Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maria L. Lombardi"'
Autor:
Philipp Isermann, Diana E. Jaalouk, Jan Lammerding, Maria L. Lombardi, Monika Zwerger, Monika Mauermann, Harald Herrmann, George Dialynas, Lori L. Wallrath
Publikováno v:
Human Molecular Genetics. 22:2335-2349
Lamins are intermediate filament proteins that assemble into a meshwork underneath the inner nuclear membrane, the nuclear lamina. Mutations in the LMNA gene, encoding lamins A and C, cause a variety of diseases collectively called laminopathies. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2b4076df13b2fc54b2be94075eca7d
https://doi.org/10.1093/hmg/ddt079
https://doi.org/10.1093/hmg/ddt079
Autor:
Jan Lammerding, Catherine M. Shanahan, Brian Burke, Diana E. Jaalouk, Kyle J. Roux, Maria L. Lombardi
Publikováno v:
Journal of Biological Chemistry. 286:26743-26753
Maintaining physical connections between the nucleus and the cytoskeleton is important for many cellular processes that require coordinated movement and positioning of the nucleus. Nucleo-cytoskeletal coupling is also necessary to transmit extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4388fdde0da102b75103d4e5907276a
https://doi.org/10.1074/jbc.m111.233700
https://doi.org/10.1074/jbc.m111.233700
Publikováno v:
Journal of Cell Science. 120:1624-1634
Continuous cell movement requires the coordination of protrusive forces at the leading edge with contractile forces at the rear of the cell. Myosin II is required to generate the necessary contractile force to facilitate retraction; however, Dictyost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c054a70f1e1299b9e4433e6c0cd80ddb
https://doi.org/10.1242/jcs.002527
https://doi.org/10.1242/jcs.002527
Autor:
Jan Lammerding, Maria L. Lombardi
Providing a stable physical connection between the nucleus and the cytoskeleton is essential for a wide range of cellular functions and it could also participate in mechanosensing by transmitting intra- and extra-cellular mechanical stimuli via the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0beb3f02f315b9de5aadd0dc35d04d3
https://europepmc.org/articles/PMC4589539/
https://europepmc.org/articles/PMC4589539/
Publikováno v:
Scopus-Elsevier
In most eukaryotic cells, the nucleus is the largest organelle and is typically 2 to 10 times stiffer than the surrounding cytoskeleton; consequently, the physical properties of the nucleus contribute significantly to the overall biomechanical behavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebb008c7cacc76b957631d422666f7f
https://europepmc.org/articles/PMC3230193/
https://europepmc.org/articles/PMC3230193/
Autor:
J. Christopher Love, Rohit Karnik, Weian Zhao, Maria L. Lombardi, Weisuong Teo, Sebastian Schafer, Charles P. Lin, Alicia L. Carlson, Cheryl H. Cui, Jeffrey M. Karp, Rakesh K. Jain, Joseph A. Phillips, Yvonne J. Yamanaka, Suman Bose, Debanjan Sarkar, Jonghoon Choi, Ilia A. Droujinine, Jan Lammerding
Publikováno v:
PubMed Central
Author Manuscript 2012 August 1.
The ability to explore cell signalling and cell-to-cell communication is essential for understanding cell biology and developing effective therapeutics. However, it is not yet possible to monitor the interaction
The ability to explore cell signalling and cell-to-cell communication is essential for understanding cell biology and developing effective therapeutics. However, it is not yet possible to monitor the interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56f101171b5f6749efbefdcda008ac3
http://hdl.handle.net/1721.1/78868
http://hdl.handle.net/1721.1/78868
Autor:
Jan Lammerding, Maria L. Lombardi
In eukaryotic cells, the nucleus is the largest and most rigid organelle. Therefore, its physical properties contribute critically to the biomechanical behavior of cells, e.g., during amoeboid migration or perfusion through narrow capillaries. Furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfaae0cd0073712b0d0024c0e0318f4
https://doi.org/10.1016/s0091-679x(10)98006-0
https://doi.org/10.1016/s0091-679x(10)98006-0
Autor:
Francesca Romana Mauro, Ileana De Michele, Daniele Castiglia, Ester Simeone, Rosa Calemma, Caterina Ieranò, Stefania Scala, P. Giuliano, Corrado Caracò, Paolo A. Ascierto, Gerardo Botti, Monica Luongo, Maria Napolitano, R. A. Satriano, Renato Franco, Gianfranco Nicoletti, Giuseppe Castello, Alessandro Ottaiano, Maria L. Lombardi
Purpose: The chemokine receptor CXCR4 was identified as an independent predictor of poor prognosis in primary melanoma. The aim of the study was to investigate the role of CXCR4 in human melanoma metastases. Experimental Design: CXCR4 expression was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b709821cbcb18e36b59116087327568c
http://hdl.handle.net/11591/189235
http://hdl.handle.net/11591/189235
Autor:
Maria L. Lombardi
Publikováno v:
Biochemical Society Transactions; Dec2011, Vol. 39 Issue 6, p1729-1734, 6p