Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maria L. Pedersen"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract P-glycoprotein (P-gp), a membrane transport protein overexpressed in certain drug-resistant cancer cells, has been the target of numerous drug discovery projects aimed at overcoming drug resistance in cancer. Most characterized P-gp inhibito
Externí odkaz:
https://doaj.org/article/df7f2460da3440b9b4ed8eb6b299d08f
Autor:
Irina E. Antonescu, Maria Karlgren, Maria L. Pedersen, Ivailo Simoff, Christel A. S. Bergström, Sibylle Neuhoff, Per Artursson, Bente Steffansen, Carsten Uhd Nielsen
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 390 (2020)
Acamprosate is an anionic drug substance widely used in treating symptoms of alcohol withdrawal. It was recently shown that oral acamprosate absorption is likely due to paracellular transport. In contrast, little is known about the eliminating mechan
Externí odkaz:
https://doaj.org/article/98594dfdbdd9410b820f985d165d6cfa
Autor:
Carsten Uhd Nielsen, Nanna Friberg Krog, Ilham Sjekirica, Sidsel Strandgaard Nielsen, Maria L. Pedersen
Publikováno v:
Pflugers Archiv : European journal of physiology. 474(12)
Solute carriers (SLC) are important membrane transport proteins in normal and pathophysiological cells. The aim was to identify amino acid SLC(s) responsible for uptake of sarcosine and glycine in prostate cancer cells and investigate the impact here
Autor:
Maria Hytti, Johanna Ruuth, Iiris Kanerva, Niina Bhattarai, Maria L. Pedersen, Carsten U. Nielsen, Anu Kauppinen
Publikováno v:
Molecular and cellular biochemistry.
During age-related macular degeneration (AMD), chronic inflammatory processes, possibly fueled by high glucose levels, cause a breakdown of the retinal pigment epithelium (RPE), leading to vision loss. Phloretin, a natural dihydroxychalcone found in