Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Maria Laura Falchetti"'
Autor:
Alessia Formato, Maria Salbini, Elisa Orecchini, Manuela Pellegrini, Mariachiara Buccarelli, Lucia Ricci Vitiani, Stefano Giannetti, Roberto Pallini, Quintino Giorgio D'Alessandris, Liverana Lauretti, Maurizio Martini, Valentina De Falco, Andrea Levi, Maria Laura Falchetti, Maria Patrizia Mongiardi
Publikováno v:
Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)
ABSTRACT Objective Axitinib is a tyrosine kinase inhibitor characterized by a strong affinity for Vascular Endothelial Growth Factor Receptors (VEGFRs). It was approved in 2012 by Food and Drug Administration and European Medicines Agency as a second
Externí odkaz:
https://doaj.org/article/7cc7cde955aa431da8a4db85e35cb3d3
Autor:
Matilde Merolle, Maria Patrizia Mongiardi, Maurizia Piras, Andrea Levi, Maria Laura Falchetti
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1490 (2020)
Axitinib is an orally available inhibitor of tyrosine kinases, with high specificity for vascular endothelial growth factor receptors (VEGFRs) 1, 2, and 3. It is approved for the treatment of advanced renal cell carcinoma and is in phase II clinical
Externí odkaz:
https://doaj.org/article/c520addda32747d8960714bde8c023b8
Autor:
Augusto Pessina, Arianna Bonomi, Valentina Coccè, Gloria Invernici, Stefania Navone, Loredana Cavicchini, Francesca Sisto, Maura Ferrari, Lucia Viganò, Alberta Locatelli, Emilio Ciusani, Graziella Cappelletti, Daniele Cartelli, Caruso Arnaldo, Eugenio Parati, Giovanni Marfia, Roberto Pallini, Maria Laura Falchetti, Giulio Alessandri
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28321 (2011)
BACKGROUND: Mesenchymal stromal cells may represent an ideal candidate to deliver anti-cancer drugs. In a previous study, we demonstrated that exposure of mouse bone marrow derived stromal cells to Doxorubicin led them to acquire anti-proliferative p
Externí odkaz:
https://doaj.org/article/5174bc7913e64a4e9255d3c0c5b705be
Autor:
Quintino Giorgio D'Alessandris, Marco Battistelli, Giovanni Pennisi, Martina Offi, Maurizio Martini, Tonia Cenci, Maria Laura Falchetti, Liverana Lauretti, Alessandro Olivi, Roberto Pallini, Nicola Montano
Publikováno v:
Expert Reviews in Molecular Medicine. 25
Glioblastoma (GBM) is the most frequent adult malignant brain tumour and despite different therapeutic efforts, the median overall survival still ranges from 14 to 18 months. Thus, new therapeutic strategies are urgently needed. However, the identifi
Autor:
Simone Pacioni, Quintino Giorgio D’Alessandris, Stefano Giannetti, Giuseppe Maria Della Pepa, Martina Offi, Martina Giordano, Valerio Maria Caccavella, Maria Laura Falchetti, Liverana Lauretti, Roberto Pallini
Publikováno v:
Cancers; Volume 14; Issue 12; Pages: 2844
5-aminolevulinic acid (5-ALA)-induced PpIX fluorescence is used by neurosurgeons to identify the tumor cells of high-grade gliomas during operation. However, the issue of whether 5-ALA-induced PpIX fluorescence consistently stains all the tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3042ef9f4d4191cc0fac709826af9b5
https://hdl.handle.net/10807/219372
https://hdl.handle.net/10807/219372
Autor:
Maria Patrizia Mongiardi, Mariachiara Buccarelli, Alessia Formato, Elisa Orecchini, Maria Salbini, Valentina Ricci, Tiziana Orsini, Sabrina Putti, Silvia Chiesa, Lucia Ricci-Vitiani, Quintino Giorgio D’Alessandris, Roberto Pallini, Andrea Levi, Maria Laura Falchetti
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6193
Glioblastoma (GBM), the most malignant primary brain tumor in adults. Although not frequent, it has a relevant social impact because the peak incidence coincides with the age of professional maturity. A number of novel treatments have been proposed,
Autor:
Lucia Ricci-Vitiani, Simone Pacioni, Valentina Lulli, Liliana Morgante, Maurizio Martini, Mariachiara Buccarelli, Luigi Maria Larocca, Maria Laura Falchetti, Stefano Giannetti, Quintino Giorgio D'Alessandris, Louis Stancato, Eliza Vakana, Roberto Pallini
Publikováno v:
International journal of cancer (Online) (2019). doi:10.1002/ijc.31983
info:cnr-pdr/source/autori:Falchetti ML1, D'Alessandris QG2, Pacioni S2, Buccarelli M3, Morgante L4, Giannetti S4, Lulli V3, Martini M5, Larocca LM5, Vakana E6, Stancato L6, Ricci-Vitiani L3, Pallini R2./titolo:Glioblastoma endothelium drives bevacizumab-induced infiltrative growth via modulation of PLXDC1/doi:10.1002%2Fijc.31983/rivista:International journal of cancer (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
International Journal of Cancer
info:cnr-pdr/source/autori:Falchetti ML1, D'Alessandris QG2, Pacioni S2, Buccarelli M3, Morgante L4, Giannetti S4, Lulli V3, Martini M5, Larocca LM5, Vakana E6, Stancato L6, Ricci-Vitiani L3, Pallini R2./titolo:Glioblastoma endothelium drives bevacizumab-induced infiltrative growth via modulation of PLXDC1/doi:10.1002%2Fijc.31983/rivista:International journal of cancer (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
International Journal of Cancer
Bevacizumab, a VEGF‐targeting monoclonal antibody, may trigger an infiltrative growth pattern in glioblastoma. We investigated this pattern using both a human specimen and rat models. In the human specimen, a substantial fraction of infiltrating tu
Autor:
Vittorio Stumpo, Liverana Lauretti, Mariachiara Buccarelli, Lucia Ricci-Vitiani, Roberto Pallini, Maria Laura Falchetti, Maurizio Martini, Martina Giordano, Luigi Maria Larocca, Rina Di Bonaventura, Quintino Giorgio D'Alessandris, Stefano Giannetti, Simone Pacioni, Nicola Montano
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2021 (2021)
BioMed Research International, Vol 2021 (2021)
The cranial window (CW) technique provides a simple and low-cost method to assess tumor angiogenesis in the brain. The CW combined with histology using selective markers for tumor and endothelial cells can allow a sensitive monitoring of novel antian
Autor:
Matilde Merolle, Maria Patrizia Mongiardi, Maria Laura Falchetti, Andrea Levi, Valentina Fustaino
Publikováno v:
Aging Clinical and Experimental Research (Online) (2019). doi:10.1007/s40520-019-01390-5
info:cnr-pdr/source/autori:Maria Patrizia Mongiardi Matilde Merolle Valentina Fustaino Andrea Levi Maria Laura Falchetti/titolo:Gene expression profiling of hypoxic response in different models of senescent endothelial cells/doi:10.1007%2Fs40520-019-01390-5/rivista:Aging Clinical and Experimental Research (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Maria Patrizia Mongiardi Matilde Merolle Valentina Fustaino Andrea Levi Maria Laura Falchetti/titolo:Gene expression profiling of hypoxic response in different models of senescent endothelial cells/doi:10.1007%2Fs40520-019-01390-5/rivista:Aging Clinical and Experimental Research (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
Endothelial cells senescence is a physiological process affecting vascular integrity. It can contribute to heart and arterial stiffening and remodeling, impaired angiogenesis, defective vascular repair, and with an increasing prevalence of atheroscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3c9daba8a68a9b06414eb032546ed9
http://hdl.handle.net/11573/1643970
http://hdl.handle.net/11573/1643970
Autor:
Maria Laura Falchetti, Andrea Levi, Maria Patrizia Mongiardi, Roberto Pallini, Manuela Pellegrini
Publikováno v:
Cancers
Cancers, Vol 13, Iss 484, p 484 (2021)
Cancers, Vol 13, Iss 484, p 484 (2021)
Simple Summary Cellular senescence consists of a permanent block of cell proliferation in the presence of an active metabolism. It is a physiological process occurring when cells exhaust their proliferative potential, as signaled by critical telomere