Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maria L. Ibba"'
Autor:
Maria L. Ibba, Giuseppe Ciccone, Deborah Rotoli, Gabriele Coppola, Alfonso Fiorelli, Silvia Catuogno, Carla L. Esposito
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 111-126 (2023)
The identification of new effective therapeutic options for non-small-cell lung cancer (NSCLC) represents a crucial challenge in oncology. Recent studies indicate that cancer-associated fibroblasts (CAFs) participate in tumor progression by establish
Externí odkaz:
https://doaj.org/article/355f7b2b64c748fa9e32d04320a16a88
Autor:
Carla L. Esposito, Ida Autiero, Annamaria Sandomenico, H. Li, Mahmoud A. Bassal, Maria L. Ibba, Dongfang Wang, Lucrezia Rinaldi, Simone Ummarino, Giulia Gaggi, Marta Borchiellini, Piotr Swiderski, Menotti Ruvo, Silvia Catuogno, Alexander K. Ebralidze, Marcin Kortylewski, Vittorio de Franciscis, Annalisa Di Ruscio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Here the authors generate an RNA-based platform to neutralize the major epigenetic player DNMT1. Using this targeted approach, aberrant DNA methylation in cancer can be corrected.
Externí odkaz:
https://doaj.org/article/1ac7b00822ad42efaffe5d498c64c726
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6075 (2020)
Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer worldwide, with the highest incidence in developed countries. NSCLC patients often face resistance to currently available therapies, accounting for frequent relapses and poor p
Externí odkaz:
https://doaj.org/article/6ecf5700b0df401788b81f9d5f279d41
Publikováno v:
Cancers, Vol 12, Iss 6, p 1365 (2020)
Tumor mass consists of a complex ensemble of malignant cancer cells and a wide variety of resident and infiltrating cells, secreted factors, and extracellular matrix proteins that are referred as tumor microenvironment (TME). Cancer associated fibrob
Externí odkaz:
https://doaj.org/article/75fbc9a0e9294730a420390131cc30e2
Publikováno v:
Advanced drug delivery reviews. 177
Messenger RNAs (mRNAs) present a great potential as therapeutics for the treatment and prevention of a wide range of human pathologies, allowing for protein replacement, vaccination, cancer immunotherapy, and genomic engineering. Despite advances in
Autor:
Carla L. Esposito, Ida Autiero, Annamaria Sandomenico, H. Li, Mahmoud A. Bassal, Maria L. Ibba, Dongfang Wang, Lucrezia Rinaldi, Simone Ummarino, Giulia Gaggi, Marta Borchiellini, Piotr Swiderski, Menotti Ruvo, Silvia Catuogno, Alexander K. Ebralidze, Marcin Kortylewski, Vittorio de Franciscis, Annalisa Di Ruscio
Publikováno v:
Nature communications. 14(1)
DNA methylation is a fundamental epigenetic modification regulating gene expression. Aberrant DNA methylation is the most common molecular lesion in cancer cells. However, medical intervention has been limited to the use of broadly acting, small mole
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6075, p 6075 (2020)
International Journal of Molecular Sciences
International journal of molecular sciences (Online) 21 (2020): 1–27. doi:10.3390/ijms21176075
info:cnr-pdr/source/autori:Rotoli D.; Santana-Viera L.; Ibba M.L.; Esposito C.L.; Catuogno S./titolo:Advances in oligonucleotide aptamers for NSCLC targeting/doi:10.3390%2Fijms21176075/rivista:International journal of molecular sciences (Online)/anno:2020/pagina_da:1/pagina_a:27/intervallo_pagine:1–27/volume:21
International Journal of Molecular Sciences
International journal of molecular sciences (Online) 21 (2020): 1–27. doi:10.3390/ijms21176075
info:cnr-pdr/source/autori:Rotoli D.; Santana-Viera L.; Ibba M.L.; Esposito C.L.; Catuogno S./titolo:Advances in oligonucleotide aptamers for NSCLC targeting/doi:10.3390%2Fijms21176075/rivista:International journal of molecular sciences (Online)/anno:2020/pagina_da:1/pagina_a:27/intervallo_pagine:1–27/volume:21
Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer worldwide, with the highest incidence in developed countries. NSCLC patients often face resistance to currently available therapies, accounting for frequent relapses and poor p
Autor:
Carla Lucia Esposito, Maria L Ibba, Silvia Nuzzo, Silvia Catuogno, Lucia Ricci-Vitiani, Gerolama Condorelli, Roberto Pallini, Vittorio de Franciscis
Publikováno v:
Cancers, Vol 12, Iss 1434, p 1434 (2020)
Cancers (Basel) 12 (2020). doi:10.3390/cancers12061434
info:cnr-pdr/source/autori:Esposito C.L.; Nuzzo S.; Ibba M.L.; Ricci-Vitiani L.; Pallini R.; Condorelli G.; Catuogno S.; de Franciscis V./titolo:Combined targeting of glioblastoma stem-like cells by neutralizing RNA-bio-drugs for STAT3/doi:10.3390%2Fcancers12061434/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Cancers
Volume 12
Issue 6
Cancers (Basel) 12 (2020). doi:10.3390/cancers12061434
info:cnr-pdr/source/autori:Esposito C.L.; Nuzzo S.; Ibba M.L.; Ricci-Vitiani L.; Pallini R.; Condorelli G.; Catuogno S.; de Franciscis V./titolo:Combined targeting of glioblastoma stem-like cells by neutralizing RNA-bio-drugs for STAT3/doi:10.3390%2Fcancers12061434/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Cancers
Volume 12
Issue 6
An important drawback in the management of glioblastoma (GBM) patients is the frequent relapse upon surgery and therapy. A likely explanation is that conventional therapies poorly affect a small population of stem-like cancer cells (glioblastoma stem
Publikováno v:
Cancers (Basel) 12 (2020). doi:10.3390/cancers12061365
info:cnr-pdr/source/autori:Santana-Viera L.; Ibba M.L.; Rotoli D.; Catuogno S.; Esposito C.L./titolo:Emerging therapeutic RNAs for the targeting of cancer associated fibroblasts/doi:10.3390%2Fcancers12061365/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Cancers, Vol 12, Iss 1365, p 1365 (2020)
Cancers
info:cnr-pdr/source/autori:Santana-Viera L.; Ibba M.L.; Rotoli D.; Catuogno S.; Esposito C.L./titolo:Emerging therapeutic RNAs for the targeting of cancer associated fibroblasts/doi:10.3390%2Fcancers12061365/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Cancers, Vol 12, Iss 1365, p 1365 (2020)
Cancers
Tumor mass consists of a complex ensemble of malignant cancer cells and a wide variety of resident and infiltrating cells, secreted factors, and extracellular matrix proteins that are referred as tumor microenvironment (TME). Cancer associated fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb4326b481d9fd317d1fed132a3ae77
http://www.scopus.com/inward/record.url?eid=2-s2.0-85085595811&partnerID=q2rCbXpz
http://www.scopus.com/inward/record.url?eid=2-s2.0-85085595811&partnerID=q2rCbXpz