Disruption of Interleukin-1β Autocrine Signaling Rescues Complex I Activity and Improves ROS Levels in Immortalized Epithelial Cells with Impaired Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function

Autor: Mariángeles Clauzure, Gustavo Schulman, Tomás A. Santa-Coloma, Ángel G. Valdivieso, Maria Luz Teiber, María Macarena Massip Copiz

Publikováno v: PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE Vol. 9, N° 6, 2014
PLoS ONE, Vol 9, Iss 6, p e99257 (2014)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA

Patients with cystic fibrosis (CF) have elevated concentration of cytokines in sputum and a general inflammatory condition. In addition, CF cells in culture produce diverse cytokines in excess, including IL-1B. We have previously shown that IL-1B, at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45d3c18deaad1cf23c624d14527aa00
http://europepmc.org/articles/PMC4047112