Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Maria M Mikedis"'
Autor:
Maria M Mikedis, Yuting Fan, Peter K Nicholls, Tsutomu Endo, Emily K Jackson, Sarah A Cobb, Dirk G de Rooij, David C Page
Publikováno v:
eLife, Vol 9 (2020)
Fertility across metazoa requires the germline-specific DAZ family of RNA-binding proteins. Here we examine whether DAZL directly regulates progenitor spermatogonia using a conditional genetic mouse model and in vivo biochemical approaches combined w
Externí odkaz:
https://doaj.org/article/2312dd28ddac47b695b92a14710794bd
Autor:
Megan A Gura, Maria M Mikedis, Kimberly A Seymour, Dirk G de Rooij, David C Page, Richard N Freiman
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008515 (2020)
Germ cells undergo many developmental transitions before ultimately becoming either eggs or sperm, and during embryonic development these transitions include epigenetic reprogramming, quiescence, and meiosis. To begin understanding the transcriptiona
Externí odkaz:
https://doaj.org/article/621760bfc3a2474c9061383b9789fb7a
Autor:
Y Q Shirleen Soh, Maria M Mikedis, Mina Kojima, Alexander K Godfrey, Dirk G de Rooij, David C Page
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006704 (2017)
The meiosis-specific chromosomal events of homolog pairing, synapsis, and recombination occur over an extended meiotic prophase I that is many times longer than prophase of mitosis. Here we show that, in mice, maintenance of an extended meiotic proph
Externí odkaz:
https://doaj.org/article/d3d9eaae61064bb9bce366404b6f56be
Autor:
Jennifer H. Kong, Claudia G. Vasquez, Sweta Agrawal, Prerna Malaney, Maria M. Mikedis, Andrea B. Moffitt, Lexy von Diezmann, Christina M. Termini
Publikováno v:
Trends in Biochemical Sciences. 48:203-210
The process of evaluating and negotiating a tenure-track job offer is unstructured and highly variable, making it susceptible to bias and inequitable outcomes. We outline common aspects of and recommendations for negotiating an academic job offer in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaae8441370a0d524593336ee5215f12
https://doi.org/10.1016/j.tibs.2022.10.004
https://doi.org/10.1016/j.tibs.2022.10.004
Autor:
Peter K. Nicholls, Maria M. Mikedis, Yuting Fan, Tsutomu Endo, Dirk G. de Rooij, David C. Page, Emily K. Jackson, Sarah A Cobb
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Fertility across metazoa requires the germline-specific DAZ family of RNA-binding proteins. Here we examine whether DAZL directly regulates progenitor spermatogonia using a conditional genetic mouse model and in vivo biochemical approaches combined w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a8aa0d7cc29739a26ee880793eb046
https://elifesciences.org/articles/56523
https://elifesciences.org/articles/56523
Publikováno v:
Biomolecules
Biomolecules, 9(12). Multidisciplinary Digital Publishing Institute (MDPI)
Biomolecules, 9(12). Multidisciplinary Digital Publishing Institute (MDPI)
Retinoic acid (RA), a derivative of vitamin A, is critical for the production of oocytes and sperm in mammals. These gametes derive from primordial germ cells, which colonize the nascent gonad, and later undertake sexual differentiation to produce oo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3a2f5d84f3f2b2f51563aa1be1ede5
http://europepmc.org/articles/PMC6995559
http://europepmc.org/articles/PMC6995559
Autor:
Karen M. Downs, Maria M. Mikedis
Publikováno v:
Developmental Dynamics. 246:50-71
Background: PRDM1 is a transcriptional repressor that contributes to primordial germ cell (PGC) development. During early gastrulation, epiblast-derived PRDM1 is thought to be restricted to a lineage-segregated germ line in the allantois. However, gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e43f54733055e24febffa74b92387bf
https://doi.org/10.1002/dvdy.24461
https://doi.org/10.1002/dvdy.24461
Autor:
Dexter X. Jin, Adam D. Wolfe, Adriana M. Rodriguez, Karen M. Downs, Lauren Wierenga, Christoph Viebahn, Maria M. Mikedis, Maleka P. Hashmi
How the fetal-placental arterial connection is made and positioned relative to the embryonic body axis, thereby ensuring efficient and directed blood flow to and from the mother during gestation, is not known. Here we use a combination of genetics, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1d299b646a41b213e9ed1b6c1326ae
https://europepmc.org/articles/PMC5760991/
https://europepmc.org/articles/PMC5760991/
Autor:
Mina L Kojima, David C. Page, Alexander K. Godfrey, Dirk G. de Rooij, Maria M. Mikedis, Y. Q. Shirleen Soh
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006704 (2017)
PLoS
PLoS Genetics
PLoS
PLoS Genetics
The meiosis-specific chromosomal events of homolog pairing, synapsis, and recombination occur over an extended meiotic prophase I that is many times longer than prophase of mitosis. Here we show that, in mice, maintenance of an extended meiotic proph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9234b8ba7e3093d8c61bb3ec5d0261
http://europepmc.org/articles/PMC5397071?pdf=render
http://europepmc.org/articles/PMC5397071?pdf=render