Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maria Martínez-Iniesta"'
Autor:
Cristina Oliveira-Mateos, Anaís Sánchez-Castillo, Marta Soler, Aida Obiols-Guardia, David Piñeyro, Raquel Boque-Sastre, Maria E. Calleja-Cervantes, Manuel Castro de Moura, Anna Martínez-Cardús, Teresa Rubio, Joffrey Pelletier, Maria Martínez-Iniesta, David Herrero-Martín, Oscar M. Tirado, Antonio Gentilella, Alberto Villanueva, Manel Esteller, Lourdes Farré, Sonia Guil
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
RPSAP52 is an antisense-transcribed pseudogene of HMGA2 that positively regulates HMGA2 expression. Here, the authors show that reexpression of RPSAP52 promotes tumorigenicity by facilitating IGF2BP2 binding to its mRNA targets and consequently regul
Externí odkaz:
https://doaj.org/article/997060ff259e4adbb35655aa6d12600d
Autor:
Mireia Berdiel-Acer, Monika E. Bohem, Adriana López-Doriga, August Vidal, Ramon Salazar, Maria Martínez-Iniesta, Cristina Santos, Xavier Sanjuan, Alberto Villanueva, David G. Molleví
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 10, Pp 931-946 (2011)
Carcinoma-associated fibroblasts (CAFs) are important contributors of microenvironment in determining the tumor’s fate. This study aimed to compare the influence of liver microenvironment and primary tumor microenvironment on the behavior of colore
Externí odkaz:
https://doaj.org/article/5c9b3087d4474f888cb5a2fb45e64644
Autor:
Conxi Lázaro, Marc Ferrer, Alberto Villanueva, Eduard Serra, Miguel Angel Pujana, Jordi Serra-Musach, Jaishri O. Blakely, Karlyne M. Reilly, Lourdes Salazar-Huayna, Cleofe Romagosa, Margaret R. Wallace, Craig J. Thomas, Rajarshi Guha, Sara Ortega-Bertran, Maria Martínez-Iniesta, Xiaohu Zhang, Edgar Creus-Bachiller, Juana Fernández-Rodríguez
Supplementary Figure from A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4847b871cf8cf7c4068addd9e778cdae
https://doi.org/10.1158/1535-7163.22521984
https://doi.org/10.1158/1535-7163.22521984
Autor:
Conxi Lázaro, Marc Ferrer, Alberto Villanueva, Eduard Serra, Miguel Angel Pujana, Jordi Serra-Musach, Jaishri O. Blakely, Karlyne M. Reilly, Lourdes Salazar-Huayna, Cleofe Romagosa, Margaret R. Wallace, Craig J. Thomas, Rajarshi Guha, Sara Ortega-Bertran, Maria Martínez-Iniesta, Xiaohu Zhang, Edgar Creus-Bachiller, Juana Fernández-Rodríguez
Malignant peripheral nerve sheath tumors (MPNST) are soft-tissue sarcomas that are the leading cause of mortality in patients with Neurofibromatosis type 1 (NF1). Single chemotherapeutic agents have shown response rates ranging from 18% to 44% in cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227e325d82bacf02921d93b66758cec7
https://doi.org/10.1158/1535-7163.c.6543243
https://doi.org/10.1158/1535-7163.c.6543243
Autor:
Conxi Lázaro, Marc Ferrer, Alberto Villanueva, Eduard Serra, Miguel Angel Pujana, Jordi Serra-Musach, Jaishri O. Blakely, Karlyne M. Reilly, Lourdes Salazar-Huayna, Cleofe Romagosa, Margaret R. Wallace, Craig J. Thomas, Rajarshi Guha, Sara Ortega-Bertran, Maria Martínez-Iniesta, Xiaohu Zhang, Edgar Creus-Bachiller, Juana Fernández-Rodríguez
Supplementary Table from A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc852bdd08298b841c8a6751ecfee4f
https://doi.org/10.1158/1535-7163.22521981
https://doi.org/10.1158/1535-7163.22521981
Autor:
Marie-Julie Nokin, Alessia Mira, Enrico Patrucco, Biagio Ricciuti, Sophie Cousin, Isabelle Soubeyran, Sonia San José, Serena Peirone, Livia Caizzi, Sandra Vietti Michelina, Aurelien Bourdon, Xinan Wang, Daniel Alvarez-Villanueva, María Martínez-Iniesta, August Vidal, Telmo Rodrigues, Carmen García-Macías, Mark M. Awad, Ernest Nadal, Alberto Villanueva, Antoine Italiano, Matteo Cereda, David Santamaría, Chiara Ambrogio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Selective KRASG12C inhibitors have been developed to covalently lock the oncogene in the inactive GDP-bound state. Two of these molecules, sotorasib and adagrasib, are approved for the treatment of adult patients with KRASG12C-mutated previo
Externí odkaz:
https://doaj.org/article/720b0c9c9a024f38961f97cf298e776d
Autor:
Juana Fernández-Rodríguez, Edgar Creus-Bachiller, Xiaohu Zhang, Maria Martínez-Iniesta, Sara Ortega-Bertran, Rajarshi Guha, Craig J. Thomas, Margaret R. Wallace, Cleofe Romagosa, Lourdes Salazar-Huayna, Karlyne M. Reilly, Jaishri O. Blakely, Jordi Serra-Musach, Miguel Angel Pujana, Eduard Serra, Alberto Villanueva, Marc Ferrer, Conxi Lázaro
Publikováno v:
Mol Cancer Ther
Molecular Cancer Therapeutics
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Molecular Cancer Therapeutics
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Malignant peripheral nerve sheath tumors (MPNST) are soft-tissue sarcomas that are the leading cause of mortality in patients with Neurofibromatosis type 1 (NF1). Single chemotherapeutic agents have shown response rates ranging from 18% to 44% in cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a0bf5d46410009b07abaca8c6936a3
https://europepmc.org/articles/PMC9256801/
https://europepmc.org/articles/PMC9256801/
Autor:
Laura Solé, Teresa Lobo-Jarne, Daniel Álvarez-Villanueva, Josune Alonso-Marañón, Yolanda Guillén, Marta Guix, Irene Sangrador, Catalina Rozalén, Anna Vert, Antonio Barbachano, Joan Lop, Marta Salido, Beatriz Bellosillo, Raquel García-Romero, Marta Garrido, Jessica González, María Martínez-Iniesta, Erika López-Arribillaga, Ramón Salazar, Clara Montagut, Ferrán Torres, Mar Iglesias, Toni Celià-Terrassa, Alberto Muñoz, Alberto Villanueva, Anna Bigas, Lluís Espinosa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The failure of chemotherapy in colorectal cancer is currently unclear. Here, the authors show that upon sub-lethal dose of chemotherapy wild-type p53 colorectal cancers acquire a quiescence-like phenotype and a YAP-dependent fetal-like intestinal ste
Externí odkaz:
https://doaj.org/article/a95e4335e7804b569fac9baa390c372b
Autor:
Laura Devis‐Jauregui, August Vidal, Laura Plata‐Peña, Maria Santacana, Sandra García‐Mulero, Nuria Bonifaci, Eulàlia Noguera‐Delgado, Nuria Ruiz, Marta Gil, Eduard Dorca, Francisco J. Llobet, Laura Coll‐Iglesias, Katja Gassner, Maria Martinez‐Iniesta, Ruth Rodriguez‐Barrueco, Marc Barahona, Lola Marti, Francesc Viñals, Jordi Ponce, Rebeca Sanz‐Pamplona, Josep M. Piulats, Ana Vivancos, Xavier Matias‐Guiu, Alberto Villanueva, David Llobet‐Navas
Publikováno v:
Advanced Science, Vol 10, Iss 1, Pp n/a-n/a (2023)
Abstract Clinical management of endometrial cancer (EC) is handicapped by the limited availability of second line treatments and bona fide molecular biomarkers to predict recurrence. These limitations have hampered the treatment of these patients, wh
Externí odkaz:
https://doaj.org/article/88510e34e7fe4b8697754d4822ed3e67
Autor:
Lourdes Farre, Gabriela Sanz, Neus Ruiz-Xivillé, Manuel Castro de Moura, Juan Francisco Martin-Tejera, Samuel Gonçalves-Ribeiro, Maria Martinez-Iniesta, Monica Calaf, Jose Luis Mosquera, José Ignacio Martín-Subero, Isabel Granada, Manel Esteller, Eva Domingo-Domenech, Fina Climent, Alberto Villanueva, Anna Sureda
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 7 (2021)
Extramedullary multiple myeloma (EMM) has an overall survival of 6 months and occurs in 20% of multiple myeloma (MM) patients. Genetic and epigenetic mechanisms involved in EMM and the therapeutic role of new agents for MM are not well established. B
Externí odkaz:
https://doaj.org/article/dcb75710098f46c6a214863a7b8ea36e