Výsledky vyhledávání - "Maria M. Docanto"

Publikováno v: Transl Androl Urol

BACKGROUND: As potent systemic therapies transition earlier in the prostate cancer disease course, molecular biomarkers are needed to guide optimal treatment selection for metastatic hormone-sensitive prostate cancer (mHSPC). The value of whole blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f0bace130d69e45160d4caad46e98cc
https://pubmed.ncbi.nlm.nih.gov/33968657

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Des-acyl ghrelin inhibits the capacity of macrophages to stimulate the expression of aromatase in breast adipose stromal cells

Autor: Heba M. Zahid, Kristy A. Brown, Maria M. Docanto, Richard L. Ferrero, John B. Furness, CheukMan C Au, Francesca Maria Raffaelli

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 170:49-53

Des-acyl ghrelin is the unacylated form of the well-characterized appetite-stimulating hormone ghrelin. It affects a number of physiological processes, including increasing adipose lipid accumulation and inhibiting adipose tissue inflammation. Breast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462dddd2f9bbd6c9dec69916aa650198
https://doi.org/10.1016/j.jsbmb.2016.07.005

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IL-10 suppresses TNF-α-induced expression of human aromatase gene in mammary adipose tissue

Autor: Gabriela, Martínez-Chacón, Kristy A, Brown, Maria M, Docanto, Himanshu, Kumar, Seppo, Salminen, Niina, Saarinen, Sari, Mäkelä

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(6)

White adipose tissue inflammation is linked with increased aromatase gene expression and estrogen production, a major risk factor for breast cancer in obese postmenopausal women. TNF-α, a proinflammatory cytokine, is a key driver of aromatase promot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::306056aa9b2822fc4d85df66408b1ba3
https://pubmed.ncbi.nlm.nih.gov/29401621

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Timeless Is a Novel Estrogen Receptor Co-activator Involved in Multiple Signaling Pathways in MCF-7 Cells

Autor: Morag J. Young, Chantal Beatrice Magne Nde, Colin Clyne, Jakob Buehn, Kevin Christopher Knower, Gloria Casas Gimeno, Edris Sayed, Maria M. Docanto

Publikováno v: Journal of molecular biology. 430(10)

Activation of estrogen receptor α (ERα) stimulates cell division and tumor growth by modulating the expression of ERα target genes. This activation involves the recruitment of specific proteins with activities that are still not fully understood.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4811f4fb27623daa417f4883bbdd3d57
https://pubmed.ncbi.nlm.nih.gov/29555554

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Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase

Autor: Kristy A. Brown, Nicole I. Hunger, Evan R. Simpson, Maria M. Docanto

Publikováno v: Breast Cancer Research and Treatment. 123:591-596

AMP-activated protein kinase (AMPK) is recognized as a master regulator of energy homeostasis. In concert with the AMPK-kinase LKB1, it has been shown to provide a molecular link between obesity and postmenopausal breast cancer via its actions to inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2912957bd7eb5f33a7aea612e78847d6
https://doi.org/10.1007/s10549-010-0834-y

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