Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Maria Luigia De Bonis"'
Publikováno v:
Stem Cell Reports, Vol 2, Iss 5, Pp 690-706 (2014)
The NAD-dependent deacetylase SIRT1 is involved in chromatin silencing and genome stability. Elevated SIRT1 levels in embryonic stem cells also suggest a role for SIRT1 in pluripotency. Murine SIRT1 attenuates telomere attrition in vivo and is recrui
Externí odkaz:
https://doaj.org/article/6b824ab0008e4c66b2d400a47376f4b6
Autor:
Maria Rosaria Matarazzo, Francesca Lembo, Tiziana Angrisano, Esteban Ballestar, Marcella Ferraro, Raffaela Pero, Maria Luigia De Bonis, Carmelo Bruno Bruni, Manel Esteller, Maurizio D'Esposito, Lorenzo Chiariotti
Publikováno v:
BioTechniques, Vol 37, Iss 4, Pp 666-673 (2004)
The three-way connection between DNA methylation, chromatin configuration, and transcriptional regulation is under increasing attention, but the fine rules governing the epi-genetic control are still poorly understood. In several studies, the authors
Externí odkaz:
https://doaj.org/article/6d793d280fdb4cf884e718bfef00fe22
Autor:
Bianca Bertulat, Maria Luigia De Bonis, Floriana Della Ragione, Anne Lehmkuhl, Manuela Milden, Christian Storm, K Laurence Jost, Simona Scala, Brian Hendrich, Maurizio D'Esposito, M Cristina Cardoso
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47848 (2012)
The X-linked Mecp2 is a known interpreter of epigenetic information and mutated in Rett syndrome, a complex neurological disease. MeCP2 recruits HDAC complexes to chromatin thereby modulating gene expression and, importantly regulates higher order he
Externí odkaz:
https://doaj.org/article/ad3852ac307e4de68d3069b3c3ab8e90
Autor:
Amelia Cimmino, Rosanna Capasso, Fabbri Muller, Irene Sambri, Lucia Masella, Marianna Raimo, Maria Luigia De Bonis, Stefania D'Angelo, Vincenzo Zappia, Patrizia Galletti, Diego Ingrosso
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3258 (2008)
BACKGROUND:Natural proteins undergo in vivo spontaneous post-biosynthetic deamidation of specific asparagine residues with isoaspartyl formation. Deamidated-isomerized molecules are both structurally and functionally altered. The enzyme isoaspartyl p
Externí odkaz:
https://doaj.org/article/fb687f48569f4a148a1aee47bab3fc1a
Publikováno v:
Stem Cell Reports, Vol 2, Iss 5, Pp 690-706 (2014)
Stem Cell Reports
Stem Cell Reports
Summary The NAD-dependent deacetylase SIRT1 is involved in chromatin silencing and genome stability. Elevated SIRT1 levels in embryonic stem cells also suggest a role for SIRT1 in pluripotency. Murine SIRT1 attenuates telomere attrition in vivo and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3793637f7151ebf8563c54fa05d4c103
http://www.sciencedirect.com/science/article/pii/S2213671114000812
http://www.sciencedirect.com/science/article/pii/S2213671114000812
Autor:
Maria Luigia De Bonis, Manuel Serrano, Susana Velasco, Maria A. Blasco, Jose A Palacios, Daniel Herranz
Publikováno v:
The Journal of Cell Biology
The Journal of Cell Biology; Vol 191
The Journal of Cell Biology; Vol 191
SIRT1 is a positive regulator of telomere length and attenuates age-associated telomere shortening.
Yeast Sir2 deacetylase is a component of the silent information regulator (SIR) complex encompassing Sir2/Sir3/Sir4. Sir2 is recruited to telomer
Yeast Sir2 deacetylase is a component of the silent information regulator (SIR) complex encompassing Sir2/Sir3/Sir4. Sir2 is recruited to telomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd4f5cb28935237996b49a7fdddecc0
https://doi.org/10.1083/jcb.201005160
https://doi.org/10.1083/jcb.201005160
Accumulation of altered aspartyl residues in erythrocyte proteins from patients with Down's syndrome
Autor:
Marianna Raimo, Alvara Sorrentino, Generoso Andria, Patrizia Galletti, Iris Scala, Diego Ingrosso, Antimo D'Aniello, Stefania D'Angelo, Vincenzo Zappia, Maria Luigia De Bonis
Publikováno v:
FEBS Journal. 274:5263-5277
Spontaneous protein deamidation of labile Asn residues, generating L-isoaspartates and D-aspartates, is associated with cell aging and is enhanced by an oxidative microenvironment; to minimize the damage, the isoaspartate residues can be 'repaired' b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba2f0740f3fac63d8b1f00bcd8dfa28
https://doi.org/10.1111/j.1742-4658.2007.06048.x
https://doi.org/10.1111/j.1742-4658.2007.06048.x
Autor:
Isabel López de Silanes, Osvaldo Graña, Maria A. Blasco, David G. Pisano, Maria Luigia De Bonis, Orlando Domínguez
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Telomeric RNAs (TERRAs) are UUAGGG repeat-containing RNAs that are transcribed from the subtelomere towards the telomere. The precise genomic origin of TERRA has remained elusive. Using a whole-genome RNA-sequencing approach, we identify novel mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5e86887722d764398c6c0205e6b4d3
http://hdl.handle.net/20.500.12105/11351
http://hdl.handle.net/20.500.12105/11351
Autor:
Floriana Della Ragione, Seema Dhanjal, Alessandra Renieri, Giuseppe Hayek, Alison Kerr, Stefania Bigoni, Ilaria Meloni, Cecilia Trabanelli, Marcella Vacca, Maj Hultén, Francesco Filippini, Maria Luigia De Bonis, Elisa Manzati, Alessandra Ferlini, Elisa Calzolari, Grazia Mercadante, Michele D'Urso, Michele Zappella, Giorgio Pini, Alberta Budillon, Valeria Rossi, Fiona Macdonald, Maurizio D'Esposito, Francesca Gualandi
Publikováno v:
Università degli Studi di Siena-IRIS
Rett syndrome (RTT) is an X-linked dominant neurological disorder, which appears to be the most common genetic cause of profound combined intellectual and physical disability in Caucasian females. This syndrome has been associated with mutations of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb35b052f47c537d488713a6e0c575a
https://doi.org/10.1016/s0387-7604(01)00343-6
https://doi.org/10.1016/s0387-7604(01)00343-6
Autor:
Anne Lehmkuhl, Maria Luigia De Bonis, Manuela Milden, Maurizio D'Esposito, M. Cristina Cardoso, Simona Scala, Brian Hendrich, Floriana Della Ragione, Christian Storm, K. Laurence Jost, Bianca Bertulat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e47848 (2012)
PLoS ONE, Vol 7, Iss 10, p e47848 (2012)
The X-linked Mecp2 is a known interpreter of epigenetic information and mutated in Rett syndrome, a complex neurological disease. MeCP2 recruits HDAC complexes to chromatin thereby modulating gene expression and, importantly regulates higher order he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92614d195fabdf7f190a9ebffdf223b
http://europepmc.org/articles/PMC3480415
http://europepmc.org/articles/PMC3480415