Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maria Luisa Campo"'
A disulfide bond in the TIM23 complex is crucial for voltage gating and mitochondrial protein import
Autor:
Maria Luisa Campo, Martin van der Laan, Johannes M. Herrmann, Valentina Peleh, Sonia Martinez-Caballero, Michael Schroda, Florian Wollweber, R. Todd Alexander, Ajay Ramesh, Frederik Sommer
Publikováno v:
The Journal of Cell Biology
Here, Ramesh et al. show that import and oxidation of Tim17, a membrane-embedded subunit of the mitochondrial protein import machinery, are mediated by the mitochondrial disulfide relay, although its disulfide bond is formed differently than soluble
Publikováno v:
Jornal de Assistência Farmacêutica e Farmacoeconomia, Vol 8, Iss s. 2 (2023)
Introdução: No Brasil, a dispensação de medicamentos para o tratamento da AR é feita por meio do Componente Básico da Assistência Farmacêutica (analgésico e anti-inflamatórios) e do Componente Especializado da Assistência Farmacêutica (CE
Externí odkaz:
https://doaj.org/article/51d042b55fe142e5a82bb15bd0baf32d
Autor:
Thomas Becker, Alessia Floerchinger, Christoph U. Mårtensson, Martin Philipp Dieterle, Nikolaus Pfanner, Kim Nguyen Doan, Maria Luisa Campo, Lars Ellenrieder
Publikováno v:
Molecular Cell. 73:1056-1065.e7
The mitochondrial inner membrane harbors a large number of metabolite carriers. The precursors of carrier proteins are synthesized in the cytosol and imported into mitochondria by the translocase of the outer membrane (TOM) and the carrier translocas
Publikováno v:
Journal of bioenergetics and biomembranes. 49(1)
The discovery of very large channels in the two membranes of mitochondria represented an astonishing finding and a turning point in the awareness of these conspicuous energy-generating organelles. Sizable channels are at the crossroads of important c
Autor:
Alejandro Gallardo-Soler, Chaitra Marathe, Antonio Castrillo, Maria Luisa Campo, Carlos Gómez-Nieto, Peter Tontonoz, Inés Corraliza
Publikováno v:
Molecular Endocrinology. 22:1394-1402
Macrophages are phagocytic cells that play essential roles in innate immunity and lipid homeostasis. The uptake of modified lipoproteins is an important early event in the development of atherosclerosis. We analyzed the ability of modified low-densit
Autor:
Pablo M. Peixoto, Isabel Monroy, I. Molano, Eloy Redondo, Pilar Parra, Virginia Iniesta, Marina Mangas, Inés Corraliza, Jesualdo Carcelén, C.G. Nieto, Maria Luisa Campo
Publikováno v:
Infection and Immunity. 73:6085-6090
In a previous work, we demonstrated that the induction of arginase I favored the replication ofLeishmaniainside macrophages. Now we have analyzed the differential expression of this enzyme in the mouse model ofL. majorinfection. Ours results show tha
Publikováno v:
Europe PubMed Central
Cerebellar granule neurons in primary culture underwent apoptosis when exposed to C 2 -ceramide. Addition of exogenous phosphatidylcholine (PtdCho) resulted in a dose-dependent full prevention of neuronal death. Exogenous PtdCho also prevented apopto
Publikováno v:
Journal of Bioenergetics and Biomembranes. 32:47-54
All but a small fraction of the hundreds of proteins in a mitochondrion are synthesized in thecytoplasm and imported into the organelle. Water-filled channels are integral to the process oftranslocating proteins since channels can provide an aqueous
Publikováno v:
Archives of Biochemistry and Biophysics. 366:107-115
We have reported that the signal presequence of cytochrome oxidase subunit IV from Neurospora crassa increases the permeability of isolated rat liver mitochondria [P. M. Sokolove and K. W. Kinnally (1996) Arch. Biochem. Biophys. 336, 69] and regulate
Publikováno v:
Journal of Bioenergetics and Biomembranes. 29:223-231
The respiratory uncouplers carbonyl cyanide p-trifluoromethoxyphenylhydrazone (FCCP) and carbonyl cyanide m-chlorophenylhydrazone (CCCP) affect the activities of two mitochondrial ion channels from mouse liver. At micromolar concentrations, the pheny