Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria Lourdes Regina Hughes"'
Autor:
Jichang Li, Wei Xu, Rui Wang, Ziyin Lu, Li Li, Maria Lourdes Regina Hughes, Jinli Wang, Guozheng Jiang, Jian Li, Yuan Sun, Xueping Chen, Chunli Xia, Daoyuan Xie, Rui Li, Ling Zhang, Feng Qian
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:5294-5301
The mechanism of colistin-induced neurotoxicity is still unknown. Our recent study (L. Zhang, Y. H. Zhao, W. J. Ding, G. Z. Jiang, Z. Y. Lu, L. Li, J. L. Wang, J. Li, and J. C. Li, Antimicrob Agents Chemother 59:2189–2197, 2015, http://dx.doi.org/1
Autor:
Martin J. Scanlon, Biswaranjan Mohanty, Rahul Patil, Martin Williams, Stephen J. Headey, Maria Lourdes Regina Hughes, Aisha Laguerre, Christopher J.H. Porter, Jerome Wielens
Publikováno v:
ACS Chemical Biology. 9:2526-2534
The aqueous cytoplasm of cells poses a potentially significant barrier for many lipophilic drugs to reach their sites of action. Fatty acid binding proteins (FABPs) bind to poorly water-soluble fatty acids (FAs) and lipophilic compounds and facilitat
Autor:
Maria Lourdes Regina Hughes, David A. Jans, Martin J. Scanlon, Tony Velkov, Kylie M. Wagstaff, Rahul Chandrakant Patil, Christopher J.H. Porter, Nigel W. Bunnett, Bonan Liu, Michelle L. Halls
Publikováno v:
The Journal of biological chemistry. 290(22)
Nuclear hormone receptors (NHRs) regulate the expression of proteins that control aspects of reproduction, development and metabolism, and are major therapeutic targets. However, NHRs are ubiquitous and participate in multiple physiological processes
Autor:
Philip M Beart, Maria Lourdes Regina Hughes, Percy W.Y. Chu, Linda D Mercer, Phillip Nagley, Liubov Kardashsyan, Chew L. Lau, Yea Seul Shin, Shanti Diwakarla
Publikováno v:
Journal of neurochemistry. 109
GABAergic striatal neurons are compromised in basal ganglia pathologies and we analysed how insult nature determined their patterns of injury and recruitment of the intrinsic mitochondrial pathway during programmed cell death (PCD). Stressors affecti
Publikováno v:
Cellular and molecular life sciences : CMLS. 66(1)
Programmed cell death contributes to neurological diseases and may involve mitochondrial dysfunction with redistribution of apoptogenic proteins. We examined neuronal death to elucidate whether the intrinsic mitochondrial pathway and the crosstalk be