Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway.

Autor: Márcia M T Moraes, Marcella C Galvão, Danilo Cabral, Cideli P Coelho, Nicolle Queiroz-Hazarbassanov, Maria F M Martins, Eduardo F Bondan, Maria M Bernardi, Thiago Berti Kirsten

Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0169446 (2017)

Recent studies have demonstrated the intimate relationship between depression and immune disturbances. Aware of the efficacy limits of existing antidepressant drugs and the potential anti-inflammatory properties of propentofylline, we sought to evalu

Externí odkaz: https://doaj.org/article/d5c7641a963d46ee93cd95cfa2e1789a

LPS exposure increases maternal corticosterone levels, causes placental injury and increases IL-1Β levels in adult rat offspring: relevance to autism.

Autor: Thiago B Kirsten, Luciana L Lippi, Estela Bevilacqua, Maria M Bernardi

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82244 (2013)

Maternal immune activation can induce neuropsychiatric disorders, such as autism and schizophrenia. Previous investigations by our group have shown that prenatal treatment of rats on gestation day 9.5 with lipopolysaccharide (LPS; 100 μg/kg, intrape

Externí odkaz: https://doaj.org/article/8538f1b3ec894623a360bddfff1225f7

Long-term obesity is associated with depression and neuroinflammation

Autor: Fernanda B. Lorena, Bruna P. P do Nascimento, Esther L. R. A. Camargo, Maria M. Bernardi, André R. Fukushima, Julia do N. Panizza, Paula de B. Nogueira, Marllos E. S. Brandão, Miriam O. Ribeiro

Publikováno v: Archives of Endocrinology and Metabolism, Volume: 65, Issue: 5, Pages: 537-548, Published: 12 NOV 2021
Archives of Endocrinology and Metabolism v.65 n.5 2021
Arquivos de Endocrinologia e Metabolismo
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
Archives of Endocrinology and Metabolism, Vol 65, Iss 5, Pp 537-548 (2021)

Objective: Obesity is characterized by a state of chronic, low-intensity systemic inflammation frequently associated with insulin resistance and dyslipidemia. Materials and methods: Given that chronic inflammation has been implicated in the pathogene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d44e584ff90f65fe8279bae0b565de
https://doi.org/10.20945/2359-3997000000400

Pimozide injections into the Nucleus accumbens disrupt maternal behaviour in lactating rats

Autor: Maria Rita P, Silva, Maria M, Bernardi, Pablo E, Cruz-Casallas, Luciano F, Felicio

Publikováno v: Pharmacologytoxicology. 93(1)

In rodents ongoing maternal behaviour requires activation of dopamine receptors. Therefore, it is possible that some motor components of maternal behaviour might be mediated by concurrent dopaminergic stimulation. It has been previously demonstrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::564883babcf69d8e8df255df76b5e7d2
https://pubmed.ncbi.nlm.nih.gov/12828573

First Chemical Evaluation and Toxicity of Casinga-cheirosa to Balb-c Male Mice

Autor: Dirce M. Estork, Daniela F. Gusmão, Mateus L. B. Paciencia, Ingrit E. C. Díaz, Antonio D. Varella, Riad N. Younes, Luiz F. L. Reis, Edna F. S. Montero, Maria M. Bernardi, Ivana B. Suffredini

Publikováno v: Molecules, Vol 19, Iss 4, Pp 3973-3987 (2014)

Laetia suaveolens, known as “casinga-cheirosa”, crude extract EB719 has previously shown cytotoxic activity against prostate cancer and squamous cell carcinoma. For the first time, seven molecules were isolated from its apolar—α-tocopherol (1)

Externí odkaz: https://doaj.org/article/21bb7abb9aa34cca9d2c5eeb6d668383