Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria Luisa, Introvigne"'
Autor:
Maria Luisa Introvigne, Trevor J. Beardsley, Micah C. Fernando, David A. Leonard, Bradley J. Wallar, Susan D. Rudin, Magdalena A. Taracila, Philip N. Rather, Jennifer M. Colquhoun, Shaina Song, Francesco Fini, Kristine M. Hujer, Andrea M. Hujer, Fabio Prati, Rachel A. Powers, Robert A. Bonomo, Emilia Caselli
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 644 (2023)
Acinetobacter baumannii is a Gram-negative organism listed as an urgent threat pathogen by the World Health Organization (WHO). Carbapenem-resistant A. baumannii (CRAB), especially, present therapeutic challenges due to complex mechanisms of resistan
Externí odkaz:
https://doaj.org/article/0bf39937c44f473185677dc4d7075b7e
Autor:
Tahani A. Alsenani, María Margarita Rodríguez, Barbara Ghiglione, Magdalena A. Taracila, Maria F. Mojica, Laura J. Rojas, Andrea M. Hujer, Gabriel Gutkind, Christopher R. Bethel, Philip N. Rather, Maria Luisa Introvigne, Fabio Prati, Emilia Caselli, Pablo Power, Focco van den Akker, Robert A. Bonomo
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Design of novel β-lactamase inhibitors (BLIs) is one of the currently accepted strategies to combat the threat of cephalosporin and carbapenem resistance in Gram-negative bacteria. B oronic a cid t ransition s tate i nhibitors (BATSIs) are competiti
Autor:
Mattia Stucchi, Alessandro Zanni, Maria Luisa Introvigne, Francesco Fini, Emilia Caselli, Fabio Prati
Publikováno v:
Organicbiomolecular chemistry. 19(30)
A straightforward concise synthesis of chiral non-racemic aliphatic α-boryl isocyanides, relay intermediates for boron-based bioactive molecules in multicomponent reactions, is presented. The short synthetic sequence comprises as key steps copper-ca
Autor:
Emilia, Caselli, Francesco, Fini, Maria Luisa, Introvigne, Mattia, Stucchi, Magdalena A, Taracila, Erin R, Fish, Kali A, Smolen, Philip N, Rather, Rachel A, Powers, Bradley J, Wallar, Robert A, Bonomo, Fabio, Prati
Publikováno v:
ACS Infectious Diseases
Boronic acid transition state inhibitors (BATSIs) are known reversible covalent inhibitors of serine β-lactamases. The selectivity and high potency of specific BATSIs bearing an amide side chain mimicking the β-lactam’s amide side chain are an es
Publikováno v:
ChemMedChem
Boronic acids are known reversible covalent inhibitors of serine β-lactamases. The selectivity and high potency of specific boronates bearing an amide side chain that mimics the β- lactam’s amide side chain have been advanced in several studies.
Autor:
Bradley J. Wallar, Rachel A. Powers, Francesco Fini, Philip N. Rather, Fabio Prati, Erin R. Fish, Maria Luisa Introvigne, Robert A. Bonomo, Mattia Stucchi, Kali A. Smolen, Magdalena A. Taracila, Emilia Caselli
Boronic acid transition state inhibitors (BATSIs) are known reversible covalent inhibitors of serine β-lactamases. The selectivity and high potency of specific BATSIs bearing an amide side chain mimicking the β-lactam's amide side chain are an esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216e83087d08f3162ebae8cbb64b0670
https://hdl.handle.net/11380/1208053
https://hdl.handle.net/11380/1208053