Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Maria Marlow"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
During the foreign body response (FBR), macrophages fuse to form foreign body giant cells (FBGCs). Modulation of FBGC formation can prevent biomaterial degradation and loss of therapeutic efficacy. However, the microenvironmental cues that dictate FB
Externí odkaz:
https://doaj.org/article/b0cdf0ce386e4d35a6a430a272c9a3c1
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 571 (2022)
Historically, pre-clinical neuro-oncological drug delivery studies have exhaustively relied upon overall animal survival as an exclusive measure of efficacy. However, with no adopted methodology to both image and quantitate brain parenchyma penetrati
Externí odkaz:
https://doaj.org/article/f34ed7de76f3431c8b60fe5cb6cfd5a2
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 19, Iss 4 (2019)
The assessment of drug permeation into/across the skin is traditionally accomplished using Franz diffusion cells with subsequent analysis by conventional chromatographic methods such as HPLC and more recently using advanced imaging techniques. In thi
Externí odkaz:
https://doaj.org/article/3d52e0a412f444d4a27942b2c044a355
Autor:
Songtao Xue, Zhiwei Li, Xiaotong Ze, Xiuyuan Wu, Chen He, Wen Shuai, Maria Marlow, Jian Chen, David Scurr, Zheying Zhu, Jinyi Xu, Shengtao Xu
Publikováno v:
Journal of Medicinal Chemistry. 66:5099-5117
Autor:
Paula Muresan, Phoebe McCrorie, Fiona Smith, Catherine Vasey, Vincenzo Taresco, David J. Scurr, Stefanie Kern, Stuart Smith, Pavel Gershkovich, Ruman Rahman, Maria Marlow
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
Systemic drug delivery to the central nervous system (CNS) has been historically impeded by the presence of the blood brain barrier rendering many therapies inefficacious to any cancer cells residing within the brain. Therefore, local drug delivery s
Autor:
Paula Muresan, Stephen Woodhams, Fiona Smith, Vincenzo Taresco, Jaymin Shah, Mei Wong, Victoria Chapman, Stuart Smith, Gareth Hathway, Ruman Rahman, Pavel Gershkovich, Maria Marlow
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 49:102664
Autor:
Stuart Smith, Maria Marlow, Phoebe McCrorie, Catherine E. Vasey, Ruman Rahman, Cameron Alexander
Publikováno v:
Journal of Controlled Release. 328:917-931
© 2020 We review the challenges of next-generation therapeutics for both systemic and localised delivery to brain tumours and discuss how recent engineering advances may be used to enhance brain penetration of systemic delivery therapies. The unmet
Autor:
Fiona Smith, Akmal H. Sabri, Matthew Heppel, Ines Fonseca, Faz Chowdhury, Karmen Cheung, Stephen Willmor, Frankie Rawson, Maria Marlow
Publikováno v:
International journal of pharmaceutics. 628
Microneedles have the clinical advantage of being able to deliver complex drugs across the skin in a convenient and comfortable manner yet haven't successfully transitioned to medical practice. Diabetes mellitus is a complicated disease, which is com
Autor:
Maria Marlow, Long Jiang, Sunil Rajput, Jonathan Rawle, Dave J. Adams, Marina Lledos, Chunyu Jin, Emanuele Russo, Bin Yang, Giuseppe Ciccone, Massimo Vassalli, Mischa Zelzer, Thomas Arnold, Maria Galini Faidra Angelereou, Riaz Akhtar
Publikováno v:
Chemical Science
Controlling supramolecular self-assembly across multiple length scales to prepare gels with localised properties is challenging. Most strategies concentrate on fabricating gels with heterogeneous components, where localised properties are generated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6699dd3d4983d73a0f551905030c8af2
https://nottingham-repository.worktribe.com/file/7354675/1/Yang-cs-2021
https://nottingham-repository.worktribe.com/file/7354675/1/Yang-cs-2021
Autor:
Cara Moloney, Phoebe McCrorie, Chiara Bastianchich, Bernard Ucakar, Cameron Alexander, Maria Marlow, Véronique Préat, Ruman Rahman
Publikováno v:
Neuro-Oncology. 24:vii94-vii94
Local intracranial drug delivery for high-grade glioma has been developed over the last two decades with chemotherapeutic agents administered immediately adjuvant to neurosurgery to overcome poor blood brain barrier permeability. In addition to this,