Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Maria Marcela Barrio"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cancer vaccines are gaining ground as immunotherapy options. We have previously demonstrated in cutaneous melanoma (CM) patients that adjuvant treatment with VACCIMEL, a mixture of four irradiated CM cell lines co-adjuvanted with BCG and GM-CSF, incr
Externí odkaz:
https://doaj.org/article/7afb959f2f47486da5f357218409181c
Autor:
Abdullah Al Emran, Florencia Paula Madorsky Rowdo, Stuart John Gallagher, Peter Hersey, Maria Marcela Barrio, Erika von Euw, José Mordoh, Antonela Barón
Publikováno v:
International Journal of Oncology
It is estimated that ~50% of patients with melanoma harbour B‑Raf (BRAF)V600 driver mutations, with the most common of these being BRAFV600E, which leads to the activation of mitogen‑activated protein kinase proliferative and survival pathways. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa7d2770ffeb7466fc802c5ff35ede1
https://pubmed.ncbi.nlm.nih.gov/32236593
https://pubmed.ncbi.nlm.nih.gov/32236593
Autor:
Ibel Carri, Erika Schwab, Enrique Podaza, Heli M. Garcia Alvarez, José Mordoh, Morten Nielsen, María Marcela Barrio
Publikováno v:
Exploration of Immunology, Vol 3, Iss 2, Pp 82-103 (2023)
In the last years, multiple efforts have been made to accurately predict neoantigens derived from somatic mutations in cancer patients, either to develop personalized therapeutic vaccines or to study immune responses after cancer immunotherapy. In th
Externí odkaz:
https://doaj.org/article/20a4ab5fe42740d892c2977300cc671e
Autor:
José Mordoh, Gabriela Andrea Pizzurro, Leonardo Sganga, Osvaldo L. Podhajcer, Ivana Jaqueline Tapia, Maria Marcela Barrio
Publikováno v:
Cancer Immunology, Immunotherapy. 64:1393-1406
Dendritic cells (DCs) are professional APCs used for the development of cancer vaccines because of their ability to activate adaptive immune responses. Previously, we designed the DC/Apo-Nec vaccine using human DCs loaded with dying melanoma cells th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e98a3cd6e036932bb478bb241ebfee
https://doi.org/10.1007/s00262-015-1743-z
https://doi.org/10.1007/s00262-015-1743-z
Autor:
Maria Paula Roberti, Estefanía Paula Juliá, Estrella Mariel Levy, Ariel Podhorzer, Maria Marcela Barrio, Leonardo Fainboim, Federico Coló, Merecedes Maino, Alicia I. Bravo, Jose Loza, Carlos Martin Loza, Yamila S. Rocca, Verónica Fabiano, José Mordoh, Mora Amat
Publikováno v:
European Journal of Immunology. 45:1560-1569
Clinical studies suggest that triple negative breast cancer (TNBC) patients with epidermal growth factor receptor (EGFR)-expressing tumors could benefit from therapy with Cetuximab, which targets EGFR. NK cells are the primary effectors of antibody (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6536338b364256ce1bba61f190748a55
https://doi.org/10.1002/eji.201445353
https://doi.org/10.1002/eji.201445353
Autor:
Ana Mordoh, Juan Carlos Triviño Pardo, Ibel Carri, María Marcela Barrio, José Mordoh, Mariana Aris
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Background Cutaneous melanoma is the skin cancer with the highest mutational burden and metastatic rate. Early genetic alterations and biomarkers of distant progression are a point of interest. In addition to germline-susceptibility loci, al
Externí odkaz:
https://doaj.org/article/d069418855944f2f9f450f9164198f99
Autor:
Alicia Inés Bravo, Mariana Aris, Marylou Panouillot, Martina Porto, Marie-Caroline Dieu-Nosjean, Jean-Luc Teillaud, María Marcela Barrio, José Mordoh
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTissue biomarkers that aid in identifying cutaneous melanoma (CM) patients who will benefit from adjuvant immunotherapy are of crucial interest. Metastatic tumor-draining lymph nodes (mTDLN) are the first encounter site between the metast
Externí odkaz:
https://doaj.org/article/31317a4b55ec4d338dd8504276aa036a
Autor:
Maria Paula Roberti, Michele Bianchini, María Betina Pampena, Alicia I. Bravo, Federico Coló, Mora Amat, José Mordoh, Yamila S. Rocca, Reinaldo Chacón, Juan Martín Arriaga, Verónica Fabiano, Jose Loza, Carlos Martin Loza, Estrella Mariel Levy, Maria Marcela Barrio, Enzo Domenichini
Publikováno v:
Breast Cancer Research and Treatment. 136:659-671
Triple-negative breast cancer (TNBC) patients do not benefit from target-specific treatments and is associated with a high relapse rate. Epidermal growth factor receptor is frequently expressed in TNBC and is a candidate for new therapies. In this wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6eeb2f71b0b3bc7d9bd1b5228d5bec1
https://doi.org/10.1007/s10549-012-2287-y
https://doi.org/10.1007/s10549-012-2287-y
Autor:
Alicia I. Bravo, Mariana Rodriguez Zubieta, José Mordoh, Myriam Alperovich, Mariana Aris, Juan Martín Arriaga, Maria Marcela Barrio, Marina Colombo, Michele Bianchini
Publikováno v:
Journal of Investigative Dermatology. 132:365-374
MART-1 and gp100 are prototypical melanoma antigen (Ag), but their clinical use as vaccines or as targets of cytotoxic lymphocytes achieved modest success. Possible explanations could be that as MART-1 and gp100 are melanocyte differentiation Ag, clo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f30814bc09da7196c672614d69d775
https://doi.org/10.1038/jid.2011.312
https://doi.org/10.1038/jid.2011.312
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
Clinical and Developmental Immunology
Clinical and Developmental Immunology
We will revisit the dual role of the immune system in controlling and enabling tumor progression, known ascancer immunoediting. We will go through the different phases of this phenomenon, exposing the most relevant evidences obtained from experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383577968885d3207fe09ba20f53119d
https://doi.org/10.1155/2012/192719
https://doi.org/10.1155/2012/192719