Výsledky vyhledávání - "Maria K. Traver"

Akademický článek

Signaling through polymerization and degradation: Analysis and simulations of T cell activation mediated by Bcl10.

Autor: Leonard Campanello, Maria K Traver, Hari Shroff, Brian C Schaefer, Wolfgang Losert

Publikováno v: PLoS Computational Biology, Vol 17, Iss 5, p e1007986 (2021)

The adaptive immune system serves as a potent and highly specific defense mechanism against pathogen infection. One component of this system, the effector T cell, facilitates pathogen clearance upon detection of specific antigens by the T cell recept

Externí odkaz: https://doaj.org/article/410e6f8f72684783986f3c0b857dcfc2

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T Cell Receptor Activation of NF-κB in Effector T Cells: Visualizing Signaling Events Within and Beyond the Cytoplasmic Domain of the Immunological Synapse

Autor: Maria K, Traver, Suman, Paul, Brian C, Schaefer

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1584

The T cell receptor (TCR) to NF-κB signaling pathway plays a critical role in regulation of proliferation and effector T cell differentiation and function. In naïve T cells, data suggest that most or all key cytoplasmic NF-κB signaling occurs in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c00353e494954fe0d97fd587e648828
https://pubmed.ncbi.nlm.nih.gov/28255699

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A transient Malt1 aggresome sustains T cell receptor signaling to NF-κB

Autor: Maria K. Traver, Leonard Campanello, Celeste Huaman, Suman Paul, Hari Shroff, Wolfgang Losert, Brian C. Schaefer

Publikováno v: The Journal of Immunology. 200:112.2-112.2

The T cell receptor (TCR) to NF-κB signaling pathway is crucial for T cell activation and differentiation. Upon engagement of the TCR with cognate antigen, a series of events leads to the formation of the Carma1-Bcl10-Malt1 (CBM) complex, increasing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12b1e71bc6b5d8d6e7510681d2bbf914
https://doi.org/10.4049/jimmunol.200.supp.112.2

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Coalescence of Nanoscale Cytoplasmic Signalosomes Contributes to T Cell Receptor Signaling to NF-κB

Autor: Maria K Traver, Leonard Campanello, Suman Paul, Hari Shroff, Wolfgang Losert, Brian C Schaefer

Publikováno v: The Journal of Immunology. 198:52.13-52.13

T cell receptor (TCR) activation of the transcription factor NF-κB is a crucial determinant of effector T lymphocyte function. The complex regulatory network surrounding this pathway remains poorly understood, particularly at time periods further re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6718f593528354147110700e0e1d771
https://doi.org/10.4049/jimmunol.198.supp.52.13

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