Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maria Luisa Veronese"'
Autor:
Jason E. Faris, Eli L. Diamond, Martina Makrutzki, Vivek Subbiah, Antoine Hollebecque, Maria Luisa Veronese, Maria Elena Elez-Fernandez, David M. Hyman, Radj Gervais, Juergen Wolf, Josep Tabernero, Igor Puzanov, Susan Frances Lasserre, Noopur Raje, Martin Schuler, Jean-Yves Blay, José Baselga, Emily Chan, Ian Chau, Ralf-Dieter Hofheinz, Florin Sirzen, Manuel Hidalgo, Antoine Italiano
BackgroundBRAF V600 mutations occur in various nonmelanoma cancers. We undertook a histology-independent phase 2 “basket” study of vemurafenib in BRAF V600 mutation–positive nonmelanoma cancers. MethodsWe enrolled patients in six prespecified c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db07b26d091caa624e875997ead64da8
http://europepmc.org/articles/pmc4971773
http://europepmc.org/articles/pmc4971773
Autor:
Howard E. Greenberg, Lisa Gillen, Scott A. Waldman, Maria Luisa Veronese, Walter W. Hauck, Ellen P. Dorval
Publikováno v:
The Journal of Clinical Pharmacology. 43:1091-1100
Mibefradil, a calcium channel blocker, was removed from the market because of adverse drug interactions with coadministered CYP3A4 substrates. This study examined the effect of mibefradil on the activity of hepatic and intestinal CYP3A4 in vivo, empl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229aee140443d836d3efb2a6477c14ee
https://doi.org/10.1177/0091270003256687
https://doi.org/10.1177/0091270003256687
Autor:
Scott A. Waldman, Ed Pequignot, Howard E. Greenberg, Joanne Burke, Walter W. Hauck, Ellen P. Dorval, Maria Luisa Veronese, Lisa Gillen
Publikováno v:
The Journal of Clinical Pharmacology. 43:831-839
Consumption of typical quantities of grapefruit juice (GFJ) increases the oral bioavailability of several CYP3A4 substrates without affecting their elimination, consistent with selective inhibition of intestinal but not hepatic CYP3A4. However, incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba13a4d44b2e188ecc39324f3385b3bf
https://doi.org/10.1177/0091270003256059
https://doi.org/10.1177/0091270003256059
Autor:
Tapani Ruutu, Matthew P. Strout, Maria Luisa Veronese, Karl S. Theil, Ralf Krahe, Clara D. Bloomfield, Carlo M. Croce, Sakari Knuutila, Michael A. Caligiuri, Brian Becknell, Peter J. Kourlas
Publikováno v:
Proceedings of the National Academy of Sciences. 97:2145-2150
We have identified a gene at 11q23, telomeric to MLL , that encodes a guanine nucleotide exchange factor (GEF). This gene is transcribed into a 9.5-kb mRNA containing a 4.6-kb ORF. By Northern analysis, it was found to be expressed in all human tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19466152806625a1dccdc9a5ac99b6fe
https://doi.org/10.1073/pnas.040569197
https://doi.org/10.1073/pnas.040569197
Autor:
Maria Luisa Veronese, Antonella Bardi, Antonio Cuneo, G. L. Scapoli, Gian Matteo Rigolin, Massimo Negrini, Carlo M. Croce, Florencia Bullrich, Maria Grazia Roberti, Gian Luigi Castoldi, Renato Bigoni, R Spanedda, N Piva
Publikováno v:
Scopus-Elsevier
To define better the chromosomal profile of atypical chronic lymphocytic leukemia (aCLL), cytogenetic and interphase cytogenetic studies were performed in 43 cases, using mitogen-stimulated cultures and DNA probes detecting the two most frequently oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769f5827f11939ae90ef53662ec13d31
https://doi.org/10.1038/sj.leu.2400818
https://doi.org/10.1038/sj.leu.2400818
Autor:
Maria Luisa Veronese, Michael A. Caligiuri, John C. Reed, Shinichi Kitada, Florencia Bullrich, Carlo M. Croce, Jesper Jurlander
Publikováno v:
Blood. 88:3109-3115
Allelic loss at nonrandom chromosomal sites is thought to mark the position of tumor suppressor genes involved in the pathogenesis and progression of human malignancies. Solid tumors in particular have been found to harbor multiple genetic changes re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8330b2ebc6dbf8d51b0147c12947acbc
https://doi.org/10.1182/blood.v88.8.3109.bloodjournal8883109
https://doi.org/10.1182/blood.v88.8.3109.bloodjournal8883109
Publikováno v:
Current Opinion in Oncology. 8:346-352
The biologic and clinical heterogeneity of lymphomas represents the major obstacle to their diagnosis. Because histologic analysis, which is the initial diagnostic approach, has been demonstrated to be insufficient in the definition of certain types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4865bc502f9b615b36d6459593acf5b
https://doi.org/10.1097/00001622-199609000-00002
https://doi.org/10.1097/00001622-199609000-00002
Autor:
Kay Huebner, Arthur M. Buchberg, John L. Knopf, Linda D. Siracusa, Maria Luisa Veronese, Alysia C. Argeson, Teresa Druck
Publikováno v:
Genomics. 25:29-35
The phospholipase C {gamma}-2 (Plcg2) gene encodes an enzyme that plays a crucial role in intracellular signal transduction pathways. This enzyme is important because of its role in the generation of second messengers following the hydrolysis of phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6659b034afdce8a22370b60bee0c3eda
https://doi.org/10.1016/0888-7543(95)80106-v
https://doi.org/10.1016/0888-7543(95)80106-v
Autor:
Maria Luisa Veronese, Florin Sirzen, Ian Chau, Igor Puzanov, Jean-Yves Blay, Lada Mitchell, Maria Elena Elez Fernandez, José Baselga, David M. Hyman, Juergen Wolf, Noopur Raje
Publikováno v:
Journal of Clinical Oncology. 32:2533-2533
2533^ Background: Low prevalence of V600m in non-melanoma cancers requires a novel trial design to assess the activity of BRAF inhibitors. We undertook a histology-independent, “basket” study of VE...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19b50558fd0002469ab0cf9b4dd7da44
https://doi.org/10.1200/jco.2014.32.15_suppl.2533
https://doi.org/10.1200/jco.2014.32.15_suppl.2533
Autor:
Antonella Bardi, Renato Bigoni, Hartmut Döhner, Carlo M. Croce, Gianluigi Castoldi, N Piva, Maria Grazia Roberti, Françoise Birg, Gian Matteo Rigolin, Florencia Bullrich, Antonio Cuneo, Anne Hagemeijer, Maria Luisa Veronese, Raffaella Milani
Publikováno v:
Scopus-Elsevier
Conventional chromosome analysis (CCA) and interphase fluorescence in situ hybridization (FISH) was performed in 42 patients with mantle-cell lymphoma (MCL), with BCL1 rearrangement. The t(11;14)(q13;q32) or 11q abnormalities were detected by CCA in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70921f35d568519f102e642e7cf8cff2
http://hdl.handle.net/11392/1199435
http://hdl.handle.net/11392/1199435