxidative stress and has alsobeen shown to regulate processes related to cancer progression. In this regard, HO-1 has been shown to displaya dual effect with either antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d79e1ed0f653b56423852754b5f6278
https://doi.org/10.1089/ars.2018.7554
https://doi.org/10.1089/ars.2018.7554
Autor:
Yagamare Fall, Diego Javier Obiol, Generosa Gómez, Eliana Noelia Alonso, Maria Marta Facchinetti, Mario Alfredo Quevedo, María Julia Ferronato, Andrea Martínez, Silvina Mariela Grioli, Alejandro Carlos Curino
The active form of vitamin D3, calcitriol, is a potent antiproliferative compound. However, when effective antitumor doses of calcitriol are used, hypercalcemic effects are observed, thus blocking its therapeutic application. To overcome this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0125fb5e0309b464d55547d1a0972b62
Wiley Online Library
Wiley Online Library
Antitumoral and antimetastatic activity of Maitake D-Fraction in triple-negative breast cancer cells
Autor:
María Julia Ferronato, Alejandro López Romero, Josefina Alejandra Guevara, Norberto Ariel Gandini, Maria Marta Facchinetti, María Eugenia Fermento, Alejandro Carlos Curino, Eliana Noelia Alonso
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
Triple-negative breast cancer (TNBC) is associated with poor prognosis, high local recurrence rate and high rate of metastasis compared with other breast cancer subtypes. In addition, TNBC lacks a targeted therapy. This scenario highlights the need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdece524e05e26008b0e310f5470e6ad
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=25174&path[]=78890
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=25174&path[]=78890