Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maria Konstantoulaki"'
Autor:
Tiffany Sharma, Arun Roy, Maria Konstantoulaki, Asrar B. Malik, Nebojsa Nick Knezevic, Dolly Mehta, Barbara Timblin
Publikováno v:
Molecular and Cellular Biology. 27:6323-6333
We identified the GDI-1-regulated mechanism of RhoA activation from the Rho-GDI-1 complex and its role in mediating increased endothelial permeability. Thrombin stimulation failed to induce RhoA activation and actin stress fiber formation in human pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ade804a2d63b4b45a72ecbd884756c
https://doi.org/10.1128/mcb.00523-07
https://doi.org/10.1128/mcb.00523-07
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 285:L434-L442
The adherens junction is a multiprotein complex consisting of the transmembrane vascular endothelial cadherin (VEC) and cytoplasmic catenins (p120, β-catenin, plakoglobin, α-catenin) responsible for the maintenance of endothelial barrier function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0465d3532f5c868ef845d770102bc1e9
https://doi.org/10.1152/ajplung.00075.2003
https://doi.org/10.1152/ajplung.00075.2003
The Role of Focal Adhesion Kinase in Sphingosine‐1‐Phosphate Induced Endothelial Barrier Enhancement
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb94188a5fd947a131f9f69272345dea
https://doi.org/10.1096/fasebj.22.1_supplement.1178.1
https://doi.org/10.1096/fasebj.22.1_supplement.1178.1
Autor:
Maria Konstantoulaki, Larry R. Brown, Claire M. Mulvey, Richard Sainsbury, Jasminka Godovac-Zimmermann
Publikováno v:
Expert review of proteomics. 4(2)
Proteomics has lacked adequate methods for handling the complexity (hundreds of thousands of different proteins) and range of protein concentrations (or =10(6)) of eukaryotic proteomes. New multiphoton-detection methods for ultrasensitive detection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2aca902721c4a981f6f14b17cc74e6
https://pubmed.ncbi.nlm.nih.gov/17425453
https://pubmed.ncbi.nlm.nih.gov/17425453
Publikováno v:
The Journal of biological chemistry. 280(17)
Sphingosine 1-phosphate (S1P) ligation of endothelial differentiation gene-1 receptor coupled to the heterotrimeric G protein, Gi, promotes endothelial barrier strengthening via Rac-dependent assembly of adherens junctions (AJs). However, the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2455ca321496448b3da4c9572484803
https://pubmed.ncbi.nlm.nih.gov/15728185
https://pubmed.ncbi.nlm.nih.gov/15728185
Publikováno v:
Circulation research. 94(2)
The mechanisms involved in the restoration of endothelial cell junctions subsequent to barrier disruption remain unclear. It is known that formation of adherens junctions (AJs) affects cytoskeletal actin arrangement and that Rho GTPases regulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74fec740140c0507a458a34a0ac9752
https://pubmed.ncbi.nlm.nih.gov/14656933
https://pubmed.ncbi.nlm.nih.gov/14656933
VE-cadherin-induced Cdc42 signaling regulates formation of membrane protrusions in endothelial cells
The cytoplasmic domain of cadherins and the associated catenins link the cytoskeleton with signal transduction pathways. To study the signaling function of non-junctional VE-cadherin, which can form during the loss VE-cadherin homotypic adhesion, wil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869b814c7723dbc556d99063610f2707
http://olympias.lib.uoi.gr/jspui/handle/123456789/18177
http://olympias.lib.uoi.gr/jspui/handle/123456789/18177
