Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maria Lodeiro"'
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4686 (2009)
The aim of the present study was to identify the signaling mechanisms to ghrelin-stimulated activation of the serine/threonine kinase Akt. In human embryonic kidney 293 (HEK293) cells transfected with GHS-R1a, ghrelin leads to the activation of Akt t
Externí odkaz:
https://doaj.org/article/f2faa9b03e464155b94f9a271a83b111
Autor:
Ateeb Farooqui, Roger Morrell, Jiyu Wu, Louise Wright, Maria Lodeiro, Mark Whiting, Michael Pekris, Theo Saunders
Publikováno v:
International Journal of Thermophysics. 44
Autor:
Mariana A Romão, Laura Mateos, Raúl Loera-Valencia, Angel Cedazo-Minguez, Maria Lodeiro, Elena Puerta, Muhammad-Al-Mustafa Ismail, Cláudio M. Gomes, Ingemar Björkhem, Paula Merino-Serrais, Julen Goikolea, Silvia Maioli
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Neurobiology
instname
Molecular Neurobiology
Alterations in cholesterol metabolism in the brain have a major role in the physiology of Alzheimer’s disease (AD). Oxysterols are cholesterol metabolites with multiple implications in memory functions and in neurodegeneration. Previous studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71650c5e01bc7baeadbbb8562a3b5ca
http://hdl.handle.net/10261/261869
http://hdl.handle.net/10261/261869
Autor:
Laura Mateos, Paula Merino-Serrais, Silvia Maioli, Eran Leitersdorf, Muhammad-Al-Mustafa Ismail, Lars Olof-Wahlund, Balázs Gulyás, Zeina Ali, Eric Westman, Maria Lodeiro, Irina Savitcheva, Ingemar Björkhem, Angel Cedazo-Minguez, Bengt Winblad
Publikováno v:
The Journal of Experimental Medicine
Ismail et al. show that 27-hydroxycholesterol, a peripheral cholesterol metabolite capable of passing the blood–brain barrier, reduces brain glucose uptake by upregulating the renin-angiotensin system and inhibiting GLUT4. This alteration affects m
Autor:
María J. Ramírez, Francisco J. Gil-Bea, Eric Westman, Wasim Khan, Paula Merino-Serrais, Silvia Maioli, Farshad Falahati, Roberto Rimondini, Maria Lodeiro, Angel Cedazo-Minguez, Elena Puerta, Andrew Simmons, Alina Codita
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Aging Cell
instname
Aging Cell
Several studies support the relation between leptin and Alzheimer’s disease (AD). We show that leptin levels in CSF are unchanged as subjects progress to AD. However, in AD hippocampus, leptin signalling was decreased and leptin localization was sh
Autor:
Marián Castro, Felipe F. Casanueva, Maria Lodeiro, Rubén Nogueiras, Monica Bouzo-Lorenzo, Yolanda Pazos, Adrian J. Butcher, Jesus P. Camiña, Andrew B. Tobin, Icía Santo-Zas
Publikováno v:
Scientific Reports
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
The growth hormone secretagogue receptor, GHSR1a, mediates the biological activities of ghrelin, which includes the secretion of growth hormone, as well as the stimulation of appetite, food intake and maintenance of energy homeostasis. Mapping phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb2277957e5ff3a79429a453cec3e77
https://hdl.handle.net/10347/15909
https://hdl.handle.net/10347/15909
Autor:
Muhammad-Al-Mustafa Ismail, Cristina Parrado-Fernandez, Alina Codita, Paula Merino-Serrais, Silvia Maioli, Maria Lodeiro, Elena Puerta, Patricia Rodriguez-Rodriguez, Annica Rönnbäck, Angel Cedazo-Minguez, Francisco J. Gil-Bea
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 72(3)
Inflammation plays an important role in Alzheimer's disease (AD) and other neurodegenerative disorders. Although chronic inflammation in later stages of AD is well described, little is known about the inflammatory processes in preclinical or early st
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Increasing evidence suggest that Alzheimer's disease (AD) is a heterogeneous disorder that includes several subtypes with different etiology and progression. Cerebrospinal fluid (CSF) is being used to find new biomarkers reflecting the complexity of
Autor:
Carlos S. Mosteiro, Jesus P. Camiña, Felipe F. Casanueva, Yolanda Pazos, Uxía Gurriarán-Rodríguez, Xesús Casabiell, Monica Bouzo-Lorenzo, Maria Lodeiro, Icía Santos-Zas
Publikováno v:
The international journal of biochemistrycell biology. 45(7)
β-Arrestins were identified as scaffold-proteins that have the capacity to desensitize G protein-coupled receptors. However, it has been found that β-arrestins activate signaling pathways independent of G protein activation. The diversity of these
Autor:
Jesus P. Camiña, Daniel Beiroa, Rosalia Gallego, Rubén Nogueiras, Carlos S. Mosteiro, Felipe F. Casanueva, María Pardo, Yolanda Pazos, Begoña O. Alén, Marily Theodoropoulou, Maria Lodeiro
Publikováno v:
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Molecular Biology of the Cell
Servizo Galego de Saúde (SERGAS)
Molecular Biology of the Cell
The SHP-1 tyrosine phosphatase is a negative regulator of ghrelin activity, being a critical signaling component for proper regulation of Akt-dependent processes. Based on the SHP-1 expression pattern in white adipose tissue (WAT) and its regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572c949090edc0e153953e885beb4ddc
http://hdl.handle.net/20.500.11940/5551
http://hdl.handle.net/20.500.11940/5551