Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Maria Maddalena Simile"'
Autor:
Shanshan Deng, Xinjun Lu, Xue Wang, Binyong Liang, Hongwei Xu, Doris Yang, Guofei Cui, Andrew Yonemura, Honor Paine, Yi Zhou, Yi Zhang, Maria Maddalena Simile, Francesco Urigo, Matthias Evert, Diego F. Calvisi, Benjamin L. Green, Xin Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-11 (2024)
Abstract TBX3 behaves as a tumor suppressor or oncoprotein across cancer. However, TBX3 function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary liver malignancy with few systemic treatment options. This study sought
Externí odkaz:
https://doaj.org/article/904e8d75b78a4941a72af5c5e04ec7b8
Autor:
Maria Maddalena Simile, Paola Bagella, Gianpaolo Vidili, Angela Spanu, Roberto Manetti, Maria Antonietta Seddaiu, Sergio Babudieri, Giordano Madeddu, Pier Andrea Serra, Matteo Altana, Panagiotis Paliogiannis
Publikováno v:
Medicina, Vol 55, Iss 2, p 42 (2019)
Cholangiocarcinoma (CCA) is a highly-aggressive malignancy arising from the biliary tree, characterized by a steady increase in incidence globally and a high mortality rate. Most CCAs are diagnosed in the advanced and metastatic phases of the disease
Externí odkaz:
https://doaj.org/article/a834510c0d2248399865e98a8605f021
Autor:
Claudio F. Feo, Antonio Cigliano, Roberto Manetti, Panagiotis Paliogiannis, Rosa Maria Pascale, Lucia Daino, Maria Maddalena Simile, Diego F. Calvisi, Francesco Feo
Publikováno v:
Translational Oncology
Translational Oncology, Vol 15, Iss 1, Pp 101239-(2022)
Translational Oncology, Vol 15, Iss 1, Pp 101239-(2022)
Highlights • GNMT gene expression contributes to determine hepatocellular carcinoma (HCC) prognosis. • GNMT expression is genetically determined. • Nuclear GNMT binds to CYP1A1, PREX2, PARP1, and NFKB gene promoters and strongly inhibits their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df5592fa217de8c130d01f705143af7
http://europepmc.org/articles/PMC8517931
http://europepmc.org/articles/PMC8517931
Publikováno v:
Hepatoma Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63bdea7b98fa2afd9ac83576cd0f9ff8
https://doi.org/10.20517/2394-5079.2020.162
https://doi.org/10.20517/2394-5079.2020.162
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2819, p 2819 (2020)
Cancers, Vol 12, Iss 2819, p 2819 (2020)
Simple Summary The deregulation of the oxidative metabolism in cancer cells, characterized by an increased ratio between glycolysis and oxygen consumption (Warburgv effect) largely depends on metabolic and molecular variations including modifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f353c5e8632140d12c90633ac6e8c5f2
https://pubmed.ncbi.nlm.nih.gov/33008042
https://pubmed.ncbi.nlm.nih.gov/33008042
Autor:
Maria G. Pilo, Xin Chen, Rosa Maria Pascale, Maria Antonietta Seddaiu, Diego F. Calvisi, Alberto Porcu, Giuseppe Palmieri, Maria Cristina Sini, Gianpaolo Vidili, Frank Dombrowski, Gavinella Latte, Giovanni Mario Pes, Silvia Ribback, Marta Szydlowska, Li Che, Antonio Cossu, Antonio Cigliano, Lei Li, Panagiotis Paliogiannis, Maria Maddalena Simile
Publikováno v:
Oncotarget
Oncotarget 8 (2017): 90638–90650. doi:10.18632/oncotarget.21469
info:cnr-pdr/source/autori:Cigliano A.; Pilo M.G.; Li L.; Latte G.; Szydlowska M.; Simile M.M.; Paliogiannis P.; Che L.; Pes G.M.; Palmieri G.; Sini M.C.; Cossu A.; Porcu A.; Vidili G.; Seddaiu M.A.; Pascale R.M.; Ribback S.; Dombrowski F.; Chen X.; Calvisi D.F./titolo:Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis/doi:10.18632%2Foncotarget.21469/rivista:Oncotarget/anno:2017/pagina_da:90638/pagina_a:90650/intervallo_pagine:90638–90650/volume:8
Oncotarget, vol 8, iss 53
Oncotarget 8 (2017): 90638–90650. doi:10.18632/oncotarget.21469
info:cnr-pdr/source/autori:Cigliano A.; Pilo M.G.; Li L.; Latte G.; Szydlowska M.; Simile M.M.; Paliogiannis P.; Che L.; Pes G.M.; Palmieri G.; Sini M.C.; Cossu A.; Porcu A.; Vidili G.; Seddaiu M.A.; Pascale R.M.; Ribback S.; Dombrowski F.; Chen X.; Calvisi D.F./titolo:Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis/doi:10.18632%2Foncotarget.21469/rivista:Oncotarget/anno:2017/pagina_da:90638/pagina_a:90650/intervallo_pagine:90638–90650/volume:8
Oncotarget, vol 8, iss 53
// Antonio Cigliano 1,* , Maria G. Pilo 2,* , Lei Li 3,* , Gavinella Latte 2 , Marta Szydlowska 1 , Maria M. Simile 2 , Panagiotis Paliogiannis 2 , Li Che 4 , Giovanni M. Pes 2 , Giuseppe Palmieri 5 , Maria C. Sini 5 , Antonio Cossu 6 , Alberto Porcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f1c4eb15dd9ae1f64ae4ff00201ca8
http://europepmc.org/articles/PMC5710874
http://europepmc.org/articles/PMC5710874
Autor:
Xin Chen, Maria G. Pilo, Li Che, Antonio Cigliano, Diego F. Calvisi, Maria Maddalena Simile, Matthias Evert, Silvia Ribback, Frank Dombrowski, Gavinella Latte
Publikováno v:
Cell cycle (Georgetown, Tex.), vol 16, iss 6
Hepatocellular carcinoma (HCC), the most frequent primary tumor of the liver, is an aggressive cancer type with limited treatment options. Cumulating evidence underlines a crucial role of aberrant lipid biosynthesis (a process known as de novo lipoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d63046a5be256d7ec4f10fc1362d30d
https://doi.org/10.1080/15384101.2017.1282586
https://doi.org/10.1080/15384101.2017.1282586
Publikováno v:
Medicina, Vol 55, Iss 6, p 296 (2019)
Medicina
Medicina
Several researchers have analyzed the alterations of the methionine cycle associated with liver disease to clarify the pathogenesis of human hepatocellular carcinoma (HCC) and improve the preventive and the therapeutic approaches to this tumor. Diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570a1e574da52ab72c394bad0029c891
https://www.mdpi.com/1010-660X/55/6/296
https://www.mdpi.com/1010-660X/55/6/296
Post-translational inhibition of YAP oncogene expression by 4-hydroxynonenal in bladder cancer cells
Autor:
Margherita Grattarola, Arianna Carolina Rosa, Alessandra Compagnone, Rosa Maria Pascale, Antonella Roetto, Chiara Dianzani, Chiara Ullio, Roberta Cavalli, Martina Daga, Marie Angele Cucci, Stefania Pizzimenti, Monica Argenziano, Antonietta Palmieri, Giuseppina Barrera, Maria Maddalena Simile
The transcriptional regulator YAP plays an important role in cancer progression and is negatively controlled by the Hippo pathway. YAP is frequently overexpressed in human cancers, including bladder cancer. Interestingly, YAP expression and activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c862ccff65527ad3dba660aa53413509
http://hdl.handle.net/2318/1718896
http://hdl.handle.net/2318/1718896
Autor:
Maria Maddalena Simile, Maria Lauda Tomasi, Graziella Peitta, Francesco Feo, Claudio F. Feo, Antonio Cigliano, Stefania Brozzetti, Diego F. Calvisi, Alberto Porcu, Rosa Maria Pascale
Hepatocellular carcinoma (HCC) is characterized by the down-regulation of the liver-specific methyladenosyltransferase 1A (MAT1A) gene, encoding the S-adenosylmethionine synthesizing isozymes MATI/III, and the up-regulation of the widely expressed me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80ef4ddaed978a609e40da1eb2bcb4f
http://hdl.handle.net/11573/1271494
http://hdl.handle.net/11573/1271494