Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maria Liljevald"'
Autor:
Angela Woods, Jennet R. Williams, Phillip J. Muckett, Faith V. Mayer, Maria Liljevald, Mohammad Bohlooly-Y, David Carling
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3043-3051 (2017)
AMP-activated protein kinase (AMPK) plays a key role in integrating metabolic pathways in response to energy demand. We identified a mutation in the γ1 subunit (γ1D316A) that leads to activation of AMPK. We generated mice with this mutation to stud
Externí odkaz:
https://doaj.org/article/ef62f181128e4d0bbe4ebc25109d1987
Retinoid-related orphan receptor γ (RORγ) adult induced knockout mice develop lymphoblastic lymphoma
Autor:
Camilla Johansson, Magnus Söderberg, Jenny Börjesson, Jorrit J. Hornberg, Marie Ramnegård, Maria Rehnberg, Maria Liljevald, Donatella Luciani, Johan Jirholt, Ulf Andersson, Lena Brändén, David J. Keeling, Anna-Karin Sjögren, Xiufeng Xu, Nina Krutrök, Mikael Bjursell
Publikováno v:
Autoimmunity Reviews. 15:1062-1070
RORγ is a nuclear hormone receptor which controls polarization of naive CD4+ T-cells into proinflammatory Th17 cells. Pharmacological antagonism of RORγ has therapeutic potential for autoimmune diseases; however, this mechanism may potentially carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32327bd242dabcc76c9a6e58cd89b0d
https://doi.org/10.1016/j.autrev.2016.07.036
https://doi.org/10.1016/j.autrev.2016.07.036
Autor:
Tommy B. Andersson, Gabriella Brolén, Anna Jonebring, Johanna Sagemark, Xue-Qing Li, Björn Glinghammar, Anna-Karin Sjögren, Maria Liljevald, Ian A. Cotgreave
Publikováno v:
Archives of Toxicology. 88:1427-1437
Human-induced pluripotent stem cell-derived hepatocytes (hiPSC-Hep) hold great potential as an unlimited cell source for toxicity testing in drug discovery research. However, little is known about mechanisms of compound toxicity in hiPSC-Hep. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f6a8c3b512f0ec0f651af5b564afb4
https://doi.org/10.1007/s00204-014-1265-z
https://doi.org/10.1007/s00204-014-1265-z
Autor:
Angela, Woods, Jennet R, Williams, Phillip J, Muckett, Faith V, Mayer, Maria, Liljevald, Mohammad, Bohlooly-Y, David, Carling
Publikováno v:
Cell Reports
Summary AMP-activated protein kinase (AMPK) plays a key role in integrating metabolic pathways in response to energy demand. We identified a mutation in the γ1 subunit (γ1D316A) that leads to activation of AMPK. We generated mice with this mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49870e933714bb9d8edb49f9698f149a
https://pubmed.ncbi.nlm.nih.gov/28355557
https://pubmed.ncbi.nlm.nih.gov/28355557
Autor:
Björn Glinghammar, Maria Liljevald, Anna-Karin Sjögren, Tommy B. Andersson, Aklexander Kvist, Henrik Palmgren, Gabriella Brolén
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2049998b14a8bf0a3ab66696aaa84c
https://doi.org/10.1096/fasebj.29.1_supplement.779.3
https://doi.org/10.1096/fasebj.29.1_supplement.779.3
Removal of damaged proteins during ES cell fate specification requires the proteasome activator PA28
Autor:
Marija Cvijovic, Åsa Fredriksson, Thomas Nyström, Maria Liljevald, Karin Norrman, Henrik Semb, John Wiseman, Malin Hernebring
Publikováno v:
Scientific Reports
In embryonic stem cells, removal of oxidatively damaged proteins is triggered upon the first signs of cell fate specification but the underlying mechanism is not known. Here, we report that this phase of differentiation encompasses an unexpected indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e100e25569fb895f8b5dde6839d795
http://europepmc.org/articles/PMC3587881
http://europepmc.org/articles/PMC3587881