Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Maria Kouyoumdjian"'
Autor:
Pedro L. R. Guedes, Carolina P. F. Carvalho, Adriana A. F. Carbonel, Manuel J. Simões, Marcelo Y. Icimoto, Jair A. K. Aguiar, Maria Kouyoumdjian, Marcos L. Gazarini, Marcia R. Nagaoka
Publikováno v:
Molecules, Vol 27, Iss 3, p 654 (2022)
During liver fibrogenesis, there is an imbalance between regeneration and wound healing. The current treatment is the withdrawal of the causing agent; thus, investigation of new and effective treatments is important. Studies have highlighted the acti
Externí odkaz:
https://doaj.org/article/5b277a8e6ddf4bf2ba64dda4068eb24a
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 81, Iss 3, Pp 431-442 (2009)
Portal hypertension is the most common complication of chronic liver diseases, such as cirrhosis. The increased intrahepatic vascular resistance seen in hepatic disease is due to changes in cellular architecture and active contraction of stellate cel
Externí odkaz:
https://doaj.org/article/d595d7965b6e4569a742c6b10c2e8308
Autor:
Maria Kouyoumdjian
Publikováno v:
Brazilian Journal of Medical and Biological Research
It has been previously demonstrated that the hemodynamic effect induced by angiotensin II (AII) in the liver was completely abolished by losartan while glucose release was partially affected by losartan. Angiotensin II type 1 (AT1) and adrenergic (
Autor:
Thelma A. Pertinhez, Michael Blaber, Maria Kouyoumdjian, Thierry Moreau, Diego M. Assis, Robson A.S. Santos, Maria A. Juliano, Thaysa Paschoalin, Francis Gauthier, Luiz Juliano, João B. Calixto
Publikováno v:
Biochemical Pharmacology. 97:203-214
Phosphorylated kininogen and some of its fragments containing serine phosphorylated bradykinin ([pS(6)]-Bk) were identified in human serum and plasma by a phosphoproteomic approach. We report the kininogenase ability of human tissue and plasma kallik
Autor:
Maria Kouyoumdjian, Sheila Siqueira Andrade, Priscila Totarelli Monteforte, Misako U. Sampaio, Antonio Miranda, Guiomar Silva Lopes, Soraya S. Smaili, Maria Luiza Vilela Oliva
Publikováno v:
bchm. 393:943-957
BbKI is a kallikrein inhibitor with a reactive site sequence similar to that of kinins, the vasoactive peptides inserted in kininogen moieties. This structural similarity probably contributes to the strong interaction with plasma kallikrein, the enzy
Autor:
Maria Kouyoumdjian, Durval Rosa Borges, Giuseppe D'Ippolito, Danilo Moulin Sales, David Carlos Shigueoka, Luciane Kopke-Aguiar, Paulo Eugênio Brant
Publikováno v:
Acta Tropica. 108:218-221
We previously reported that in anicteric patients with the isolated form of schistosomiasis (without comorbidities) an ursodeoxycholic acid-sensitive increase in serum gamma-glutamyltransferase activity (GT) occurs. We now describe the presence of ch
Autor:
Marcia R. Nagaoka, Felipe Oliveira Teixeira, Leda Teixeira Carvalho, Durval Rosa Borges, Maria Kouyoumdjian, Écio Alves Nascimento
Publikováno v:
Journal of Gastroenterology and Hepatology. 22:1543-1548
Background and Aim: Angiotensin I (AI) and angiotensin II (AII) induce a portal hypertensive response (PHR) and the liver is able to convert AI into AII to trough the action of the angiotensin-converting enzyme (ACE). Our purpose was to characterize
Publikováno v:
Peptides. 26:1301-1307
The purpose of this brief review is to describe some characteristics of the kallikrein–kinin system (KKS) in the liver. The liver synthesizes kininogens and prekallikrein and the synthesis of both proteins is increased in rats during the acute phas
Autor:
Luciana Gioli-Pereira, Leda Teixeira Carvalho, Edson Lucas dos Santos, Durval Rosa Borges, João Bosco Pesquero, Maria Kouyoumdjian, Écio Alves Nascimento
Publikováno v:
Peptides. 26:315-322
To ascertain the mechanism of interaction between angiotensins (AI and AII) and the liver, an angiotensin-converting enzyme inhibitor (captopril) and a receptor antagonist (losartan) were used. Monovascular or bivascular liver perfusion was used to a
Autor:
Marcelo Y. Icimoto, Maria Kouyoumdjian, Marcia R. Nagaoka, Marcos L. Gazarini, Jair A.K. Aguiar, Pedro Luiz Rodrigues Guedes
Publikováno v:
Journal of Hepatology. 66:S389