Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maria Leticia Castro"'
Publikováno v:
Antioxidants, Vol 6, Iss 3, p 58 (2017)
We have previously shown that exposure to high dose ascorbate causes double stranded breaks (DSBs) and a build-up in S-phase in glioblastoma (GBM) cell lines. Here we investigated whether or not this was due to genotoxic stress as well as metabolic s
Externí odkaz:
https://doaj.org/article/cd77ac50c4ff450eb74e589793c6caa7
Autor:
Maria Leticia Castro, Diane Fatkin, Anne Keogh, Christopher S. Hayward, Jonathan G. Seidman, Libin Wang, Robert M. Graham, Orit Wolstein, Milena B. Furtado, Natalie Cochrane, Nadia Rosenthal, Robyn Otway, Peter Riek, Christopher Semsarian, Robert G. Weintraub, Richard P. Harvey, Peter S. Macdonald, Mauro W. Costa, Molly Vale, Christine E. Seidman, Guanglan Guo, Thomas Yeoh, Michael P. Feneley
Publikováno v:
Circulation. Cardiovascular genetics. 6(3)
Background— The transcription factor NKX2-5 is crucial for heart development, and mutations in this gene have been implicated in diverse congenital heart diseases and conduction defects in mouse models and humans. Whether NKX2-5 mutations have a ro
Autor:
Monique Ohanian, Stefan A. Mann, Kathryn Stockhammer, Diane Fatkin, Angela Sheu, Poonam Zodgekar, Jamie I. Vandenberg, Guanglan Guo, Rajesh N. Subbiah, Maria Leticia Castro, Dennis L. Kuchar, Anu Aggarwal, David Playford, T. Thompson
Publikováno v:
Journal of the American College of Cardiology. 60(16)
Objectives Our aim was to characterize a variant in the SCN5A gene that encodes the alpha-subunit of the cardiac sodium channel, Nav1.5, which was identified in 1 large kindred with dilated cardiomyopathy (DCM) and multiple arrhythmias, including pre