Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Maria L. Freilino"'
Autor:
Malabika Sen, Netanya I. Pollock, John Black, Kara A. DeGrave, Sarah Wheeler, Maria L. Freilino, Sonali Joyce, Vivian W.Y. Lui, Yan Zeng, Simion I. Chiosea, Jennifer R. Grandis
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 3, Pp 256-264 (2015)
Aberrant activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) 3 has been implicated in cell proliferation and survival of many cancers including head and neck squamous cell carcinoma (HNSCC). AZD1480, an orally
Externí odkaz:
https://doaj.org/article/43e98c263c804a90b459b9325da12bcb
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 2.2MB, Modified STAT3 decoys demonstrate enhanced resistance to thermal denaturation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f5870414757b94ce3c02ac424e1aa7
https://doi.org/10.1158/2159-8290.22528743.v1
https://doi.org/10.1158/2159-8290.22528743.v1
Autor:
Jennifer R. Grandis, Ching-Shih Chen, Andre Cassell, Anirban Sahu, Sufi M. Thomas, Malabika Sen, Sonali C. Joyce, Maria L. Freilino, Neil E. Bhola
PDF file, 39KB, IC50 values for AR-12 in HNC and 1 normal cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f83de065f499583bc6c346148bbdba
https://doi.org/10.1158/1535-7163.22497915.v1
https://doi.org/10.1158/1535-7163.22497915.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 1.2MB, Modified STAT3 decoys bind to pSTAT3 protein with similar affinity as the parental STAT3 decoy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30539ef8faef811ec7986b2385e8d410
https://doi.org/10.1158/2159-8290.22528740.v1
https://doi.org/10.1158/2159-8290.22528740.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 107K, Systemic delivery of cyclic STAT3 decoy does not affect total or pSTAT3 expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2098d043169646d758cfedaf2f14b31a
https://doi.org/10.1158/2159-8290.22528731
https://doi.org/10.1158/2159-8290.22528731
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 2.5MB, The chemistry used to generate the modified decoys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65178b04076c5c2db95c2225b4ffcfd2
https://doi.org/10.1158/2159-8290.22528746.v1
https://doi.org/10.1158/2159-8290.22528746.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 70K, Lack of anti-tumor effects of systemically administered parental STAT3 decoy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e9b9985992180cd4f087112f286b66
https://doi.org/10.1158/2159-8290.22528749.v1
https://doi.org/10.1158/2159-8290.22528749.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 2MB, Modified STAT3 decoys abrogate STAT3 target gene expression in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bbd05e6d8072276dd17a459c3c4745
https://doi.org/10.1158/2159-8290.22528737
https://doi.org/10.1158/2159-8290.22528737
Autor:
Jennifer R. Grandis, Ching-Shih Chen, Andre Cassell, Anirban Sahu, Sufi M. Thomas, Malabika Sen, Sonali C. Joyce, Maria L. Freilino, Neil E. Bhola
PDF file, 106KB, AR-12 decreases cyclin D1 expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db766a48ab4c94f78a012bbda8044e4
https://doi.org/10.1158/1535-7163.22497930.v1
https://doi.org/10.1158/1535-7163.22497930.v1
Autor:
Jennifer R. Grandis, Daniel E. Johnson, Kusum Pandit, Naftali Kaminski, Xiaomin Chen, William E. Gooding, Raja R. Seethala, Simion Chiosea, Lin Wang, Pui-Kai Li, Jonathan P. Etter, Srinivas Rapireddy, Danith Ly, Changyou Li, Haibin Shi, Maria L. Freilino, Sonali Joyce, Nivedita Sahu, Jessica Lee, Umamaheswar Duvvuri, Jonas T. Johnson, Robert L. Ferris, Joanne I. Yeh, Seungwon Kim, Sufi M. Thomas, Malabika Sen
PDF file - 165K, EC50 values of STAT3 decoy in cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f54801fbcf326d28c1e2e05e484c5d
https://doi.org/10.1158/2159-8290.22528722.v1
https://doi.org/10.1158/2159-8290.22528722.v1