Human AlphoidtetO Artificial Chromosome as a Gene Therapy Vector for the Developing Hemophilia A Model in Mice

Autor: Sergey V. Ponomartsev, Sergey A. Sinenko, Elena V. Skvortsova, Mikhail A. Liskovykh, Ivan N. Voropaev, Maria M. Savina, Andrey A. Kuzmin, Elena Yu. Kuzmina, Alexandra M. Kondrashkina, Vladimir Larionov, Natalay Kouprina, Alexey N. Tomilin

Publikováno v: Cells, Vol 9, Iss 4, p 879 (2020)

Human artificial chromosomes (HACs), including the de novo synthesized alphoidtetO-HAC, are a powerful tool for introducing genes of interest into eukaryotic cells. HACs are mitotically stable, non-integrative episomal units that have a large transge

Externí odkaz: https://doaj.org/article/4f5e0539ddb941dbb6193eff810f3d45

Human Alphoid

Autor: Sergey V, Ponomartsev, Sergey A, Sinenko, Elena V, Skvortsova, Mikhail A, Liskovykh, Ivan N, Voropaev, Maria M, Savina, Andrey A, Kuzmin, Elena Yu, Kuzmina, Alexandra M, Kondrashkina, Vladimir, Larionov, Natalay, Kouprina, Alexey N, Tomilin

Publikováno v: Cells

Human artificial chromosomes (HACs), including the de novo synthesized alphoidtetO-HAC, are a powerful tool for introducing genes of interest into eukaryotic cells. HACs are mitotically stable, non-integrative episomal units that have a large transge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e056ab2f0cf526c73856f138057a80e
https://pubmed.ncbi.nlm.nih.gov/32260189

Rocks in the auxin stream: Wound-induced auxin accumulation and ERF115 expression synergistically drive stem cell regeneration.

Autor: Canher B; Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.; Center for Plant Systems Biology, VIB, B-9052 Ghent, Belgium., Heyman J; Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.; Center for Plant Systems Biology, VIB, B-9052 Ghent, Belgium., Savina M; Department for Systems Biology, Institute of Cytology and Genetics SB RAS, 630090 Novosibirsk, Russia.; LCT & EB, Novosibirsk State University, 630090 Novosibirsk, Russia., Devendran A; Department of Biological Sciences and Centre for BioImaging Sciences, National University of Singapore, Singapore 117543, Singapore., Eekhout T; Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.; Center for Plant Systems Biology, VIB, B-9052 Ghent, Belgium., Vercauteren I; Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.; Center for Plant Systems Biology, VIB, B-9052 Ghent, Belgium., Prinsen E; Integrated Molecular Plant Physiology Research, Department of Biology, University of Antwerp, 2020 Antwerp, Belgium., Matosevich R; Institute of Plant Sciences and Genetics in Agriculture, Faculty of Agriculture, The Hebrew University of Jerusalem, Rehovot 7612001, Israel., Xu J; Department of Plant Systems Physiology, Institute for Water and Wetland Research, Faculty of Science, Radboud University, 6525 AJ Nijmegen, The Netherlands., Mironova V; Department for Systems Biology, Institute of Cytology and Genetics SB RAS, 630090 Novosibirsk, Russia.; LCT & EB, Novosibirsk State University, 630090 Novosibirsk, Russia., De Veylder L; Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium; lieven.deveylder@psb.vib-ugent.be.; Center for Plant Systems Biology, VIB, B-9052 Ghent, Belgium.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 14; Vol. 117 (28), pp. 16667-16677. Date of Electronic Publication: 2020 Jun 29.