Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Maria Marjorette O. Peña"'
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2676 (2018)
Cancer is initiated by mutations in critical regulatory genes; however, its progression to malignancy is aided by non-neoplastic cells and molecules that create a permissive environment known as the tumor stroma or microenvironment (TME). Interleukin
Externí odkaz:
https://doaj.org/article/cbf47f0779094c7da6332f8516073de8
Autor:
William J.M. Hrushesky, Maria Marjorette O. Peña, Franklin G. Berger, Kevin Carnevale, Ziad Al-Assaad, Stacy E. Ayers, Christine Ansell, Eun-Young Oh, Andrew Taber, Xiaoming Yang, Patricia A. Wood
Colorectal cancer risk is increased in shift workers with presumed circadian disruption. Intestinal epithelial cell proliferation is gated throughout each day by the circadian clock. Period 2 (Per2) is a key circadian clock gene. Per2 mutant (Per2m/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1371928d12d3274c4b8d55be4e07f94c
https://doi.org/10.1158/1541-7786.c.6541435.v1
https://doi.org/10.1158/1541-7786.c.6541435.v1
Autor:
William J.M. Hrushesky, Maria Marjorette O. Peña, Franklin G. Berger, Kevin Carnevale, Ziad Al-Assaad, Stacy E. Ayers, Christine Ansell, Eun-Young Oh, Andrew Taber, Xiaoming Yang, Patricia A. Wood
Supplementary Data from Period 2 Mutation Accelerates ApcMin/+ Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f1531b42e9a1fc25a6ff85cbc6126d
https://doi.org/10.1158/1541-7786.22516660
https://doi.org/10.1158/1541-7786.22516660
Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota
Autor:
Brandon N. VanderVeen, James A. Carson, Ioulia Chatzistamou, E. A. Murphy, Maria Marjorette O. Peña, Meredith S. Carson, Jason L. Kubinak, Jackie E. Bader, Michael D. Walla, Alexander T Sougiannis, Reilly T. Enos, Mitzi Nagarkatti, Kandy T. Velázquez
Publikováno v:
Brain Behav Immun
Emerging evidence suggests that gut microbiota may influence the response to chemotherapy. We sought to characterize the effects of 5 fluorouracil (5FU) chemotherapy on colon inflammation and functional measures in colorectal cancer (CRC) and to furt
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2676 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cancer is initiated by mutations in critical regulatory genes; however, its progression to malignancy is aided by non-neoplastic cells and molecules that create a permissive environment known as the tumor stroma or microenvironment (TME). Interleukin
Autor:
Yu Zhang, Celestia Davis, Sapana N. Shah, Diego Altomare, Daniel Hughes, Maria Marjorette O. Peña, James C. Ryan
Publikováno v:
Molecular Carcinogenesis. 56:272-287
Liver metastasis is the major cause of death from colorectal cancer (CRC). Understanding its mechanisms is necessary for timely diagnosis and development of effective therapies. Interleukin-33 (IL-33) is an IL-1 cytokine family member that uniquely f
Autor:
Amit Sheth, E. Angela Murphy, Franklin G. Berger, Hexin Chen, Maria Marjorette O. Peña, Lorne J. Hofseth, Anindya Chanda, Phillip Buckhaults, James R. Hebert, Mathew Sajish, Bryan L. Love
Publikováno v:
Nature Reviews Gastroenterology & Hepatology. 17:517-517
Autor:
Igor B. Roninson, Eugenia V. Broude, Alexander A. Chumanevich, Daniel Hughes, Mengqian Chen, Karthikeyan Mythreye, Serena Altilia, Chang-uk Lim, Vimala Kaza, Maria Marjorette O. Peña, Jiaxin Liang, Hippokratis Kiaris
Publikováno v:
Cancer research. 78(23)
Unresectable hepatic metastases of colon cancer respond poorly to existing therapies and are a major cause of colon cancer lethality. In this study, we evaluated the therapeutic viability of targeting the mediator kinase CDK8, an early clinical stage
Autor:
Celestia Davis, Maria Marjorette O. Peña, Sizolwenkosi Mlotshwa, John L. MacArthur, Lorne J. Hofseth, Vicki B. Vance, Matthew W. Endres, Gail J. Pruss
Publikováno v:
Cell Research
The homeoprotein Six1 is overexpressed in many human cancers and is associated with increased tumor progression and metastasis. Recent studies have shown that Six1 is associated with poorer overall survival in advanced-stage colorectal cancer (CRC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e39eb35619305d0cf4ac892ae11d32
https://europepmc.org/articles/PMC5862328/
https://europepmc.org/articles/PMC5862328/