Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Maria Lund"'
Autor:
Dhanusha Sabanathan, Douglas Campbell, Vicki Velonas, Sandra Wissmueller, Hubert Mazure, Marko Trifunovic, Pirooz Poursoltan, Kevin Ho-Shon, Tiffany Mackay, Maria Lund, Yanling Lu, Paul Roach, Dale Bailey, Bradley Walsh, David Gillatt, Howard Gurney
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 9, Iss 2, Pp 86-100 (2021)
Objective(s): Miltuximab® is a chimeric antibody targeting Glypican-1 (GPC-1), a cell surface antigen which is overexpressed in solid cancers. Miltuximab® has shown promising safety and efficacy in radioimmunotherapy models of prostate cancer. This
Externí odkaz:
https://doaj.org/article/e54133442db347f2aa83af2e911eee7d
Autor:
Nham Tran, Alison Ricafrente, Joyce To, Maria Lund, Tania M. Marques, Margarida Gama-Carvalho, Krystyna Cwiklinski, John P. Dalton, Sheila Donnelly
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Fasciola hepatica, a global worm parasite of humans and their livestock, regulates host innate immune responses within hours of infection. Host macrophages, essential to the first-line defence mechanisms, are quickly restricted in their abil
Externí odkaz:
https://doaj.org/article/c491f3abaaee4078b8355327c7eadde9
Autor:
Mei-Chun Yeh, Brian W. C. Tse, Nicholas L. Fletcher, Zachary H. Houston, Maria Lund, Marianna Volpert, Chelsea Stewart, Kamil A. Sokolowski, Varinder Jeet, Kristofer J. Thurecht, Douglas H. Campbell, Bradley J. Walsh, Colleen C. Nelson, Pamela J. Russell
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Purpose Chimeric antibody Miltuximab®, a human IgG1 engineered from the parent antibody MIL-38, is in clinical development for solid tumour therapy. Miltuximab® targets glypican-1 (GPC-1), a cell surface protein involved in tumour growth,
Externí odkaz:
https://doaj.org/article/2ef2c8e3d8664d7a8617ef5010ba309f
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2378 (2021)
In the Arctic, seasonal changes are substantial, and as a result, the marine bacterial community composition and functions differ greatly between the dark winter and light-intensive summer. While light availability is, overall, the external driver of
Externí odkaz:
https://doaj.org/article/d8e79f23059e44a6b8ed15b1fbc6fa6a
Publikováno v:
BMC Immunology, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles through modulation of the expression of genes, especially those encoding cyt
Externí odkaz:
https://doaj.org/article/6470da48e4b442259ace2bfc51f0468f
Autor:
Kalle Olli, Elisabeth Halvorsen, Maria Vernet, Peter J. Lavrentyev, Gayantonia Franzè, Marina Sanz-Martin, Maria Lund Paulsen, Marit Reigstad
Publikováno v:
Frontiers in Marine Science, Vol 6 (2019)
We used inverse modeling to reconstruct major planktonic food web carbon flows in the Atlantic Water inflow, east and north of Svalbard during spring (18–25 May) and summer (9–13 August), 2014. The model was based on three intensively sampled sta
Externí odkaz:
https://doaj.org/article/199d34b386044389a13aa928842eeceb
Autor:
Maria Lund Nielsen, Thomas Isbrandt, Kasper Bøwig Rasmussen, Ulf Thrane, Jakob Blæsbjerg Hoof, Thomas Ostenfeld Larsen, Uffe Hasbro Mortensen
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169712 (2017)
The full potential of fungal secondary metabolism has until recently been impeded by the lack of universal genetic tools for most species. However, the emergence of several CRISPR-Cas9-based genome editing systems adapted for several genera of filame
Externí odkaz:
https://doaj.org/article/88ddcfeb88a14231af9d130847632f5a
Autor:
Ruth-Anne Sandaa, Julia E. Storesund, Emily Olesin, Maria Lund Paulsen, Aud Larsen, Gunnar Bratbak, Jessica Louise Ray
Publikováno v:
Viruses, Vol 10, Iss 12, p 715 (2018)
The Arctic marine environment experiences dramatic seasonal changes in light and nutrient availability. To investigate the influence of seasonality on Arctic marine virus communities, five research cruises to the west and north of Svalbard were condu
Externí odkaz:
https://doaj.org/article/f92d53597c7947729e38f0ff5ac43ab7
Autor:
Maria Lund Paulsen, Hugo Doré, Laurence Garczarek, Lena Seuthe, Oliver Müller, Ruth-Anne Sandaa, Gunnar Bratbak, Aud Larsen
Publikováno v:
Frontiers in Marine Science, Vol 3 (2016)
Increasing temperatures, with pronounced effects at high latitudes, have raised questions about potential changes in species composition, as well as possible increased importance of small-celled phytoplankton in marine systems. In this study, we mapp
Externí odkaz:
https://doaj.org/article/035bb31fcd154b15971c7cad98152293