Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Maria Kolak"'
Autor:
Jan Liska, Per Tornvall, Staffan Bjessmo, Maria Kolak, Per Eriksson, Martin Halle, Mattias Ekström, Rachel M. Fisher
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 299:E234-E240
Adipose tissue (AT) is a store of energy but also an endocrine organ with the capacity to produce and release proinflammatory mediators into the circulation. The mechanism that may trigger human AT inflammation on a cellular level still remains large
Autor:
Rachel M. Fisher, Ursula Turpeinen, Anders Hamsten, Anja Cornér, Maria Kolak, Janne Makkonen, Hannele Yki-Järvinen, Jukka Westerbacka
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 294:E841-E845
CCL2 (MCP-1, monocyte chemoattractant protein 1) and CCL3 (MIP-1alpha, macrophage inflammatory protein 1alpha) are required for macrophage infiltration in adipose tissue. Insulin increases CCL2 expression in adipose tissue and in serum more in insuli
Autor:
Robert Bergholm, Maria Kolak, Vidya Velagapudi, Janne Makkonen, Rachel M. Fisher, Hannele Yki-Järvinen, Dick Wågsäter, Aila Rissanen, Monica Lindell, Per Eriksson, Laxman Yetukuri, Anders Hamsten, Jukka Westerbacka, Anna-Maija Häkkinen, Matej Orešič
Publikováno v:
Kolak, M, Westerbacka, J, Velagapudi, V, Wågsäter, D, Yetukuri, L, Makkonen, J, Rissanen, A, Häkkinen, A-M, Lindell, M, Bergholm, R, Hamsten, A, Eriksson, P, Fisher, R M, Orešič, M & Yki-Järvinen, H 2007, ' Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity ', Diabetes, vol. 56, no. 8, pp. 1960-1968 . https://doi.org/10.2337/db07-0111
OBJECTIVE— We sought to determine whether adipose tissue is inflamed in individuals with increased liver fat (LFAT) independently of obesity. RESEARCH DESIGN AND METHODS— A total of 20 nondiabetic, healthy, obese women were divided into normal an
Autor:
Rachel M. Fisher, Maria Kolak, Jussi Sutinen, Jukka Westerbacka, Hannele Yki-Järvinen, A. Cornér, Janne Makkonen, Anders Hamsten
Publikováno v:
International Journal of Obesity. 31:1617-1625
To determine whether increased expression of macrophage markers and of inflammatory markers in subcutaneous adipose tissue is associated with liver fat in human obesity. We also determined whether expression of TNF (gene encoding TNF-alpha), HSD11B1
Autor:
Katja Kannisto, Maria Kolak, Anders Hamsten, A. Cornér, Tuulikki Nyman, Janne Makkonen, Rachel M. Fisher, E Korsheninnikova, Hannele Yki-Järvinen, Jukka Westerbacka
Publikováno v:
Diabetologia. 49:132-140
We determined the response of selected genes to in vivo insulin in adipose tissue in 21 non-diabetic women.The women were divided into insulin-sensitive and -resistant groups based on their median whole-body insulin sensitivity (8.7+/-0.4 vs 4.2+/-0.
Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue
Autor:
Scott A. Summers, Matej Orešič, Anders Franco-Cereceda, Maria Kolak, Joanna Gertow, Rachel M. Fisher, Per-Olof Eriksson, Jan Liska, Hannele Yki-Järvinen, Jukka Westerbacka
Publikováno v:
Kolak, M, Gertow, J, Westerbacka, J, Summers, S A, Liska, J, Franco-Cereceda, A, Orešič, M, Yki-Järvinen, H, Eriksson, P & Fisher, R M 2012, ' Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue ', Lipids in Health and Disease, vol. 11, 115 . https://doi.org/10.1186/1476-511X-11-115
Lipids in Health and Disease, Vol 11, Iss 1, p 115 (2012)
Lipids in Health and Disease
Lipids in Health and Disease, Vol 11, Iss 1, p 115 (2012)
Lipids in Health and Disease
Background Inflammation and increased ceramide concentrations characterise adipose tissue of obese women with high liver fat content compared to equally obese women with normal liver fat content. The present study characterises enzymes involved in ce
Autor:
Tuula Kiviluoto, Petri Auvinen, Maria Kolak, Perttu Arkkila, Jukka Westerbacka, Hannele Yki-Järvinen, Rachel M. Fisher, Oscar Puig, Saara Laitinen, Dario Greco, Anna Kotronen, Anders Hamsten
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 294(5)
Despite the high prevalence of nonalcoholic fatty liver disease (NAFLD), little is known of its pathogenesis based on study of human liver samples. By the use of Affymetrix GeneChips (17,601 genes), we investigated gene expression in the human liver
Autor:
Madeleine Linestrand, Per Sjögren, Anna-Lena Undén, Ulf de Faire, Justo Sierra-Johnson, Maria Kolak, Magdalena Rosell, Mai-Lis Hellénius, Rachel M. Fisher
Publikováno v:
Obesity (Silver Spring, Md.). 16(6)
Background: Skipping meals is a common practice in our current society; however, it is not clear whether eating meals regularly is associated with the metabolic syndrome. Objective: Our aim was to assess the association of eating meals regularly with
Autor:
Maria Kolak, Anders Hamsten, Katja Kannisto, Rachel M. Fisher, Hannele Yki-Järvinen, Mirja Tiikkainen, Per Eriksson
Publikováno v:
The Journal of clinical endocrinology and metabolism. 92(2)
The aim of this study was to compare effects of therapeutic doses of rosiglitazone and metformin on expression of 50 genes in human adipose tissue in vivo.Twenty patients with diet-treated type 2 diabetes (13 women, seven men) were randomized to rece
Autor:
Mai-Lis Hellénius, Lena Kallings, Kerstin Brismar, Rachel M. Fisher, Ulf de Faire, Per Sjögren, Tommy Cederholm, Mats Halldin, Justo Sierra-Johnson, Maria Kolak
Publikováno v:
Lipids in Health and Disease
Lipids in Health and Disease, Vol 11, Iss 1, p 80 (2012)
Lipids in Health and Disease, Vol 11, Iss 1, p 80 (2012)
Background A sedentary lifestyle predisposes to cardiometabolic diseases. Lifestyle changes such as increased physical activity improve a range of cardiometabolic risk factors. The objective of this study was to examine whether functional changes in