Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Maria Malicka-Błaszkiewicz"'
Autor:
Katarzyna Pietraszek, Stéphane Brézillon, Corinne Perreau, Maria Malicka-Błaszkiewicz, François-Xavier Maquart, Yanusz Wegrowski
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76232 (2013)
Lumican, a small leucine-rich proteoglycan of the extracellular matrix, presents potent anti-tumor properties. Previous works from our group showed that lumican inhibited melanoma cell migration and tumor growth in vitro and in vivo. Melanoma cells a
Externí odkaz:
https://doaj.org/article/ae5ab7fe00754366943b9d0064a1254b
β-Catenin Expression Regulates Cell Migration of Human Colonic Adenocarcinoma Cells Through Gelsolin
Publikováno v:
Anticancer Research. 36:5249-5256
Background/aim β-Catenin is one of the key players in colonic carcinogenesis. Being part of the E-cadherin complex, it regulates cell-cell adhesion and the migratory ability of cells. However, the role of nuclear β-catenin in the cell migration pro
Autor:
Christophe Ampe, Dorota Nowak, Maria Malicka-Błaszkiewicz, Antonina Joanna Mazur, Aleksandra Simiczyjew, Marleen Van Troys
Publikováno v:
Experimental Cell Research. 339:206-219
Invadopodia are actin-rich protrusions formed by mesenchymally migrating cancer cells. They are mainly composed of actin, actin-associated proteins, integrins and proteins of signaling machineries. These protrusions display focalized proteolytic acti
Autor:
Dorota Nowak, Antonina Joanna Mazur, Maria Malicka-Błaszkiewicz, Aleksandra Makowiecka, Wilma A. Hofmann, Marta Migocka-Patrzałek
Publikováno v:
Histochemistry and Cell Biology
Actin is a highly conserved protein that is expressed in all eukaryotic cells and has essential functions in the cytoplasm and the nucleus. Nuclear actin is involved in transcription by all three RNA polymerases, chromatin remodelling, RNA processing
Autor:
Dorota Nowak, Maria Malicka-Błaszkiewicz, Gabriela Morosan-Puopolo, Beate Brand-Saberi, Aleksandra Makowiecka, Antonina Joanna Mazur
Publikováno v:
Brain Structure & Function
Gelsolin is one of the most intensively studied actin-binding proteins. However, in the literature comprehensive studies of GSN expression during development have not been performed yet in all model organisms. In zebrafish, gelsolin is a dorsalizing
Autor:
Agata Radwanska, François-Xavier Maquart, Dorota Nowak, Maria Malicka-Błaszkiewicz, Monika Litwin, Yanusz Wegrowski, Dagmara Baczynska
Publikováno v:
Experimental Cell Research
Experimental Cell Research, Elsevier, 2012, 318 (18), pp.2312-2323
Experimental Cell Research, Elsevier, 2012, 318 (18), pp.2312-2323
Cell migration is a multistep process initiated by extracellular matrix components that leads to cytoskeletal changes and formation of different protrusive structures at the cell periphery. Lumican, a small extracellular matrix leucine-rich proteogly
Autor:
Dorota Nowak, Maria Malicka-Błaszkiewicz, Aleksandra Woźniakowska, Agnieszka Popow-Woźniak, Łukasz Kaczmarek
Publikováno v:
European Journal of Pharmacology. 667:66-73
Imatinib mesylate (STI571) is the first member of a new class of agents that act by inhibiting specific tyrosine kinases, rather than killing all rapidly dividing cells. This drug is usually used in the treatment of chronic myelogenous leukemia and g
Autor:
Maria Malicka-Błaszkiewicz, Yanusz Wegrowski, Hélène Bobichon, François-Xavier Maquart, Agata Radwanska, Andrzej Małkowski, Dominique Ploton, Cedric Zeltz, Corinne Perreau, Stéphane Brézillon
Publikováno v:
Cancer Letters
Cancer Letters, Elsevier, 2009, 283 (1), pp.92-100
Cancer Letters, Elsevier, 2009, 283 (1), pp.92-100
Lumican is a small leucine-rich proteoglycan (SLRP) of the extracellular matrix (ECM) with anti-tumor activity. We recently demonstrated that lumican inhibits the migration of melanoma cells and identified beta1 integrin as mediator of this effect [M
Publikováno v:
European Journal of Pharmacology. 613:24-33
Methotrexate is a widely used drug in treatments of various types of malignancies and in the therapy of rheumatoid arthritis. The goal of our study was to look at the effect of this dihydrofolate reductase inhibitor on the actin cytoskeleton, since a
Autor:
Maria Malicka-Błaszkiewicz, Lukasz Kaczmarek, Katarzyna Suchoszek-Lukaniuk, Wanda Peczyńska-Czoch, Anna Jaromin, Arkadiusz Kozubek
Publikováno v:
Drug Delivery. 15:49-56
The cytotoxic and antitumor activity of DIMIQ (5,11-dimethyl-5H-indolo[2,3-b]quinoline), synthetic analog of neocryptolepine, makes this compound a potential antitumor agent. An attempt to obtain liposomal form of DIMIQ.HCl was undertaken in the pres