Zobrazeno 1 - 10 of 78 pro vyhledávání: '"Maria Luisa Del Rio"'
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Akademický článek
Genetic deletion of HVEM in a leukemia B cell line promotes a preferential increase of PD-1- stem cell-like T cells over PD-1+ T cells curbing tumor progression
Autor: Maria-Luisa del Rio, Carla Yago-Diez de Juan, Giovanna Roncador, Eduardo Caleiras, Ramón Álvarez-Esteban, José Antonio Pérez-Simón, Jose-Ignacio Rodriguez-Barbosa
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionA high frequency of mutations affecting the gene encoding Herpes Virus Entry Mediator (HVEM, TNFRSF14) is a common clinical finding in a wide variety of human tumors, including those of hematological origin.MethodsWe have addressed how HV
Externí odkaz: https://doaj.org/article/d45f1aac1da2426b84b5c0a30178393d
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2
Akademický článek
Differential Engraftment of Parental A20 PD-L1 WT and PD-L1 KO Leukemia Cells in Semiallogeneic Recipients in the Context of PD-L1/PD-1 Interaction and NK Cell-Mediated Hybrid Resistance
Autor: Maria-Luisa del Rio, Jose-Antonio Perez-Simon, Jose-Ignacio Rodriguez-Barbosa
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
The contribution of natural killer (NK) cells to tumor rejection in the context of programmed death-ligand 1/programmed death 1 (PD-L1/PD-1) blockade is a matter of intense debate. To elucidate the role of PD-L1 expression on tumor cells and the func
Externí odkaz: https://doaj.org/article/da92a9f3e21f4316a03f8698e48841af
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3
Akademický článek
The Role of the Inhibitory Ligand HVEM and Its Receptors CD160 and BTLA in the Regulation of Anti-retroviral T Cell Responses
Autor: Paul David, Jaana Westmeier, Malgorzata Drabczyk-Pluta, Tanja Werner, Julia Ickler, Sandra Francois, Wibke Bayer, Kathrin Sutter, Maria Luisa Del Rio, Jose-Ignacio Rodriguez-Barbosa, Ulf Dittmer, Gennadiy Zelinskyy
Publikováno v: Frontiers in Virology, Vol 2 (2022)
Specific CD8+ T cells are crucial for the control of viruses. However, during many chronic viral infections these cells become dysfunctional. Immune checkpoint receptors, like PD-1 expressed on CD8+ T cells, contribute to this functional suppression
Externí odkaz: https://doaj.org/article/b159ccee1050406998b106e8b901a932
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4
Akademický článek
CD160 serves as a negative regulator of NKT cells in acute hepatic injury
Autor: Tae-Jin Kim, Gayoung Park, Jeongmin Kim, Seon Ah Lim, Jiyoung Kim, Kyungtaek Im, Min Hwa Shin, Yang-Xin Fu, Maria-Luisa Del Rio, Jose-Ignacio Rodriguez-Barbosa, Cassian Yee, Kyung-Suk Suh, Seong-Jin Kim, Sang-Jun Ha, Kyung-Mi Lee
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
BTLA is established as a negative regulator of natural killer T (NKT) cell function, and share its ligand HVEM with CD160. Here the authors show, by analyzing NKT activation in CD160-deficient mice or with BTLA blockade, that CD160 synergizes with BT
Externí odkaz: https://doaj.org/article/c01494c358d541df8aa8b760a2cb9a37
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5
Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor model
Autor: Jose-Antonio Perez-Simon, Jose-Ignacio Rodriguez-Barbosa, Miyuki Azuma, Gennadiy Zelinskyy, Maria-Luisa del Rio
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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The expression of PD-L1 on tumor cells or within the tumor microenvironment has been associated with good prognosis and sustained clinical responses in immunotherapeutic regimens based on PD-L1/PD-1/CD80 immune checkpoint blockade. To look into the c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da22716853e4071139c9016001a62f3b
https://doi.org/10.1007/s00262-020-02520-z
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6
The impact of CD160 deficiency on alloreactive CD8 T cell responses and allograft rejection
Autor: Laurent Tesson, Jean-Marie Heslan, Raúl Fernández-González, Ignacio Anegon, Julia L. Gutiérrez-Arroyo, Alfonso Gutiérrez-Adán, Leo Buhler, José A. Pérez-Simón, Jose-Ignacio Rodriguez-Barbosa, Tuan H. Nguyen, Maria-Luisa del Rio
Publikováno v: BULERIA. Repositorio Institucional de la Universidad de León
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[EN] CD160 is a member of the immunoglobulin superfamily with a pattern of expression mainly restricted to cytotoxic cells. To assess the functional relevance of the HVEM/CD160 signaling pathway in allogeneic cytotoxic responses, exon 2 of the CD160
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fe17c4b65a7b0c640a7276a7099f53
http://hdl.handle.net/20.500.12792/6224
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7
Identification of Hypoderma actaeon (Diptera: Oestridae) in red deer ( Cervus elaphus ) from northern Spain: Microscopy study and molecular analysis
Autor: Sara González, Maria Luisa Del Rio, Maria Natividad Diez, Maria del Rosario Hidalgo, Angelica Martínez
[EN] Hypoderma spp. larvae were observed subcutaneously in the dorsal and lumbar regions of red deer (Cervus elaphus) hunted in the province of León (northwestern Spain) causing a myiasis. They were removed and initially classified by their size, sh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bc6c0f5d1aa65e6f4e8fbaddf39d89
http://hdl.handle.net/10612/15386
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8
Balance between Hosts and Guests: The Key to Sustainable Tourism in a Heritage City
Autor: Manuel Rama, Emilio Carral, Sara González-García, Elías Torres-Feijó, Maria Luisa del Rio, María Teresa Moreira, Gumersindo Feijoo
Publikováno v: Sustainability; Volume 14; Issue 20; Pages: 13253
A sustainable city implies socio-economic characteristics that allow citizens to maintain a certain quality of life. However, the effect of overtourism in some tourist cities negatively affects the community. In this study, a methodology was develope
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f046033d8580c972886477be63a5cd64
https://doi.org/10.3390/su142013253
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10
The role of TNFR2 and DR3 in the in vivo expansion of tregs in T Cell depleting transplantation regimens
Autor: Pascal Schneider, Leo Buhler, Luis Graca, Jose-Ignacio Rodriguez-Barbosa, José A. Pérez-Simón, Maria-Luisa del Rio
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3347, p 3347 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
This article belongs to the Special Issue Trends in Molecular Research for Transplantation Immunology.
Regulatory T cells (Tregs) are essential for the maintenance of tolerance to self and non-self through cell-intrinsic and cell-extrinsic mecha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3c376efdeb9af44f8cec3cbe3e6a33
https://hdl.handle.net/10451/46428
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