Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maria Malmlöf"'
Autor:
Jie Ji, Swapna Upadhyay, Xiaomiao Xiong, Maria Malmlöf, Thomas Sandström, Per Gerde, Lena Palmberg
Publikováno v:
Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-16 (2018)
Abstract Background Diesel exhaust particles (DEP) are a major component of outdoor air pollution. DEP mediated pulmonary effects are plausibly linked to inflammatory and oxidative stress response in which macrophages (MQ), epithelial cells and their
Externí odkaz:
https://doaj.org/article/1d02d3400e9b4c60a9f3ca11479ad8e0
Autor:
Francesca Cappellini, Sebastiano Di Bucchianico, Venkatanaidu Karri, Siiri Latvala, Maria Malmlöf, Maria Kippler, Karine Elihn, Jonas Hedberg, Inger Odnevall Wallinder, Per Gerde, Hanna L. Karlsson
Publikováno v:
Nanomaterials, Vol 10, Iss 4, p 618 (2020)
Relevant in vitro assays that can simulate exposure to nanoparticles (NPs) via inhalation are urgently needed. Presently, the most common method employed is to expose lung cells under submerged conditions, but the cellular responses to NPs under such
Externí odkaz:
https://doaj.org/article/24ed020eb87c4b6da77d8173f0444817
Autor:
Jie Ji, Anna Hedelin, Maria Malmlöf, Vadim Kessler, Gulaim Seisenbaeva, Per Gerde, Lena Palmberg
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170428 (2017)
Exposure to agents via inhalation is of great concerns both in workplace environment and in the daily contact with particles in the ambient air. Reliable human airway exposure systems will most likely replace animal experiment in future toxicity asse
Externí odkaz:
https://doaj.org/article/189ebd78ac10423a953b917c0b87e4f3
Autor:
M. Luísa Corvo, Beatriz Noriega-Fernandes, Mattias Nowenwik, Maria Malmlöf, Eunice Costa, Per Gerde
Publikováno v:
International journal of pharmaceutics. 607
The composition, morphology and dissolution profile of particles and micro-sized agglomerates delivered upon inhalation may have a significant impact on the product clinical effect. However, although several efforts are ongoing, a methodology that co
Autor:
Thomas Sandström, Maria Malmlöf, Per Gerde, Xiaomiao Xiong, Lena Palmberg, Swapna Upadhyay, Jie Ji
Publikováno v:
Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-16 (2018)
Particle and Fibre Toxicology
Particle and Fibre Toxicology
Background Diesel exhaust particles (DEP) are a major component of outdoor air pollution. DEP mediated pulmonary effects are plausibly linked to inflammatory and oxidative stress response in which macrophages (MQ), epithelial cells and their cell-cel
Autor:
Maria Malmlöf, Xenia Mihai, Lena Palmberg, Jitong Sun, Per Gerde, Koustav Ganguly, Jie Ji, Swapna Upadhyay
Publikováno v:
Nanotoxicology. 13(10)
Carbon nanoparticles (CNP) are generated by incomplete combustion of diesel engines. Several epidemiological studies associated higher susceptibility to particulate matter related adverse respiratory outcomes with preexisting conditions like chronic
Publikováno v:
Journal of Aerosol Science. 151:105698
Correlating data from in vitro dissolution testing of inhaled particulate pharmaceuticals or air pollutants with the dissolution and distribution to the blood circulation of the same aerosols following inhalation in vivo is a major challenge. Better
Autor:
Per Gerde, Venkatanaidu Karri, Karine Elihn, Francesca Cappellini, Maria Kippler, Inger Odnevall Wallinder, Maria Malmlöf, Jonas Hedberg, Sebastiano Di Bucchianico, Siiri Latvala, Hanna L. Karlsson
Publikováno v:
Nanomaterials 10:618 (2020)
Nanomaterials
Volume 10
Issue 4
Nanomaterials, Vol 10, Iss 618, p 618 (2020)
Nanomaterials
Volume 10
Issue 4
Nanomaterials, Vol 10, Iss 618, p 618 (2020)
Relevant in vitro assays that can simulate exposure to nanoparticles (NPs) via inhalation are urgently needed. Presently, the most common method employed is to expose lung cells under submerged conditions, but the cellular responses to NPs under such
Autor:
Hermann Mascher, Per Gerde, Ewa Selg, John Burns, Mattias Nowenwik, Kristof Meelich, Iwona Rådberg, Maria Malmlöf
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 139
The surface area of the air/liquid interface in the lungs is substantial, so deposited doses of aerosol medicines per interface surface area when administered via the inhalation route is always quite low. However, in most in vitro systems used for di
Autor:
Carl-Olof Sjöberg, Stefan Eirefelt, Maria Malmlöf, Lina Havsborn, Katarina Ekelund, Per Gerde, Pär Ewing
Publikováno v:
Assay and drug development technologies. 15(2)
The main purpose of this work was to develop an in vitro method for simulating the dissolution and absorption of inhaled dry powder drugs that also mimics systemic pharmacokinetic data. A second purpose was to evaluate this method. DissolvIt® was de