Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maria Luiza M, Silva"'
Autor:
Roberto R.C. de Matos, Gerson M. Ferreira, Claus Meyer, Rolf Marschalek, Patrizia Larghero, Raul C. Ribeiro, Thomas Liehr, Moneeb Othman, Mariana T. de S.M. Bizarro, Elaine Sobral da Costa, Marcelo G.P. Land, Eliana Abdelhay, Renata Binato, Maria Luiza M. Silva
Publikováno v:
Journal of Pediatric Hematology/Oncology. 44:e719-e722
About 25% of the patients with the translocation t(11;19)(q23;p13.3)/KMT2A-MLLT1 present three-way or more complex fusions, associated with a worse prognosis, suggesting that a particular mechanism creates functional KMT2A fusions for this condition.
Autor:
Roberto R, Capela de Matos, Daniela R, Ney Garcia, Moneeb A K, Othman, Gerson, Moura Ferreira, Joana B, Melo, Isabel M, Carreira, Claus, Meyer, Rolf, Marschalek, Elaine S, Costa, Marcelo G P, Land, Thomas, Liehr, Raul C, Ribeiro, Maria Luiza M, Silva
Publikováno v:
Cytogenetic and genome research. 157(4)
Patients with childhood acute myeloid leukemia (AML) with complex karyotypes (CKs) have a dismal outcome. However, for patients with a KMT2A rearrangement (KMT2A-r), the prognosis appears to depend on the fusion partner gene rather than the karyotype
Autor:
Roberto R, Capela de Matos, Daniela R, Ney Garcia, Elaine, Cifoni, Moneeb A K, Othman, Mariana, Tavares de Souza, Edna K, Carboni, Gerson M, Ferreira, Thomas, Liehr, Raul C, Ribeiro, Maria Luiza, M Silva
Publikováno v:
Cytogenetic and genome research. 152(1)
Pediatric acute myeloid leukemia (AML) is a highly heterogeneous disease, presenting cytogenetic and molecular abnormalities which turned out to be critical prognostic factors. Ploidy changes as gain or loss of individual chromosomes are rare in AML,
Autor:
Maria Luiza M. Silva, Aloisio N. Valente, Lisselot Laun, Luis Fernando Bouzas, Maria S. Pombo de Oliveira, Raul C. Ribeiro, Eliana F. Ss Abdelhay
Publikováno v:
Cancer Genetics and Cytogenetics. 56:171-176
A t(11;14)(p15;q11) was the sole chromosome abnormality observed in the malignant cells of a 10-year-old boy with acute leukemia. Morphologically, these cells were classified as L1 by the criteria of the French-American-British Working Group. Cytoche